Taurine: The Nutrient of Youth [Science Explained] 

3 Things: 1. On a quick search (I haven’t looked into this deeply), taurine seems to reduce or attenuate increases in cholesterol lipoproteins according to a meta-analysis (DOI: 10.1016/j.ejphar.2020.173533). So, as I suspected, it isn’t much of a worry (I’ll need to confirm this) - yet the association with increased blood levels is still a mystery - why do you think it might be the case? Let’s take some guesses! 2. And, apparently I see 'orange' as 'red', yet I'm not color blind.. 3. @6:43 - that should read 'SASP', not 'SAPS'.

I worked in health care for 33 years. The first 13 of those years was in a seniors' nursing home. I have seen residents who lived to be well into their 90's but were wheelchair bound since they were 70. Longevity IS NOT the preferred outcome (unless you are scared to die I suppose), but rather quality of life. Living to be 85 years old while still being active, independent, mobile, mostly free of pain and living and loving those you care about is the goal. When I look at these sorts of studies, I am interested in longevity potential but I key in on those aspects that imply a better quality of life, i.e. hirer bone density from Taurine supplementation.

Highlights 💡 Taurine supplementation increased lifespan by 10-12% in mice. 💡 Taurine supplementation reduced body fat, improved muscle strength, and blood sugar levels. 💡 Taurine showed potential in reducing senescent cells and increasing stem cells. 💡 The study suggests that taurine can be beneficial later in life, even if not taken in the earliest stages. 💡 While there are some potential negatives associated with taurine, further research is needed to fully understand its effects in humans.

Maybe our lives won’t be extended to a significant degree but taurine may help improve quality of life in our later years.

Very informative video. I am a 64 year old male. I started taking a Taurine 500mg supplement about 3 months ago. I have been getting better sleep. I have also noticed more energy. My sleep is more restful and deep. My energy has slightly increased. I plan to continue to take Taurine.

Taurine caused my dogs cataract to go away. It came back years later but Taurine again helped. My kitty was literally dying of heart disease. L Taurine brought him back and he lived quite some time after that.

well done. years ago, i found a book where a woman claimed to cure her asthma using vits a(retinol), c and e. it worked for me too. then it stopped working. but i noticed it worked after i'd eaten a tin of smoked oysters. i worked out it was the high level of taurine in oysters that was what enabled my body to make use of oil-based vitamins like retinol and vit e through the production of gall. i hope this information helps.

I’ve read it helps with tinnitus. A lot of people would love to hear you address that.

Since I feel having being called out I want to clarify some things: 1) the fact that I use your videos for taking naps doesn't mean I don't follow them, when I wake up I usually start again to the last thing I remember 2) it means you have a nice calming voice 3) I also use Andrew hubermann's videos for the same purpose because he has a warm calming voice.

Based on the content of the video, here's a summary of the key points discussed regarding the study on taurine and its potential effects on lifespan, health span, stem cells, and cellular senescence: 1. **Lifespan and Taurine Levels:** - The study measured taurine levels in blood across different biological systems, including mice, monkeys, and humans. - In humans, taurine levels decrease with age, with a significant reduction by age 50. - Mice were fed either a taurine-supplemented or non-supplemented diet. Those supplemented with taurine had a 10-12% longer lifespan compared to the non-supplemented group. - Notably, taurine supplementation began in middle age for the mice, suggesting its benefits can still be realized later in life. 2. **Metrics of Health Span:** - Taurine supplementation led to reduced body fat, improved muscle strength, and better blood sugar levels. - Bone health was positively impacted, with increased bone volume and improved bone strength observed in taurine-supplemented groups. 3. **Stem Cells and Cellular Senescence:** - Stem cells are crucial for healing and defense against pathogens, while senescent cells can negatively affect surrounding cells. - Taurine supplementation was associated with reduced cellular senescence markers in various tissues. - An experiment involving gene analysis suggested a potential increase in mitotically active stem cells due to taurine supplementation. 4. **Correlations and Interpretation:** - The study had animal models (mice) as well as data from monkeys and humans. - Positive correlations were found between taurine levels and various health markers, including reduced inflammation and obesity. - There were also negative correlations, such as dyslipidemia and elevated liver enzyme levels, that were not extensively discussed in the video. - The presenter emphasized the need to consider both positive and negative correlations and to avoid oversimplifying the results. 5. **Application and Implications:** - The presenter was cautious about the interpretation and emphasized the potential but speculative nature of the findings. - While taurine might not extend human lifespan by 12%, it could still have significant effects on overall health. - Taurine supplementation later in life could be impactful, potentially compensating for earlier lifestyle habits. - The presenter suggested watching their detailed study analysis for more comprehensive information on the findings.

