The Golden Era of Pharmaceutical Research 

Its really great to not have to deal with all those old diseases. Sometimes old people will be like "I remember being in bed for 3 weeks from djhdkc disease". And its some disease that makes your skin fall off and bones bend sideways!

Love this type of content thanks professor dave

What a wonderful video. All to often all I ever see on social media is anti-pharma rhetoric so this is a breath of fresh air. Some truly outstanding work, conducting by giants in their fields.

I love your content, im using it for improving my general knowledge aswell as improving my English skills (im German). I can usually keep up but sometimes I have to rewind and listen to some parts again ^^

Thanks so much, I am very happy to see more of this series!

Love this new series! Nice one Dave!

It would be awesome to learn about the differences in protein and steroid hormones. Maybe even more broad, like comparing lipid chemistry, protein chemistry, and sugars?

Love the vids bro. Keep them going.

Your videos are always so interesting.

A very happy teachers day to you professor!

Excellent, Marvelous. ..I m an Ortho, still longed for this for long time....Thanks A Million Ton Dear

Can't wait for the next installment!!

Nicely done 👍🏻✅

The playlist is very good and fantastic I am a pharmacist and i want more details about the history of drug can you give me accurate resources for that ??

Would be interested in hearing your take on Astral Projection, from the cia, the monroe institute, ancient religions from Egypt to India. Also a prominent idea amongst mesoamerican tribes. Do you think 1. People made up stories passed down over time, 2. Certain breathing exercises and sounds can trigger a local psychedelic level experience(my belief), 3. Some stuff about frequencies, earth magnetic resonance, or some other shit they say to justify an subjective brain experience into being real.

I dunno. I'm not like that the golden age is in black and white. What does that imply about today?

Typical Italian-style pasta: Let’s start with the basics. First, make the sauce: Pour a little olive oil over a finely chopped onion in a pan. Fry the onion until it’s golden and then add chopped tomatoes (about 800 grams) and salt. Simmer the sauce for 10 minutes. Now, for the pasta: Boil a large pot of salted water, and add the pasta (preferably, in order to follow Italian tradition, spaghetti). Remember: the pasta should be added only when the water is already boiling. Doing the opposite is a very common mistake. Stir it to keep the noodles from sticking. Taste the pasta to gauge its readiness (see below for more on how to make sure your pasta is al dente), and drain it when it’s done. Add the sauce and mix. Garnish with a sprinkling of Parmesan cheese or Grana Padano.

great video

Crazy how I literally had a random desire to search "history of drugs" and got your videos. I caught up with the whole series before this one and I'm stoked to see its an ongoing thing. 😁 I hope you get into some non-medicinal drug history such as ayahuasca, mushrooms, marijuana, the dea, timothy Leary, and modern designer drugs

Super cool

Don you need to see this, it's an epic series 🎉

Keep educating the masses. May Minerva be always with you.

what do you think of radio therapy

This is the best playlist ive listened to every video at least four times now so good especially for a long car ride

Hey Dave

This was amazing. Could you do one on the history of insulin? Why is it so expensive?

My dad worked in R&D for human and animal pharmaceuticals all my life until he retired a few years ago. He has friends from his time at Pfizer that worked on their Covid vaccine.

❤

On the issue of psychiatric Pharma, you need to look into the work of Robert Whitaker, who wrote Anatomy of an Epidemic. While they can help some, their side effects can be extreme and dangerous, and are largely ignored by psychiatry. There is also the antidepressant merry-go-round that keeps patients on these often-marginally-useful medications for years, switching from one to another when the first proves to be ineffective. The drug companies laugh all the way to the bank.

slay

Thank you chemistry Jesus

Wish we could get back to making medicines for the betterment of humanity instead of shareholder profits

Isn't the body wonderfully complex? Just my undergrad a+p, histology, biochem classes amazed me. NSAIDS have saved the day so many times! Can we get a "future of pharmaceuticals" video. The VA is already actively seeking volunteers so they can eventually use a test to see how an individual will respond to certain drugs and my dr. Tells me they may be able to customize your drugs through a computer program...? Sounds out there!

Ahhh time for some science jesus

The era of low hanging fruit for pharma. Before evergreening, publication bias, and inventing diagnoses.

Hope you have a nice day. We've summarized the main points discussed for convenience, but encourage watching the full video to get maximal value from the creator's knowledge. Click the link in my profile if you need summaries. Here is a summary of the key points from the transcript: 0:00 - Introduction. The post-WWII period was one of rebuilding and investment, which benefited the pharmaceutical industry. Leadership in the field shifted to the US. 0:30 - Discovery of cortisone as a treatment for rheumatoid arthritis by Philip Hench, Edward Kendall and Tadeusz Reichstein. Led to the 1950 Nobel Prize. Opened up steroid research and chemistry. 1:15 - Synthesis and production of cortisone by Merck chemists was an immense challenge. This effort established Merck as a top pharma lab. 2:00 - Discovery of NSAIDs like ibuprofen as simpler anti-inflammatory alternatives to steroids. 3:15 - Breakthrough in treating psychotic disorders with chlorpromazine, the first phenothiazine antipsychotic. Marked the beginning of more effective psychiatric treatments. 4:45 - Pioneering antimetabolite research by George Hitchings and Gertrude Elion at Burroughs Wellcome. Led to 6-mercaptopurine for leukemia treatment. 6:30 - The 1950s saw many important new drug discoveries, chemical and biological breakthroughs, and progress in previously untreatable diseases. 7:30 - The 1950s also marked the beginning of "lifestyle drug" research. Overall, the transcript covers key medical innovations in the pharmaceutical industry in the 1950s, including cortisone, NSAIDs, antipsychotics and antimetabolites. It highlights the rebuilding post-WWII and the rising leadership of the US pharma sector.

2nd defeat in 26 years. Your script is incorrect.

Dave, you preach that the earth is flat but you have to realize that most of the water is uncarbonated, making the earth pretty flat

video is too long for me, please make a short out of it.