James Ironside is Professor of Clinical Neuropathology at the University of Edinburgh and Director of the MRC Network of UK Brain Banks. Recorded on 4 November 2010 at the Anatomy Lecture Theatre.
Really detailed and well-explained! I'm doing an APA styled college-level research paper about the evolution of prions for my 10th-grade class. Needless to say, your lecture will be cited in-text repeatedly throughout my paper. Thank you for the presentation, Mr. Ironside!
The Spanish and British smuggled sheep called Merinos which were renowned for their glossy wool and bred them with British sheep to increase the amount of meat on them which inadvertently spread Scrapie.
"Creutzfeld-Jakob" disease and "Gerstmann-Straussler-Scheinker" disease ... okay, that is really not easy for an non-native German speaker. It´s even a tongue-breaker to us.
What are the chances of a new wave/breakout of vCJD in the future? Incubation time in some kuru cases are crazy long, arent they? The Last kuru victim died in 2005 (or 2009 some say) and they say that they stopped eating human meat in the early 1960s. So this would be a time gap of 40+ years.
So you are telling me you can't detect this in people other than a brain biopsy?!? that is shocking we need to improve this! What's to say we don't all have some level of prions in the brain? What are some ways the immune system can fight them?
The thing is nothing can get rid of them, nothing we know today can actually get rid of these disease prions and they are almost undetectable untill the very last years of sufferers life
I’m a regular blood donor but I wouldn’t take blood from someone else unless it’s life or death. This is why I refused blood transfusion when I was anaemic. They wanted to give me a bag of blood after giving birth, but I opted out, my levels weren’t so bad as to it being emergency and I opted out.
Is it possible that perhaps chaperones are somehow involved in both, prion diseases as well as others such as Alzheimer's, seeing as both involve misfolded proteins?