I'm 44 years old, and I take taurine every day. I've been working in shifts for 18 years. Taurine is a salvation for my sleep, and as I train every day, strength and cardio it helps a lot to endure shifts, sleeping during the day and daily physical exercise.

I'm practically a 5 year old when it comes to these topics so I appreciate being taught this way! Thank you

One of the biggest problems with mouse studies, apart from the obviously massive gap in genetic makeup, is that their standard laboratory diet is extremely poor and unnatural. They are fed primarily corn and soy, both usually GMO. So basically any change in diet, or supplementation, may show an improvement where a more natural baseline diet would not. We just don’t know. That’s also how fad diets get started in human populations: the standard American diet is so poor in nutrients and rich in pollutants that almost any change will yield improvements.

Been taking it for 2 weeks and 3 days and on the 4th day I finally can feel the difference and I love it and feel great!

I love that our generation is pretty much the test subjects for thousands of supplements

I am 69 yoa. I had been taking 1grm/day taurine for 5 years. The new study on taurine up to 6 grms/day is game changing for me. So, I have several decades more extension in my healthy lifespan.

Why didn't you mention the red spot on kidney disease? Is elevated taurine linked to increased kidney disease? If so, that's important.

Thank you for being truthful and nuanced while still keeping it fun, I wish we had more content creator like you, cheers

I like this guy he is well presented and offers up the study rather then just take my word for as most do.

I'm nearing 70. As diabetic from the past (eight years on insulin after a heart attack), fasting one day a week (for 36-40 hours) led to improvement in A1C. Having been encouraged by this, I went aggressively for HFLC diet and overnight fasting (found out I 'm good at it!) with 7,000 steps everyday (sometimes within the house because of inclement weather) for over 7 months. However, I noticed I wasn't producing enough energy to go up a hill and my LdL and total cholesterol had gone up (and LdL above the range for the first time). The triglycerides remained below 80. A1C was 5.4. I had lost over 35 pounds and reached a BMI of 19.5 which worried my doctor. So I went for a week-long program (over the net) run by a famous doctor (doing research first using Atkins then Keto for over 25 years) but they were unable or unwilling to talk about how to address "low power". The course was mainly for people who had high BMI. I then went for an exercise bike after getting fooled by studies on "Italian alpine cyclists". Now after another 15 months, this June (2023), after 22 months being out of any medication for diabetes but still with "low power", I found you. You made me realize the folly of many things including "insulin resistance" for those who have no weight to lose. I had already played with relaxing the A1C to a steady state of 6.5 but now with LdL and total cholesterol both within range. I had also realized since the beginning of 2023, that one thing is autophagy but another thing is to have cell death. Lactic acid production from that "cyclist trainer" made cell death possibly worse. So I am increasingly saying: "it's the health of the mitochondria stupid". It's clear for me it’s less calorie, be it from carb or fat (that's from you - thank you), and with supplementation to reduce ROS. The Taurine study, as many of these studies go, is mainly for overweight people and those with blood sugar issues.

I take 2 grams first thing in water every day, I am 74 years old and think the benefits outweigh the negatives I weight train twice a week pushing hard increasing weight or reps every workout, this I find is all good, I add creatine every day also.

My vet recommended it for my dying dogs heart and he lived months longer than predicted.

Important to note that there are plenty of ways to get taurine. Diets high in meats and fish will probably have all the taurine you would need. As far as im aware, seafoods are the most abundant sources of taurine naturally. This could be one reason people in southeast Asia have such long lifespans. Plenty of taurine found naturally in their diets.

Subscribed! I'm 66 and have studied health and fitness on a daily basis for the past 30 years, learning something new on nearly a daily basis. I salute your clearly articulated narration and presentation. There are so many presenters out there that just do not speak clearly, nor present info in a logical manner. My daily supplement regimen has included taurine for over 20 years. When you hit 60, you body and mind will become more sensitive to finding the optimal nutritional balance point, aka homeostasis. I'm interested now in watching all of your presentations, and curious to know your thoughts on N-acytl-L Carnosine (which I also take).

Looking forward to the second segment on Taurine supplementation.

As always, very unbiased clear and honest explanation! Thanks! And thumb up 👍

You have the gift of balanced research synthesizing thoughts and teaching. A++!

Your channel is fast becoming one of my favorites! Thank you for the balanced way that you presented the information from the study.

You do a great job of explaining challenging concepts and you do it with charm and humor.

