I really enjoy the stories when you start talking about just the chemical makeup and breaking down the different ways to create chemical makeups I don't really follow that well as I'm not too big into chemistry. But when you tell one of your stories involving chemistry I absolutely love it. I wish I understood more about chemistry so I can enjoy the other videos more as well. But in any case I just want to thank you for your hard work and time spent making these videos, I really enjoy them!
Dave thank you! Really interesting, and timely since I’ve been watching the series about opioid addiction “Crime of the Century” the facts surrounding that are terrifying.
I have autism/Asperger's. this topic is one of my special interests along with the German corporate mergers that occured within the same industry. I really appreciate you for creating this content! I subscribed upon seeing the title and look forward to watching more.
Well my father writes the scripts for this series, and someone else does the animation, so if you call that a collaboration then yes that will continue.
What an incredible adventure you are taking us through, Professor Dave! It really is amazing how many advancements in science and mathematics happened entirely by accident. I guess it really does go to show that "The harder you practice, the luckier you become."
I don’t know if the original mauvine was actually light resistant but unfortunately most synthetic dies aren’t. They discolor with light, purple red and yellow tones in particular. As an artist working in oil and acrylic I learned that the hard way. Hell, had the same problem even with house paint. Fascinating video. 👍
Hoffman may have been wrong, because he was working with incorrect theoretical tools, but he still stepped forward, attempting to produce new results, RECORDING those results and adding to knowledge in this way.
Hey professor Dave I'm a regular visitor to your content. I think it's good stuff. At any rate I was watching a video by the state of Washington on a one pot synthesis and I was wondering if you were the chemist ?
I contracted herpes' I was told there is no Herpes cure except treatment to control it. I totally lost hope. All I could think was losing my life because it was so embarrassing to have this virus, few weeks ago I read about a possible natural cure which was guaranteed. And I ordered the treatment after some weeks I got 100% cure. Now I'm so excited to share this testimony thanks Dr okougbo Email:dr.okougboherbalhome@gmail.com.
Extraction of quinine from Cinchona bark was always my planned hobby project, not for its pharmaceutical properties, but for its intense blue fluorescence.
This is Great! I enjoyed every bit of it. Your presentation style is awesome. Was looking for a perfect introduction to Pharmacology. Please where are the remaining videos.. not produced yet?
Cool.. quinine is amazing but artemisin helped us overhand of this disease.. thus..malaria is still like a big bleeding, infectious(🙄) sore in our world. I hope We can use all our knowledge We HAD to take in the pandemic story too.. Then We start talking. This is in ALL ways so interesting and opens up so much.. 😐.. Thank You for another one incredible and well done vid in all of its aspects, Prof. Dave.. 👋🏼😌🇸🇪
I contracted herpes' I was told there is no Herpes cure except treatment to control it. I totally lost hope. All I could think was losing my life because it was so embarrassing to have this virus, few weeks ago I read about a possible natural cure which was guaranteed. And I ordered the treatment after some weeks I got 100% cure. Now I'm so excited to share this testimony thanks Dr okougbo Email:dr.okougboherbalhome@gmail.com.
No books, mostly specialized literature. Many chemistry and pharmacy journals publish historical accounts, which are always good sources of well-researched information.
Ehh almost all tonic water nowadays has basically zero quinine. Few years ago searched for a one that had decent levels. I love straight tonic water. It's like bitter Sprite
My only complaint is the picture you chose for 1850 was WAY off. Like... nearly 75 years off minimum. Wigs like that stopped being fashionable by the 1790s
I'm not sure if this type of soda is worldwide available. Here in the Netherlands it is. Quinine is added to Bitter Lemon to give it it's bitter taste.
@@eugeniebreida1583 This is the origin of the classic 'Gin & Tonic' cocktail. The sweet gin was added to cover the bitter taste of quinine in the tonic water.
@@sjholmesbrown Thank you for the correction, g&t's are obviously infinitely superior to vodka tonics. I'd forgotten, as ethanol is no longer on my 'list', age has a way of defeating alcohol metabolism for some of us, sadly. And now I see that your lesson alerts me that gin was added to get medicinal quinine down, for the soldiers?? And similar? Interesting back history.
Ah, not to be offensive , but there is a book , dated about 1965 written by Norman Taylor I think entitled " plant drugs that changed the world,"" and this book gives a very important different history of " Chinchona Bark ", Most notably the only high quinine yielding chinchona trees found after many years searching was the " Markham Trees" grown by the Dutch, With someone named " ledger" involved, resultd in trees producing bark containing at least 20 % quinine content, and higher., All other Cinchona trees produced bark contained 1 to 3% quinine content at best . The Dutch Quinine Monopoly was dominant worldwide and strategically critical for all nations especially during ww11. Please find and read that book, it gives a very exact history not found anywhere else, and it should be noted malaria has 3 types of the disease, which results in multi millions of deaths worldwide, yearly,.. even to current days.. Malaria is still a tremendous killer, with no end in sight............ Joseph Henry , Boise Idaho.
Mauve rhymes with drove or trove. So mauveine is just mauve with long "een" sound after it. Mauveine. Much the way quinine sounds, with the "een" as a suffix.
@@cambridgemart2075 My pleasure. I don't think they use "mauve" in the states. They just use "purple" for all those colours. And even if they did Webster & his "simplified English for semi literate cow pokes" would've... Oooh, difficult! "Move" is already a word. Well, that explains it's exclusion from his dictionary & thus it's disappearance from American English! I wonder if that's the case?
@@eugeniebreida1583 Oh! Thank you. I was obviously wrong. Thank you for putting me straight. I discovered that "Mauve" comes from the French word for "Mallow". A wild flower here with purple petals. And the "ine" just means that the substance is a basic alkaloid So Mauveine is "the basic alkaloid that dyes things the same colour as the petals of the plant Malva sylvestris or Mallow". Words fascinate me! :o)
@@Aengus42 I love words as well, though as an architect I tend to wander more around my pencil's end in the act of sketching. However, being a gardener, I'm with you on the mallows, and can attest to missing the very popular 'barnaby'?? Malta sylvestris, which graced a couple outer corners of my former urban 'farmhouse'. SO beautiful. I loved the soft light pink petals which were so profuse and yet delicate, like large snowy butterflies lighting upon the vertical stems. Maybe you can find the real name 'barnaby' is your first clue! : ) And thankfully I can say with confidence the petals' color is so comfortably distant from 'mauve' that the thought of 'it' would never enter my head! ; )
The standard American pronunciation of quinine is kwī-nīn, with the long I sound. Professor Dave is using the British pronunciation. Not wrong, but different from what I ever heard (and I heard a lot about malaria, since my father had contracted it on Guadalcanal).
True, but I have never heard the statement that the British pronunciation is "not wrong" vs. the American one. It is usually the other way around. Most people acknowledge that, in the English language, the English pronunciation is the standard one, but the American one can also be...acceptable.😊
@@ProfessorDaveExplains Me neither...and I would add it’s hard to find fault in your excellent research, and even better presentation. A Class, this one!