New Trends in Therapy for Androgenic Alopecia Part 2 

It's good to note that the emerging therapy on balding is definitely taking a new dimension on targeting the specific culprit creating baldness. 👍

🎯 Key Takeaways for quick navigation: 02:29 👤 Androgen receptor binding preference leads to hair loss. 04:23 🛠️ Specific anti-androgen blockers are researched to target DHT receptors. 05:16 💼 Class coderone (breezula) is being explored for androgenetic alopecia. 07:19 🎯 Targeted therapy with blockers and stimulation offers potent approach. 08:43 🧪 Treatment customization and patient compliance are crucial for success. Made with HARPA AI

Please, please, please, talk more about mesotherapy. I think my doctor here in South America has never done a treatment based only in the use of mesotherapy, without any oral alpha reductase blocker. She said I will be doing mesotherapy each six months, but you guys said 2 months and maybe it is because two months is the ideal frame when mesotherapy is the only technique being used as a treatment. Please, talk about this. I may suggest my doctor that I will be doing it each two months. She will agree.

Tell us more on peptides, please. ❤ your videos are realistically educational

Please can you do a review on Nanoxidil, has it any improvement over the regular monoxidal. Thanks, this is the best channel for her loss I have came across, keep up the good work 🙂.

Hi doctors, thank you for all the valuable information. I have a question: In regards to Finasteride frequency: in your previous video you said taking Finasteride daily "makes no sense" due to its long half-life. But you also say that when customizing the dosage "you may need to be more aggressive in the therapy." My question is: do you ever come across a patient that actually requires 1mg Finasteride/day, or 7mg a week? What is an example of "being aggressive with therapy" when it comes to Finasteride?

Blocking Androgen receptor cause feminisation for men but it s benefic for Woman So could we use it to irradicate Androgen Alopecia for Women ??!!!

Great videos, thank you for posting. What are your thoughts on CosmeRNA?

whats the name of this new product, which you cant use now. what is about prylumimaid?

great content, will you be covering scube 3 in any follow up videos?

Hi Dr, I’ve been following you lately about this interesting topic. I totally now understand the difference between hair loss and shedding. However, I just wonder is there a thing called seasonal shedding, For example end of summer and fall? I know this is not Telogen effluvium, and could only relates to season or perhaps the hair enters the Telogen cycle in this specific time of the year. I would love if you can shed more lights on that topic. Thank you.

Thanks for these great videos Just one recommendation, the writing on the whiteboard is too small.

Hello. I enjoy your videos which are very informative. In addition to peptides, please can you also do a video on Polynucleotide hair treatments.

Dear, after a hair transplant, when can you start using hair fibers again? And when can you start microneedling again? Thanks in advance!

Hey guys, what are your thoughts on DS Laboratories? In particular their shampoo and conditioner and the topicals like Spectral DNC-N and Spectral F-7?

Please do an episode on oral minoxidil and its dose for male and female patients

What happened to your partnership with the UK company?

Could addition of DMSO help with topical delivery?thank you for your informative videos. Love the channel!

Great video. What do you think of“laser” or light stimulation for the scalp? I assume its just another stimulation technique but does it work?

can you guys make a video on people wanting to go on finasteride as a preventative measure (pre-hairloss) and whether its effectiveness will diminish in the long term meaning that if you go on it too early that you will have unnecessary diminishing results?

Do we know if statins, such as atorvastatin can reduce the effectiveness of finasteride?

Breezula, pyralutamide and gt20029 are super likely to get the fda approval. Breezula is starting phase 3 in the us, pyralutimide is starting phase 3 in the us and China, and gt20029 is currently in phase 2

Any thoughts on SCUBE3 and Osteopontin signaling growth factors?

I had a hair transplant back in 2005. The procedure went well and the hair growth wss good. After about 5 years i noticed dry skin with a group of hairs clumped together.. it wss very odd. I didnt lose much but it definitely affected thd density. I dont know if that' was my native hair or yhe transplanted hair. I really have never recieved any explanation for this.. I started on oral finistride in 2018 and used it until 2023 and noticed ths hair thicknesses inproved and less shedding. I stopped oral finistride and started topical minoxidil and finistride. Its been about 5 months but i havent seen the sams results as oral finistride and I'm not sure i will. Any thoughts on why the dry skin and hair fall after the hair transplants?? I still have maintained much of my hair but the density is poor.

Can you touch on hair fibers. Are they safe? Do they potentially exacerbate hair loss? Thank you!

Is there anything that can regrow hair....in the front area....The hairline. Also....for those hairs that have stopped growing...Is there anything that can restart them growing.. Finasteride has stopped all falling hair..but...I'm concerned about the other two issues.. Now, I have seen videos in which they claim...Minoxidil did nothing for them.. at all. If you will, give me an answer here...or do a video on it.. Thanks!

What do you think about topical spirolactone? I have seen people crush the pills and mix them with minoxidil. Spirolactone is supposed to be an androgen blocker

Please write the name of the hairloss androgen-receptor-specific drug under development. It was not clear from the discussion. I was aware that DHT is more selective for hairloss than T, but I wasn't aware that there are DHTs that are more selective for hairloss than other DHTs. Is that the point?

Guys, I have 6 bottles of Minoxidil on my table and too scared to use it. I have heard that once you start Minoxidil your hair can become dependent on it to such an extent that once or if you stop taking minoxidil you will be MORE bald than you were to begin with. In other words, that prexisting hairs that werent yet balding at onset of Minoxidil treatment, will be pushed into otherwise avoidable (when paired with other treatments) balding stages once you stop taking Minoxidil. Can you confirm or adress this topic?

Hello, doc do you know if i can mix my ru58841 with trichosol as a vechile with also dutasteride in it? Thank you

Hi bit of a random q. Do corticosteroids increase hair loss. Specifically salbutamol for asthma? Just wondering if this will affect dht levels and the ability of finasteride to do it's job? There doesn't seem to be a lot of information about this tbh

I use a microdose of finasteride due to side effects and use RU

Would the anti-androgen receptor stuff cause regrowth or would it just limit future losses?

I have a question, I use minoxidil 2% once a night and for the last 19 days and it makes me really lightheaded the night of and following day (but my shedding has slowed down already) could I still get some benefits if I used it every other day? to help remove the light headedness? I know the half life is 23 hours, so could every other day still bring benefits and be better than not using it at all?

What about for women

Good

Would u recommend alopecia or oral minoxidil?????

Thats why Dutasteride is mote powerful than finasteride. Also Dutasteride doesnt cause severe sides effects like finasteride. Dutasteride has been also shown to reduce scarring of hairfollicles and scalp which is very interesting

Please talk about SAW PALMETTO!

Put chapters into your vids, a lot of the video is good old info most of the community knows already.

Is 0.25mg 7am morning and 7pm evening better than 0.5mg evening for fin?

Hi, is it safe to take both oral finasteride and oral minoxidil?

Is Dr Knudsen still using minoxidil? His senescent alopecia seems to have progressed a lot recently.

Sounds like a win for SARMS hahah.

scube3

You lost me at transgender, cisgender...

unsubscribed at "cisgender"

You lost me at “cis gender” 👋

You lost all credibility after you said cisgender. 🥴🤦🏻

Personally I cannot stand Knudsen.