I’ve subscribed. Your attention to detail but cautious optimism is exactly what I’m here for. I experienced quite an unexpected potential benefit: I suffered 11 months of slight double vision in which my left eye would not come quite back to center when looking to my left and back. Just three weeks after taking two big taurine pills daily, it virtually stopped. No one can say whether it was taurine but I can’t help but make a possible connection. Thanks

I am finding taurine helps with improvement in Gallbladder and Liver health. Increased bile production, and parasite removal. Taurine is a supplement I include as part of a way of life, and do not depend on it solely, or treat it like a medication. It works synergistically, and in my experience is best used from that point of view.

I'd like to hear more about the bone growth aspect. Could this help with osteopenia, joint rehabilitation, dental health?

Why do our bodies produce less Taurine as we age? What processes are we trying to compensate for? Does simply adding more to our bodies actually fix the underlying problem?

In the chart in your video, N-Acetyltaurine (NAcT) is strongly associated with kidney disease. "NAcT is an endogenous metabolite. Biochemically, N-acetyltaurine is formed as a result of an acetylation of taurine." Alcohol metabolization in the liver is listed as the primary driver of the conversion of taurine to NAcT. Would supplementation of taurine require one to avoid alcohol? Also, many American's sufferer from non-alcoholic liver disease (from over consumption of carbohydrates). Would this also increase their risk of taurine to NAcT? If so, would we see a dramatic increase in liver and kidney disease with use of this supplement?

Just started taking it two days ago., with tuduca.I think I'm already feeling a difference... Crazy.. My legs are already feeling stronger.. My nerves are feeling a little better.. My arms feel stronger.. I'm not Even working out yet... I've been sick for over 12 yrs.. Recently started suffering from neuropathy.. My legs and feet went seriously weak.... On top of yrs of being sick with fibro or Lyme's?? I have spent yrs of trying to fix myself.. Drs can't or won't help if you don't have insurance to run all the tests .. Even with insurance it's too expensive to get healed.. I've found turkey tail and shelijet(?) helps allot then I added this stuff and really feeling a difference.. next I would like to try peptides...

This is awesome I have been taking tarine for 15 years I had a nature path to a neurotransmitter test on me and said my body was not making it and I needed to take it and it was huge cuz I suddenly calmed down Good to know that it will do all this other stuff too thanks!

Great vid! Please do one on Telomers and the anti aging process. This + DNA editing will and proper supplement nutrition and exercise will def. Increase lifespan

I added 1-2g taurine to my afternoon stack about 5yrs ago. It’s no magic bullet, but is beneficial along with other aminos.

Taurine has been on my mind for the last few years and I'm so happy to have found this video (and channel!) that expounds greatly upon my interest. I'm currently using a health drink that focus' on taurine supplementation. Personally, I do have reservations per liver issues.

Thanks! I really like when u simplified the data for us guys with a 3rd grade education , continue the good work 😊

would be cool if you made a video about bone density in general

Great video on the topic and a really fine example of how to critically think about scientific papers beyond the headlines.

Thank you! This just showed up in my RU-vid feed, and I'm so glad it did! I've been interested in and learning as much as I can about science, especially regarding health, my entire life. My education and training has not been in the science or medical field, it's one of my favorite interests. I love learning as much as I am able, it's a passion of mine. So, Geek on! The information you share will help so many people... including people who are so inclined, as I am, are able to Geek Out with you ❤ Thank you!

Your teaching style is informative and keeps one engaged 👍😎

Wow! Your analysis of the the data, pro and con, was spot on. Sadly, this type analysis is exceedingly rare

Thank you for a totally unbiased evaluation this is very refreshing, as a type 2 diabetic i think i will sit on the fence for now loved the video.

Boron and magnesium changed my life. They cured my back pain. I take them everyday. I have had zero side effects. My back was really bad. Now I'm pain free.

Wow! I am impressed! Excellent video, professionally done, well explained, etc., etc. Thank you so much for taking your valuable time to share this with us!

Many thanks Nic for a very informative video. I am 65 and started taking Taurine a few months ago.

You deserve a larger audience! Your presentation is way better than than I have come to expect!✅ I'll be frequent visitor. Thanks.

I have been taking taurine 12 grams/day for cardiac effect to stop or reverse atrial remodeling after having atrial flutter for past 3 years. My LDL has been under 100 averaging 92. Lipid profile has been totally normal in this 73 year old male.

Kudos for an exceptionally clear, well balanced presentation. I rarely watch health related programs, as so many make hyperbolic, unsubstantiated claims. The title "Nutrient of Youth" suggested this video would fit that stereotype. I would not have bothered watching except for wondering what Taurine is. Your source citation being the prestigious publication 'Science', immediately dispelled concern about baseless assertions.

