The Mechanism of Insulin Release by Pancreatic β-cells

Подписаться 358 тыс.

Просмотров 109 тыс.

50% 1

⚡ Welcome to Catalyst University! I am Kevin Tokoph, PT, DPT.
I hope you enjoy the video! Please leave a like and subscribe! 🙏
INSTAGRAM | @thecatalystuniversity
Follow me on Instagram @thecatalystuniversity for additional helpful content and for my more fun side: Pets, Workouts, Dragon Ball Z
SleepPhones® | Need to Relax? Ocean waves, ASMR, Rainstorms, and Theta Waves while you sleep with SleepPhones® at this link: www.sleepphone... - Use the Coupon Code, “CatalystRelax”, at the checkout for some awesome savings.
More details here in my new video: • Video
MERCHANDISE
Be sure to check out custom Catalyst University merchandise!
LINK | teespring.com/...
PATREON
LINK | / catalystuniversity

Опубликовано:

14 окт 2024

Ссылка:

Скачать:

Готовим ссылку...

Добавить в:

Мой плейлист

Посмотреть позже

Комментарии : 82

@normallochie7390 Год назад

This has the hardest intro I have ever seen

@xaviermagnate 2 года назад

EXTRAORDINARY on every level! Thank you for the incredible and erudite tutorial. Simply PERFECTION!

@tigerhillsupa 18 дней назад

your video has made the mechanism so simple! Compared to book reading , I would rather watch your video!

@hafsa4901 Год назад

Thanks it helped me for my cell signaling exam .

@olgakaldou1606 5 лет назад

Great video! Thank you for your efforts! I study for my physiology exams and that helped me understand and visualize the whole process! Looking forward to other videos!

@domenicafigueroa9230 3 года назад

Just what I was looking for, thank you!!

@williewonka6694 Год назад

Excellent explanations of these mechanisms. Reviewed a couple of times to understand the K+ and Ca+2 gate operations on insulation release.

@weezy224 5 месяцев назад

very nice and well explained, thank you

@noname-mm9of 3 года назад

This video is pure quality

@katefreedom9708 Год назад

Learned a lot beautiful explanation

@obscuredoblivion444 Год назад

Im always so amazed how our body works.

@imtinan7136 2 года назад

Couldn’t be easier! Thank you so much

@Velvet003 Год назад

Excellent explanation!

@erikfermin1787 Год назад

very clear explanation thank you so much

@mutuwamercyvivian5748 2 года назад

All I needed to understand... thanks

@agnieszkapodraza3083 2 года назад

Thank you so much ! Amazing work

@ShemMwangi-no8nz 3 месяца назад

easily well understood

@mahuubao Год назад

Excellent ... well done ...

@angellahnkhoma2762 Год назад

Best explanation 🤗

@mahmuterzengin614 3 года назад

Thanks a lot. Great video. Very nice explanation. I admire your job.

@inglescomcremildo6803 Год назад

That's cool man. Thank you a bunch.

@tasneemaburaiya6944 4 года назад

This really helps to make the process very clear! I have master degree presentation and this really helped me. Can you please send me references for the figures you are explaining?? I will really appreciated Thank you :)

@CatalystUniversity 4 года назад

Thank you, and I'm glad it was helpful. I can't post files here, but if you type "lehninger insulin synthesis" into Google image search, you should find these images within the first 20 images in the results.

@tasneemaburaiya6944 4 года назад

@@CatalystUniversity can I have your email if I ever have a question about anything thats rlevant to this , . I will appreciate it . Thank you and Good night

@saitdemir6677 4 года назад

@@tasneemaburaiya6944 @Catalyst University she wants your email address give it to her :)

@malikoussama6378 2 года назад

Well explained 👏 👏 👏

@leonidalekseyev3809 2 года назад

Very helpful, thanks a lot! Could you resommend a good textbook or two on Biology?

@medicalscience1528 2 года назад

What I really wanna know how beta cells detect or sense that there is glucose in blood ? Or glucose simply travel to beta cells by their own ? Please clear it. Thank you for video.

@josephboronka1734 Год назад

✔👍 perhaps through the GLUT2 transporter?

