The Biggest Science Frauds EVER 

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"If life gives you lemons, make lemon grenades. Then throw them at your enemies and watch them explode into a cloud of citrusy doom. It's the Aperture Science way!"

Simon: “I have friends who are academics!” Simon’s academic friends: “Yeah, he’s our token “semi”-intelligent friend.” 🤣🤣🤣

More citations can mean more prestige, but it can also mean that your paper is so bad that people feel the need to correct it and then they have to cite it.

At 2:25, the difference between anesthesia and execution is a very thin line. Anyone can put people to sleep. The trick is having them wake up again!

Quick note, retracted papers arent all necessarily fraudulent. Many get retracted because of mistakes, later identified data/test procedures issues, legal complications preventing further publication, and many other reasons. But yes, fraud is, of course, one reason.

In my opinion Kevin is deliberately trying to send Simon to a speech therapist.

Mad respect for the cliff Burton shout out

Every time a writer makes Simon say the name Joaquin, an angel gets its wings.

Really thought the magic box would be about Theranos because they tried to sell a magic box 😂

To correct the editor, Simon was not thinking about execution. There are three parts to general anesthesia.

It astounds me that some people disparage science in general. My grandmother thinks going to the moon was a huge waste of time and money and I'm like, "okay, but you like velcro... right?" The other evening I was watching a docuseries on remote island volcanoes and my mother couldn't understand why scientists wanted to investigate them because "we wouldn't be able to build societies there anyway." Neither of them can think laterally :(

When I had my gallbladder out, the hospital billed more for the anesthesiologist than the surgeon. I’m fine with that. If the surgeon screws up, I get an infection. If the anesthesiologist screws up, I either wake up screaming or I don’t wake up at all.

I swear these days half the reason I watch these videos is to see if Lorelei edited them (can usually tell by the Doctor Who clips lol) and I can normally tell before the end... she's become my favourite editor on RU-vid because she's hilarious. Hope you're enjoying the specials Lorelei! Great work on the video as always.

Props to Lorelei on the editing. The memes were on point. The "we're all fucked" with Simon drinking a coke got me harder than i like to admit.

What a better way to start off the week than with a fresh Brain Blaze! And as a reminder, I can provide you access to all of my complete scripts, unedited and uncensored!

I have tea in my sinuses now thanks to the “We’re all f@#ked’” Well done😂

The anesthesiologist is literally the guy keeping you alive and not screaming in pain while the surgeon does the cutting and sewing. He's the guy who monitors your vitals, the master of all the drugs involved in the operation, the one who does all the procedures involved in reanimation if your heart stops beating (yes he's the guy who does the chest compressions and electric shock stuff), the one who pumps blood back in your body if you're bleeding profusely (while the surgeon does everything to stop the bleeding), the one who puts you to sleep before the surgery and wakes you up after etc... People tend to think surgery is all about the surgeon, but a surgeon is as useless without the anesthesiologist as without the nurses. The anesthesiologist also has at least one anesthesiologist nurse assisting him at all times. There's always at least two doctors in an operating room: the anesthesiologist and as many surgeons as needed, usually one.

Simon I’m in need of an OGBB visual to make sure Peter is okay

Everytime I hear about fake research winding up in journal articles, I have to wonder what's going on at the journals. I was faculty for years. Every year, I had to submit where my work had been cited. Every year, I did unpaid service (as most faculty do) reviewing articles submitted for publication. You're supposed to be an expert in your field.If something doesn't sound right, it's not that it's so new you don't understand it, it probably isn't right. There are also multiple reviewers per article. You look at the works cited in the article; do they say what the submitted article authors think they say? Is there a misinterpretation? Are the 'right' articles even cited? That is, there should be a traceable line from previous research to the one being reviewed. If there are a bunch of articles that don't make sense, the reviewer should be suspicious. You don't have to read each cited work, but you should darned well be familiar with most of them. You're not just given an article to review because you're a professor, but because your research is in the same field and/or you're published in the same area. So, long professor story short, for all these unsupported articles to be published in what I assume are authoritative journals (there are scams out there called 'predatory journals; another story), lots of people had to be asleep at the wheel.

