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Parkinson's Disease High Dose Thiamine (B1) Therapy: An overview 

Sergio Pièche
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This 16-minute Presentation gives an overview on High Dose Thiamine (B1) therapy in Parkinson's Disease and explains why this therapy holds a high potential as an intervention to modify the course of Parkinson’s Disease. It goes through Dr Costantini’s research work, ending with the plan to confirm his preliminary findings through a Randomized, Double-Blind, Placebo Control Trial (RCT). Donations to support the study can be made through GoFundMe at www.gofundme.c... . Disclaimer - This presentation is provided for information and education purposes only. You should consult your physician for advice on treatment, including supplements. Supplements may interact with other supplements, medicines and other health conditions, so check with your doctor first. The findings presented are only preliminary findings and need still to be confirmed. Any actions taken based on what is provided and mentioned in this Presentation is your sole responsibility. I disclaim any liability, loss or risk, personal or otherwise, including death, that is incurred as a consequence, directly or indirectly, from the use, misuse and application of any suggestions or information contained in the Presentation.

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20 авг 2024

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Комментарии : 50   
@lolafalana2021
@lolafalana2021 8 месяцев назад
I started taking B1 for three weeks now, 500mg in the morning and 500 at noon. My tremor is nearly gone, my nightmares stopped, I also take fish oil and turmeric, thank you for this video
@B1Therapy
@B1Therapy 8 месяцев назад
Good to hear that.
@rkymtngal
@rkymtngal Месяц назад
how are you doing now, I see it has been 6 months, newly diagnosed here
@lazoolazoo3771
@lazoolazoo3771 Год назад
I have been taking 400 mg of TTFD, 600 mg of Benfotiamine and 600 mg of HCL religiously daily for three months now and I have noticed zero improvement in my shaking hands, slouching posture, slow movement or immense fatigue. I am bummed out about this, but I am not giving up. Going to continue. Fingers are crossed.
@alexisdaniel3313
@alexisdaniel3313 Год назад
TTFD and Benfotiamine are liposolubles as for Vitamin A and D3 well known as having toxicity at high doses! I wonder whether you had paradoxical reaction with such amount? I tried 50mg daily allithiamine and noticed less fatigue the first week . Then it started to deteriorate and improved by reducing every two days! Please note that i noticed it works only with supplements of Mg, B6, and B12. No tremors reduction after two months.
@B1Therapy
@B1Therapy Год назад
Have you tried to follow the B1 therapy protocol? It is well described in Daphne's Bryan book on Parkinson's and the B1 therapy. It is also described in our website b1parkinsons.org with background scientific evidence on each component
@alexisdaniel3313
@alexisdaniel3313 Год назад
@@B1Therapy not yet. Thank you for challenging me. I’ll buy the book.
@monik8868
@monik8868 11 месяцев назад
Constantini used only water soluble B1, 2 x 1000 mg / day in oral use ('Benfotiamine' is fat soluble, and that is for treating periferral neuropathy. 'TTFD' is a very high concentrated type of B1, be careful with that dose. Constantini did not used any of them, only the normal thiamine B1)
@user-nd6so7yg2y
@user-nd6so7yg2y 11 месяцев назад
Go to research and studies on " SULFORAPHANE " with Parkinsons damged mitrocondrial. "It is restoring my gut in 4 weeks from 50 years of IBS and constupation. It comes from Kale powder , broccoli heads raw and spiach powder amazon. Stay at 64 mgs a day or less. STUDY : pubmed.ncbi.nlm.nih.gov/33207780/
@genarodiaz699
@genarodiaz699 Год назад
Thanks a lot. The Dr. Constantini will never be forgotten; i am sure that the doctor's work will have the worldwide recognition it deserves.
@B1Therapy
@B1Therapy Год назад
Thanks for your comment, Genaro. We hope that it wll possible to conduct a large trial in the future, to confirm his findings. This is also what he was hoping for. Meanwhile, this is to let you know that we launched our b1parkinsons.org website on B1 therapy just last night.
@marilemos6810
@marilemos6810 10 месяцев назад
Although many allopathic doctors say that PD has no cure, functional doctors give hope to people suffering from this neurodegenerative disease, they say that every disease can be cured because our magical body is made to heal and repair any disease.
@ionationat3570
@ionationat3570 3 месяца назад
best, thank you.
@B1Therapy
@B1Therapy Месяц назад
Welcome!
@alexisdaniel3313
@alexisdaniel3313 Год назад
PLEASE NOTE THAT THE MEGADOSE OF THIAMINE HCL APPEARS AS A SUCCESS BUT THERE IS NOT A SINGLE VIDEO OF A PERSON HAVING OBTAINED RESULTS BY INCREASING THE CONCENTRATION OF TTFD, BENFOTHIAMINE, AND OTHER THIAMINE TYPES THAN THE WATER SOLUBLE THIAMINE HCL!