I read years ago that taurine was recommended for vegans so I've been on 1,000 mg per day for years. I have a genetic disorder called PCOS which, among other things, increases my risk of diabetes, despite my super healthy lifestyle and normal weight. My latest blood tests are in the pre-diabetes range. Very discouraging. As a now-70-year-old, I will continue my healthy no-sugar diet and exercise, as well as the taurine. Thanks for this video!

Impressive interpretation and presentation. No hype, just facts. Subscribed.

Can you address the dosages that would be required to see any effect at all?

What I found with 1000mg of taurine/day was after one week 1. Libido was increased. 2. Night vision was decreased. 3. After one week the night vision component is still reduced but less than at first unless two doses are taken. During my morning walk before daybreak I look down the path to the end where a grey bench sits. Before taurine I could see this bench and surrounding trees. Now I must be half way down the path to even see the bench but it is slightly less visible at 1/4 mile in the dark depending upon lunar state. Night vision is important to me.

for me taurine boosted vo2max. Easier to train from the very first try. I'm afraid a lot of suplements has its own + and - . Its interesing for sure

I added torine to my supplement stack. I take 2h in the morning and 2 gram in the afternoon. I also added glycine 5g after every meal. What I have read I think has similar positive affect. It reduces blood glucose, it reduces inflammation etc but it works on other aspects in the body.

Subscribed. Love the way the information is presented and the presenter has amazing voice.

First time; YT sent me. I like your style and information and delivery. You’re a very I’d say innately talented, and solid teacher, your explanations are key to my staying power. And for me? I need things explained, as to why I’d do this or that, and not just the hyper excitement of new findings, but also the restraint of a physician with years of experience behind him. I got that from you. And you’re too young, lol. So thanks! Subbed and all thumbs up. 👍👍😊

Nice job, the thing with a scientific study is that it is one study. The thing that makes good science is repeatability and if results stand the test of time.

I remember similar life extensions for mice fed with GLYNAC, would love to see mice on GLYNAC and Taurine together.

Thanks Guy, I watched your video a week ago and ordered a bottle of Taurine 1000 and arrived today. I had in 2004 an auto accident and likened to a fragmented hard drive my body had something or PTST and never quite recovered. I would have good days and a lot of bad days. I ate 2 of these guys this morning and feel something good and have high hopes it continues to work. I highly recommend to any one who suffer from PTSD type of constant bad feeling. I also am 72 years old.Thank you

Great Channel with discussion of positive and negative side of supplements. If you feel unsure to use Taurine supplements try to focus on food that contain Taurine

Could the increase in bone density/increase be related to the increase in muscle strength rather than directly related to taurine?

Any opinion on why the box is red for previous kidney disease? Every comment I read says the opposite when it comes to taurine and kidney disease?

So basically it puts the body back in a growth phase, something that optimizes repair when relevant at the cost of increasing the cancer risk, that white elephant in the room, I didn't notice you speaking much about except saying that some of the choices the body makes has the property of reducing the cancer risk and taurine seems to undo those choices.

Thank you for the video. Your English is perfect and very proper. I am gonna look up the word brevity and intact in my dictionary. Thank you smart guy!

I like Red Bull. (I know it's not healthy). This led me to taurine about 5 years ago. I have arthritis in the neck which causes bad cramps and spasms. Once or twice a week I take a quarter teaspoon of taurine, fixes the problem 100%. 😎👍

I don‘t know if it plays a role but Monster Energy drink is the only soft drink I can drink without feeling bad after effects : I only feel more energized ❤ Wondering if the added Taurin has an effect on my level of inflammation…

WARNING: I started taking 6 grams of taurine each day for about 3 and a half months. After about a month I started getting a stiff neck. It kept getting worse. An X-ray shows arthritis. I looked up Taurine and arthritis & found taurine is very concentrated where there is arthritis. The studies think that is preventative. But I think perhaps the imbalance of my taurine intake will my other amino acids caused an autoimmune response. I stopped taking taurine after the 3 1/2 months and my neck has significantly improved . It is about a month now since I stopped . (I also did some physical therapy at the start of my neck problems but it didn’t help).

Best explanations of what graphs mean on each axis. So many assume we can ready graphs at a glance

I super appreciate when intelligent content is put together for all of us to consume. Just found you, now time to watch all your content! Thank you!!

After 2 minutes of listening, I gotta say you don't need to worry about prolonging your life man, you'll outlive us all.

Really good presentation. I have had some questions and concerns about the level of Taurine to continue at this later stage of life.

I like your way of explaining things. Very nice video. Keep it up, Nick 👍

All natural amino acids are left hand molecules. However, when we synthesis chemicals we often mix left and right. This mistake would drastically reduce Taurine's effectiveness. Is Taurine a left hand amino acid?