Its funny, everytime Simon has a coke, i want a coke. But its only coke. Like if he has a coffee or a red bull i dont want any of those.

I run anesthesia on animals. It's terrifying. Anesthesia is very complicated and I'm constantly learning new things.

The Danny escape attempt counter made me laugh 😂

Anesthesiologists also a mixture of pain medication, sedatives and a paralytic for intubation. Paramedics and nurses will use the same for rapid sequence intubation. So you are correct that some nurses can give them. Prison guards will give the same drugs for execution as well.

Kevin, you have rapidly become my favorite writer. you have the best topics, seasoned with just the right amount of sarcasm and hate. thank you for what you do, and braving so many watch lists for our education and entertainment

Cracks me up everytime Simon does a dumb and has that silent moment of reflection 😆 🤣

What if someone else is shitting in the river up stream to where you are living??? Why are we living in the woods again?

Kevin needs a Xmas bonus down in the basement maybe a Xmas pudding and a Christmas dinner 😂😂

Thanks great video I reiterate Simon should do an entire video, having a Q&A with GPT.

This might be the best ever Simon! Mixing up surgery and executions. Please don't ever change Simon. In every case, your commentary makes my day!

15:20 made me literally lol. You can do it, Danny!

I think the arsenic bacteria one actually got a lot more interest in how bacteria actually survive around arsenic which would probably have been pretty common in early habitats for ancient life.

You don't want to make anesthesiologist angry they can paralyze you but make sure you can still feel everything!

Yes, anesthesia often includes a paralytic. For many surgeries, it would be awfully inconvenient if the patient started moving around in a sedated state. Its correct that in the hospital, it's the anesthesiologist and never the nurse that puts the patient under. Paramedics, outside of the hospital, are also able induce patients in circumstances where a conscious patient needs to have a endotracheal (breathing) tube placed immediately. Other than that, I believe critical care nurses are also able to induce patients, although I haven't asked anyone to confirm that.

Omfg love the Cliff Burton clip🥺❤️I play guitar and bas and just started getting into Cliff. One of the best there ever was

Anesthesia can be given/managed, at least in the US, by both an Anesthesiologist, who is a medical doctor, or a Nurse Anesthetist, a Registered Professional Nurse, a level equivalent to a Nurse Practitioner; you can even have both practicing at the same procedure at the same time.

@9:28 that is exactly what happened to a couple of lawyers in the USA this year, they went with what chat GPT gave them verbatim and it gave them the wrong info.

Every time I clear my throat the mesothelioma jingle goes through my mind now. 😂

That last one is a good reminder of how we can put on blinders when we want something to be true. Always question your findings before declaring it as truth. It will save you from embarrassment, and worse.

1:40 - Chapter 1 - Top of the leaderboard 2:45 - Mid roll ads 4:35 - Back to the video 12:40 - Chapter 2 - Getting loosey with the goosey 20:10 - Chapter 3 - Arsenic life

another great script and great editing.... simon wasnt bad either

Phenomenal memes today, they made me smile!

Keep trying Danny! You'll make it out soon, I'm sure

Project Panda is a bit of a wild story in its own right. The samples they tested were gathered by flying jets with catchment devices mounted on them through the mushroom cloud from the nuclear bomb, and then just high tailing it across the ocean to Berkley where there was a lab that could detect these elements....looking for something that might have a half life in the realm of a few hours.

Loving the Doctor Who call-outs! And, yes, the guy you mentioned is objectively a bell-end.

They touched briefly on the woman issue in Los Alamos in Oppenheimer. They clearly outlined at least one was there... and that Robert made sure of it and respected her.