@B1Therapy
@B1Therapy Год назад
TTFD, Benfotiamine and other forms of thiamine have not yet been studied in Parkinson's disease. There is very little experience in their use in Parkinson's to share until now. They have been used extensively in thiamine deficiency.
@gltam1057
@gltam1057 10 месяцев назад
Is there any chance that b1 could help with the Parkinson related disease called Dystonia ?? Thank you. 🙏
@lolafalana2021
@lolafalana2021 8 месяцев назад
I started vitamin b1 500mg twice a day after two weeks it made a drastic difference in my arm tremor, for example taking it from a 10 to a 1, I also take fish oil which fixed my memory issues, now I remember very clearly where I put my keys, the reason why I walked in a room and small details of my day, melatonin for sleeping and it made my nightmares almost disappear, had to become a vegan and workout every day, I don't wish this on anyone and will not feel sorry for myself, I will fight this and so far I have not noticed progression. So far I'm able to keep my job and perform well without attracting attention to myself.
@zonderbaar
@zonderbaar Год назад
Grazie per il tuo lavoro !
@B1Therapy
@B1Therapy 11 месяцев назад
Un po' in ritardo... ma grazie a te!
@gabyfridman7475
@gabyfridman7475 Год назад
Thank you !!!
@B1Therapy
@B1Therapy Год назад
Welcome!
@juliajimenez7157
@juliajimenez7157 Месяц назад
Dr. Buenos días. Yo soy paciente con Parkinson diagnosticado hace 19 meses actualmente manejada con levodopa carvidopa. E inicie terapia con tiamina 100 mg a la semana llevo 5 dosis se esta vitamina. Si Usted permite podría ser parte de su estudio. Soy colombiana y americana y resido en los dos países temporalmente. Fui enfermera profesional ya no ejerzo. Tengo 69 años. Agradezco su atención y me interesa mucho su investigación gracias
@B1Therapy
@B1Therapy Месяц назад
We are looking for funds for the study. Meanwhile, if you wish, you may join the Facebook group on Parkinson's b1 therapy (with Daphne Bryan as the administrator) , which counts over 11,000 people and which provides support and guidance on b1 therapy to persons with Parkinson’s. facebook.com/groups/parkinsonsb1therapy
@lorisullivan6231
@lorisullivan6231 6 месяцев назад
What is the status off double blind study? IMO and others in medical field..open studies w no control are pretty worthlessness and impossible to read without considerable of placebo effect
@B1Therapy
@B1Therapy 6 месяцев назад
Still lobbying to find donors willing to support an RCT on b1 in Parkinson's. About the placebo effect, you may wish to read our website section on it at b1parkinsons.org/evidence (6th item of the 7-item list.
@humerafazal7693
@humerafazal7693 10 месяцев назад
How can get vitamin B1 treatment
@endthe.1percent
@endthe.1percent 8 месяцев назад
On own if doctor doesn’t help. Amazon
@lolafalana2021
@lolafalana2021 8 месяцев назад
I started 500mg of vitamin b1 twice a day and my tremor went from a 10 to a one, huge difference but it tookabout two weeks, I also take fish oil which fixed my memory issues and melatonin to sleep which drastically reduced the nightmares
@B1Therapy
@B1Therapy 8 месяцев назад
For more information on thiamine in Parkinson's you may join facebook.com/groups/parkinsonsb1therapy
@salvoscuba
@salvoscuba Год назад
Grazie
@B1Therapy
@B1Therapy 11 месяцев назад
Grazie a te!
@RafaelMelatonina
@RafaelMelatonina 7 месяцев назад
Can I use Thiamine instead of Benfotiamine?
@B1Therapy
@B1Therapy 7 месяцев назад
No clinical trial on the use of benfotiamine in Parkinson's has been conducted to date, although it is a legitimate candidate, as ut has shown in pre-clinical studies to have antioxidant and anti-inflammatory effects and reduce microglia activation. The B1 protocol currently refers to b1 ( thiamine HCL).
