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Marija Kundakovic: Epigenetics, Brain Sex Differences, Environmental Factors, and Mental Health 

BRAIN PONDERINGS podcast with Mark Mattson
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The brains of males and females are different and it is important to understand how these differences give rise to different behavioral traits of men an women. These sex differences arise during brain development, manifest throughout life and are controlled in part by estrogen and testosterone. The brains of females and males, and their differential vulnerability to mental and other neurological disorders may be influenced by prenatal and early life environmental factors including stress or exposure to pollutants such as ‘forever chemicals’. Professor Mariha Kundakovic at Fordham University is making major contributions to understanding brain sex differences and particularly the roles of ‘epigenetic’ molecular and structural modifications to the genome. Here she talks about her research and its implications for the causes of and treatments for anxiety disorders and depression.
LINKS:
Review article: epigenetic mechanisms and sex differences in the brain and behavior:
www.ncbi.nlm.nih.gov/pmc/arti...
Review on influence of hormones on the brain during the estrous cycle:
www.ncbi.nlm.nih.gov/pmc/arti...
Sex hormones and risk for anxiety disorders and depression:
www.ncbi.nlm.nih.gov/pmc/arti...

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28 фев 2024

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Комментарии : 2   
@eugeniebreida1583
@eugeniebreida1583 3 месяца назад
So glad to hear from Marija . . .thank you Mark!
@eugeniebreida1583
@eugeniebreida1583 3 месяца назад
Hello you two. My Mother, maternal Grandmother AND myself had our final periods at 41, 39, and 40 respectively. Not sure about GM, but Mother and I had Zero post-menopausal symptoms. Personally I had extreme dark moods one+ days before period, and terrible night-sweats, etc., in perimenopause. And Lots of insomnia since undergrad years, through today (age 65 yrs). THANK YOU to Marija for inspiring even this sharing of mine, of female aspects of brain/body health.
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