I haven’t seen this kind of Simon before- I’ve just seen him following the script perfectly. I love this kind of Simon so much! And the video is scary as someone who relies heavily on medication 😞

Academic here, each journal has an "impact factor". For example nature (one of the top journals) is ~64 PNAS (a good journal) ~11 and you have journals that are basically pay to publish with little review with much lower impact. The higher the impact factor the better. The impact factor is how many times a journal is cited divided by the total number of articles. So a study published in nature on average will be cited 64 times for a reference. This calculation can be done for a researcher or lab or single study and the more curtains the more impactful it is in the community.

I love how sassy the memes are in this video 😁😂

Anesthesiologist keep you in a delicate state between consciousness and death. It's easy when things are going well, more technical when someone trends towards death, exceptionally more difficult when someone is nearing death before the anesthesia even begins (life saving surgies)

I spend way to much time in hospital thanks to far too many health problems to get into. But anaesthesiologists are some of my favourite doctors I've been awake for quite a few surgeries but obviously on a lot meds so I didn't feel anything. Me and the doctor were just jamming to unwritten and punk rocker to a point the main surgeon told us to shut up cause he hated those songs. It was great

Just for the record: an anaesthesiologist is a doctor, then you have a technician, who can be diploma level, or a nurse with an extra bit of study. And you nailed it - it’s the “putting you to sleep” triangle: paralytics, amnesiacs, and analgesia. 😅 sorry edit: an anaesthetic tech is not normally degree level, but they need specific papers, so nurses can do those to do that job. In ICU, we use a lot of the same drugs they use in surgery to keep you sedated and monitor the ventilator, so we actually do some of the same functions of the anaesthesiologist.

Lorelei continues to be my favorite editor! The source content is just so perfect and the variety of clips is superb. Master-class! It makes an already very interesting video that much more fun.

Lorelei … I’m sure you’ve gotten flack for it but … the mesothelioma but will always, ALWAYS, make me laugh.

"searching insult database..." 🤣🤣🤣

Editor: Lorelei Brown? Lorelei Brown was the name of a character in the TV sitcom My Favorite Martian (1963 to 1966) played by Pamela Britton. She was the ditzy landlady.

Memes leaning into simon's bionic abilities. I wonder if it's Sam or Lorelei Editing today. (edit) Definitely Lorelei. Keeep up the good work! Love the memes an in-jokes!

I just watched that documentary about Paolo Macchiarini and his fake windpipes, and OMG I felt sick in my stomach watching, the science world is so messed up it's insane. I have no ideia how someone manages to go as far as killing 5 people until someone is like "ok, maybe we should read the papers and test his findings" 🙃🙃🙃 (and to be honest, quite shocking the other doctors be like "ok it makes no scientific sense but who knows" like dude, aren't u a doctor?)

2:37 You can hear in that silence, simon realising what he just said.

Don't shit in your water source. Dig a hole and bury that, uh, shit.

An anesthesiologist's work is never done. It often begins in the prep for surgery phase when the IV is stuck in your amr. some chemicals in the drip prepare your body for the anestesia process. Well, actually, it began well before when your height and weight were taken and Dosimitry went to work calculationg how much of what would be needed. After you are wheeleed in and hooked up. you are put under. Next things to maintain that state of affairs over the course of surghery are done, sometimes for ovef 4 hours. This itself is more than one process that requires constant monitoring. Then you are prepared for recovery, which may include an amnestic and the process for bringing you back to conciousness. If it is done right, you don't even know you were out and are often quite lucid. When I had my bypass, I was told it would be a triple. When I came around I was told it was a quad. I said "What is this; by 3 get one free?"

The gaslighting worked, as today was the day I realized that I'd forgotten that this was ever called Business Blaze! 💼🔥

"Bellend" has become part of my daily Kraut-Yank Lexicon, and I blame Simon. 😂

It feels like I discover another Simon channel every week

Perfect use of skeletor😂

I’ve had brain cancer twice and Kytril was the best anti nausea medication for me while on chemo. You can only take it every 12 hours though so I did have to take Phenegran in between.