@catherinesalim3173 2 года назад

Thank you so much,

@AmirTalipov 5 месяцев назад

great, thank you!

@pranjalipranjali2751 10 месяцев назад

extraordinarily well

@marisad4079 Месяц назад

so low insulin could be due to lack of calcium influx into the cells?

@matthayden1979 Год назад

Will calcium rich food or calcium supplement help in regenerating beta cells?

@itsiremm 7 месяцев назад

THANK U SO MUCH😭💙

@nynmlg2299 3 года назад

Thank you!!

@moiez0192 2 года назад

the intro killed me

@stevenwoldesellasie4520 3 года назад

And how is the release of calcium from the smooth ER regulated?

@gordisspegel4159 4 года назад

Thank you!

@odarissantos6538 2 года назад

Around 5:36 you had mentioned that there is an increase in Potassium efflux. Did you mean Calcium Influx? I got a bit confused there.

@carolineatalley2051 2 месяца назад

I think that's what he'd meant

@stevenwoldesellasie4520 3 года назад

Even if you have moderate inhibition of potassium channels, there must be a certain minimum amount of ATP concentration needed since depolarisation is a all or nothing mechanism.

@crimpers5543 Год назад

wow that intro

@bio366geethasankar7 9 месяцев назад

🙏

@mo_nicole 7 месяцев назад

Can anyone tell me if the pancreas can suddenly stop producing insulin? I’m talking like over night or working hours? Or is it typically progressive? I’m sure many factors involved but just in general. Thank you.

@danielvalentindominguezsal2275 3 месяца назад

It's typically progressive

@medicalscience1528 2 года назад

Liked and subscribed 👍🏻 :)

@islamshihata4380 8 месяцев назад

Great

@AdegbiteStephen-zz8bl Год назад

Thanks you Dr Igudia on RU-vid for all you do in my life and my family. I went for a test today after taking the medication i ordered from Dr Igudia and I tested diabetes’s negative. Thanks doctor I will keep letting the world know about your good work sir.

@liutasx 4 года назад

So not glucose, but ATP/energy status of beta cell causes to release insulin?

@wakylaugh 4 года назад

You need glucose to produce the ATP

@liutasx 4 года назад

@@wakylaugh Beta cells can use fatty and amino acids to produce ATP, not only glucose.

@wakylaugh 4 года назад

liutasx but he’s specifically talking about GLYCOLYSIS and GLUCOSE

@iamliam6929 4 года назад

@@liutasx hey idk if still relevant but, ...try to think this way , beta oxidation is not favoured in this kind of situation when u have a lot of glucose(a lot of potential energy) ..no need for further beta oxidation..i guess its a lot more complex than this but it makes sense :D

@pedrorodrigueztube 4 года назад

So beta blockers block insulin and elevate blood glucose levels ?

@iamliam6929 4 года назад

hey man, idk if still relevant but... beta blockers have nothing to do with beta pancreatic cells (i understood that u linked these two)...beta blockers are antagonists of beta adrenergic receptors (beta1,2,3). Beta 2 receptor activation normally leads to glycogen breakdown in liver and glucagon release from alpha cell of pancreas (glucagon stimulates glucose synthesis) so therefore beta blockers can actually lower ur plasma glucose ...cheers

@pedrorodrigueztube 4 года назад

@@iamliam6929 it is said that first gen beta blockers affects all types of beta cells in all types of tissue. So by taking beta blockers you might inhibit insulin also and will lead to high glucose in blood.

@iamliam6929 4 года назад

@@pedrorodrigueztube oh okay didnt know that :) i guess i need to dig deeper :) cheers !

@pedrorodrigueztube 4 года назад

@@iamliam6929 Iam no expert either

@adelenemorrow8852 4 года назад

Really appreciate your work! Thank you!

@granderondeproductions3286 3 года назад

So, what part of this process gets broken if a person has type 1 diabetes?

@granderondeproductions3286 3 года назад

@Hemlock Cocktail I see. thank you for explaining that to me.

@josephboronka1734 Год назад

Maybe the Insulin secretion is good enough 🤔, and the 3:44 body has all it needs , so it resists and glucose goes up , and the cell just produces more and more Insulin till it maximum out 😊