@wendywood2215
@wendywood2215 Год назад
'PromoSM' ☹️
@tantk6187
@tantk6187 Год назад
Losing not loosing
@user-fh7lo6si8f
@user-fh7lo6si8f Год назад
“Types of Parkinson’s Symptoms Symptoms of Parkinson’s vary by the type of parkinsonism and between individuals. An individual with Parkinson’s will not necessarily experience all or even most symptoms. Parkinson’s is a progressive disease, which means that symptoms worsen gradually over time, new symptoms appear, and disability accumulates. Motor Symptoms Everyone with Parkinson’s experiences symptoms related to movement, known as motor symptoms. In early stages of Parkinson’s, motor symptoms are typically unilateral - limited to one side of the body. Motor symptoms are the hallmarks of parkinsonism, and the condition cannot be diagnosed without them. The most common motor symptoms of Parkinson’s include: Bradykinesia (Slowed movement) Tremor Rigidity Loss of balance Other motor symptoms of parkinsonism include: Stooped posture Shuffling gait Dystonia (repetitive twisting, swaying, or head-bobbing motions) Painful muscle contractions Muscle jerks or twitches Freezing episodes Mask-like facial expression Decreased blinking Softer, slurred, or mumbled speech Speaking in a monotone voice Drooling Dysphagia (difficulty swallowing) Micrographia (small handwriting) Slowed or abnormal eye movements Eyelid spasms Difficulty opening the eyes Nonmotor Symptoms Many people with Parkinson’s experience other types of symptoms in addition to motor symptoms. Cognitive Symptoms According to studies, about 40 percent of those with Parkinson’s eventually experience cognitive difficulties. Cognitive changes, often referred to collectively as “cog fog” or “brain fog,” can include problems with memory, attention, processing information, finding the right words, slurred speech, learning and remembering new things, organization, and getting lost in familiar places. Psychotic Symptoms Between 20 percent and 40 percent of people who take medications for parkinsonism experience a loss of connection with reality known as psychosis. Psychosis can either be caused directly by the disease or as a side effect of treatment. Psychotic symptoms can include: Visual hallucinations Delusions Paranoia Irrational fears Flashbacks Nightmares Sensory Symptoms Decreased sense of smell is very common and often among the earliest symptoms of Parkinson’s. Approximately 96 percent of people newly diagnosed with Parkinson’s show a loss of sense of smell. Some people with Parkinson’s experience vision changes, including blurred vision, double vision, loss of sensitivity in the perception of color and contrast, and visual hallucinations. The sense of taste may also be affected by parkinsonism. Mood and Personality Changes Parkinson’s and medications for the condition often cause changes in mood and can affect personality traits. Psychological symptoms of Parkinson’s can include: Depression Anxiety Anger Irritability Jealousy Increased or decreased interest in sex Impulsiveness Compulsive behavior Other Symptoms Fatigue is common in Parkinson’s. Fatigue may not be caused directly by Parkinson’s, but stem from other symptoms, including motor difficulties, sleep problems, and depression, or be among the side effects of medication for parkinsonism. Problems with sleep are widespread in people with Parkinson’s. Sleep disturbances are the most common sleep symptom, but insomnia, restless legs syndrome, nightmares, and difficulty turning over in bed are also experienced. Orthostatic hypotension is the scientific term for feeling dizzy when you stand up. It is a common symptom of Parkinson’s - experienced by 20 to 30 percent of those with the condition - and can lead to faints and dangerous falls. Orthostatic hypotension is a result of low blood pressure either due to nerves damaged by the disease or as a side effect of Parkinson’s medication. Orthostatic hypotension usually happens within three minutes of standing. This symptom is more likely the older you get and the longer you have Parkinson’s. Gastrointestinal (GI) symptoms, especially constipation, are among the most common Parkinson’s symptoms. Bladder dysfunction is common in Parkinson’s. As many as 50 percent of those with advanced Parkinson’s report overactive bladder. Pain in Parkinson’s disease comes in many varieties. Although Parkinson’s is not widely considered a painful disease, it can cause muscle pain from cramps and repetitive movements, neuropathy (nerve pain, or pins-and-needles numbness sensation), shooting pain such as sciatica, or a sharp, burning pain. Pain usually occurs on the side of the body most affected by Parkinson’s symptoms. It is common for people with Parkinson’s to experience sexual dysfunction. Parkinson’s causes lowered libido and difficulty orgasming in both sexes. Motor symptoms can also make physical aspects of sex problematic. In men, Parkinson’s leads to erectile dysfunction and ejaculation problems. In women, decreased arousal, vaginal dryness, and pain with intercourse occur. In about 1 percent of people with Parkinson’s, medications cause hypersexuality - compulsive sexual behavior. People with Parkinson’s are four times more likely to develop melanoma, a dangerous type of skin cancer. Those who have had melanoma are four times more likely to develop Parkinson’s.” Hi! I'm new to this group. I recently joined because I am the administrator of an international Parkinson’s support group. We have 8,700 members, no subscription fee, no sales. In Facebook click on the title of the group and a series of comments and information links appear. Facebook: Parkinson’s thiamine hcl
@jamesquick403
@jamesquick403 Год назад
😅😅
@jamesquick403
@jamesquick403 Год назад
9999
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