Two of my alltime favorites 'i don't understand' and 'mesothelioma'. Keep up the great work! ❤

2:00 Cliff Burton, Metallica, playing bass solo: “Anastasia, Pulling Teeth”. *chef’s kiss* 👍

My biggest science take is that bread and gravy is just really dry flour mixed with very wet flour. New blaze while I clean the swamp monster that is my bong? Sounds like a good excuse to get higher than eagle flange and drunker than a baker with autobrewery syndrome.

I'm loving the added throwback memes that are being added more and more.

Simon, I love you're reaction to you're own statements, the long pauses after you say something is hilarious, especially when you say... I'm pretty sure I'm right😂

Andrew Wakefield, definite bell-end. No question

2:35 I can see why he’d think it would be easy because all he sees is the mask getting out on and then waking up, but they have to take into account your body mass, sex, your tolerance to painkillers and sedatives, they have to keep an eye on heart rate and respiration during the procedure, not just to make sure you’re still alive, but to make sure you don’t start waking up before they’re done - which has happened to me (thankfully not a surgery). It’s not like everyone gets the same gas or same amount.

Missed opportunity for a Terminator 1 select a response/insult joke.

The Cliff Burton clip was epic, Sam you are a legend.

I have never seen a better placement for the JJJ laughing meme, great job Sam!

Informative with hilarious edits!

My dad's a nurse anesthetist and he's described it as a balancing act.

Good morning world. It's 9am here in New Zealand 🇳🇿

I received an anesthesiologists report as part of a sheaf of documents regarding a medical procedure that I had undergone. A teeny bit of fentenyl was in the cocktail. Now, I'm onnit full-time and you know what ? It feels great !

oh i so needed a new brain blaze today

Simon: You want to talk about Fraud? Here’s a subject: George Santos.

A fast-moving river is nature's bidet! 😂 That's both true and absolutely sarcastic.

This video gets a bonus for the Norm Macdonald reference. Great job!

The 5HT3 antagonists (Ondansetron, Granisetron principally) are pretty OK as anti-nauseants, however for those chemotherapies that are particularly emetogenic (HEVC - anything containing Platinum, also Dacarbazine, high-dose cyclophosphamide, and most anthracycline combinations) the current gold standard is a 5HT3 antagonist (Palonosetron) and Substance P antagonist / Neurokinin antagonist Netupitant combination (Akinzeo). The neurokinin antagonists were originally developed as potentially useful analgesics (back in the day when we thought Substance P was central to the pain pathways), but have found a completely different although excellent role as very potent anti-emetics. P.s. - if you are in the cell radiolabelling business, Dextran 70 provides a faster degree of RBC sedimentation than hydroxyethyl starch, especially using Heparin rather than ACD as an anticoagulant.

For anyone wondering, the bass solo Cliff is playing is called Anesthesia.

I watch Casual Criminalist. Simon is OFTEN thinking about executions.

I’m honestly impressed. I’ve been trying to get multiple papers published for three years and they’ve all been rejected except for 1 but they’ve kinda gone dark on me after approving me. Here’s hoping I hear back soon

Thumbs up OG Business Blaze Legions!!! Also Simon you are talking about impact factor

12:45 Sam showing why he is the ultimate editor: utilizing a scene from the MUCH more entertaining Buffy movie. He’s earned additional time out of the Blazement for a month.

Lol I've managed to be offensive to doctors and nurses at the same time....yes😂

love how simon went on a rant about joachim not being pronunced like its written fully unaware that in german it is

I love the picture popping up of the lead singer of Sabaton at 9:54 haha

1:57 All hail Cliff Burton! The song is (Anesthesia) - Pulling Teeth if anyone is unaware and curious. :)

I like it when you put the a bit of fry and Laurie parts in

I love this channel!

Acronym... Please please please never stop Simon ♥️

Hello from Oklahoma!! ✌🏻

Seriously, I end up watching these about 5 times with rewind allowance. The editor is wonderful (and is a fan of the Doctor 😂) and deserves every penny/cent/centissimo etc that Simon pays them!

Oh I’ve missed the “ I don’t understand bitch “ meme 😊