Thank you for hearing, listening to the CAll. Glad you're in the number and sharing the space at this moment in time. I love you

Taurine is a must for cats. This is the first I’m hearing of it other than for my kitties. Thank you!

Taurine is omni present in most Energy Drink that get blasted for being not healthy . 0 sugar Energy Drinks with Taurine are great in my view

I really like your analysis. You seem to look at all sides of the issue

PLEASE Reevaluate lipid profiles wellness factors with the understanding that the cholesterol issue is not supported. Taurine helps with Magnesium transport. Probably better results with multiple vitamins and chelated minerals. Taurine is a mineral chelator and a transported to improve absorption.

Fantastic! Thanks for the detail, at 52yo I’m learning new things everyday on my health and wellness journey. I’m subscribing and look forward to geeking out with you on your other videos! Thanks for posting! 🤗

Might you discuss supplementation with taurine above a certain level versus dietary intake level of taurine? ✓100 grams of scallops can have up to 827 milligrams of taurine ✓yellowfin tuna contains up to 964 milligrams of taurine per 100 grams ✓seaweed (nori) 1,300 milligrams of taurine per 100 grams Maybe this is the secret to Okinawan / Japanese longevity.

I have a genetic disorder that essentially speeds up the aging process. Taurine has literally been a lifesaver👍🎯 So grateful to see the science come out on this and match the conclusions I myself had reached. Dear friends & fam: I don't normally say this, but...I fucking told you so!

Great video. Glad this showed up in my recommendations.

I volunteer for the study , my idea for a study, where a catalyst, like Quercetin or French pine-bark extract is used to increase the effectiveness of Taurine.

Great stuff physionic. Keep up the great work 👍

🥴 I feel younger just hearing about this ... Amazing !!

Ok, hear me out. I'm 41yo, reasonably healthy male. I've just started supplementing taurine and noticed some magical things started happening! Energy levels are up, very noticeably - I used to love working out but over the last few years I've somewhat deflated, lost my edge and will to work out - straight after supplementing taurine I started to feel the urge, the tingle to hit the gym and my muscles hard again! The quality of sleep dramatically improved, especially the falling asleep aspect, which in turn seems to have started to normalise my circadian rhythm. Borderline insomnia has been my struggle as long as I can remember. I've always dreamt of becoming an early bird - maybe now I have a chance to achieve it. But wait, there's more! Most importantly of all I noticed a dramatic improvement in my RSI (forearms) and radial nerve damage in my right arm. The pain has gone from severe to barely noticeable just after a couple of days of supplementing taurine. Before, I've tried everything, all supplements (apart from the taurine) and exercises, including the "nerve flossing" exercises, with very little impact. Looking forward to seeing what comes next. Best regards to all!

Experienced a Main Coon cat of poor health; he lived 16 years although the Veterinarian had said early on, he should have already passed (Heart) shortly after his birth. The Veterinarian (U. of F.) did recommend Taurine be included in his specialized cat food. This Video went beyond my cat’s Docter’s explanation, and Buddy (Maine Coone) outlived his health disposition by more than doubling his years. Although his health rapidly declined and was put to sleep early in his last year. However, he and I enjoyed his added time. Now it is nearing my time, late but am going to start taking this additive (Taurine).

I appreciate that you tend well in the direction of evidence based science instead of opinion and bias. Thank you!

Taurine cured my anxiety / ocd / wired and tired which is caused by too much glutamine. It increases GABA. It may help some people with seizures too,

thanks for coming through man. so there are things i have to worry about. it seems good to take it. i guess we have to wonder what dosage is best to take Taurine. maybe that would make it much safer.

I think you should do a deep dive on the study. We’re all here for science, so everyone will most likely enjoy it, no?

Ive used taurine fot years sublingually. I feel it improves inflammation and immunity.

You explain things clearly. Thanks

NERD ON!!! Thanks for the balancing nuances.

Huge and remarkable if true, yet with the dosage of 1000 mg/kg body weight in Fig 1D (as well as subsequent figures), I would expect a much greater difference. It doesn’t look like the authors measured blood levels of taurine supplementation over time and the paper only answers some cursory questions of taurine mechanism, but this does leave the door open for some interesting experiments to be conducted next. Thanks for discussing it!

Great video 👏🏻 I may have skipped over a part of the video or maybe not, did you talk about the studies on kidney health when taking Taurine? I’m not sure if there are any but after taking Taurine and getting the results amped up on the benefits I read that there is deleterious effect on Kidneys, I was wondering if anyone has read about this and if it’s valid?