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What Science ACTUALLY Says About Glucosamine & Chondroitin 

Jeffrey Peng MD
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I review Glucosamine Sulfate and Chondroitin for Joint Pain & Arthritis.
pubmed.ncbi.nlm.nih.gov/35924...
pubmed.ncbi.nlm.nih.gov/35024...
bjsm.bmj.com/content/52/3/167...
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Jeffrey Peng MD is a nonoperative orthopedist and sports medicine specialist. He created a RU-vid channel and blog to translate cutting edge medical knowledge and clinical research to benefit all those looking to live an active and healthy lifestyle. He focuses on maximizing non-surgical treatments for sports injuries and orthopedic conditions. He specializes in using orthobiologics and ultrasound guided minimally invasive techniques to treat osteoarthritis, tendinopathies, and musculoskeletal disorders.
Dr. Peng is board certified in sports medicine and family medicine. He completed residency with the Stanford family medicine residency program and completed his sports medicine training with the Stanford primary care sports medicine fellowship in San Jose. He is an active faculty member for both programs and is excited about training the next generation of physicians.
Dr. Peng’s sports medicine clinic is located in Campbell, California.
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25 янв 2023

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Комментарии : 584   
@garryjistel280
@garryjistel280 9 месяцев назад
I have been taking glucosamine and condroitin for 40 years. It has kept me on my feet and avoid knee replacement. I am not going to stop it now. I was diagnosed with osteoarthritis in my mid 20's. I am now 68.
@tamilkalakkalkitchen623
@tamilkalakkalkitchen623 8 месяцев назад
Is it true ?? Are you able to manage this situation for 40 years...
@phlotographer
@phlotographer 8 месяцев назад
I have been using 1500 MG Glucosamine Sulfate from Costco for about half the time of your usage. It was recommended by a friend and I was told to use it for at least 2 weeks. Even prior to that the severe pain I had with my R achiles tendon was eliminated. However, when stopping usage, the pain immediately returned and so I have never stopped using the product and likely never will but I might do another test to see if the issue has totally disappeared over the years.
@tresahines9862
@tresahines9862 8 месяцев назад
Wow thank you for that information, I don't want surgery
@leisurely6711
@leisurely6711 7 месяцев назад
Have you gotten recent mri it ct scans? I wonder if there was any improvement
@HepCatJack
@HepCatJack 6 месяцев назад
Some supplements also include Elk Velvet Antler (Cervus Elaphus Canadensis) and Devil's claw. Others have white willow bark, Boswellia serrata extract, Boswellic acid, Lumanite, Selenium, Maganese, Pantothenic acid and collagen.
@artwise1415
@artwise1415 5 месяцев назад
I'm 73 years old. I don't have arthritis. I run. I'm physically active. I do take Glucosamine and chondroitin. My study is my aging body. When I don't take it for a month or two my knees and hips hurt and keep me from running and even from long walks. When I get back on the glucosamine and chondroitin, after a few weeks the pain diminishes to no pain at all. I can sprint, top speed, the joy of flying on my feet. I feel good in my body. It feels great to feel good. That's my personal research. Onward.
@richardf911
@richardf911 4 месяца назад
I've heard similar stories from a number of runners. Glucosamine works. Chondroitin is unnecessary.
@heleneikerenkotter2950
@heleneikerenkotter2950 3 месяца назад
I would never take this supplement as a solo. They work better in combination. The better supplements come in combination and made with Glucosamine sulfate and Chondroitin sulfate and not Glucosamine and Chondroitin hydrochloride . These are not drugs and represent the vital structure of joint tissue itself. It also promotes resiliency of other flexible tissue such as skin , arteries ,veins and heart valves. This is information found on the container of my supplement and the maker does not mess with supplements that are useless. He does years of studies before he makes the product. My husband and I both take and notice a difference when we stop. If you are allergic to the shells of shellfish ( shrimp, crab and crawfish ) do not take. Look at most studies that discourage supplements and encourage OTC or steroid injection with jaundiced eye. You have to take this supplement for a period of time to notice a difference. This is not a quick fix. This is not instant pain relief and temporary . It takes time to ruin joints and it takes time for them to heal and repair.
@lynamor2959
@lynamor2959 2 месяца назад
Amen! 🙌💯💪
@a.scotth.9955
@a.scotth.9955 2 месяца назад
My mother took it and eventually was pain free. I have arthritis in my thumb joint that joins my rest in one hand and in the middle of my hand to mt wtist in the other hand. I have arthritic damaged several fingers. Wonder if it would work for these locations. Don't see why not.
@sailingaeolus
@sailingaeolus 2 месяца назад
Same for me but I'm mid 50s.
@digital.mente.
@digital.mente. Год назад
My own totally non scientific study with my own knees is that the supplement I take with glucosamine, chondroitin, collagen, msm, hyaluronic acid and a few vitamins means no pain in my knees. When I don't take it for a couple of days the pain comes back. You have to try different brands to see which works for you.
@JeffreyPengMD
@JeffreyPengMD Год назад
Thanks for sharing your experiences!
@scotchbarrel4429
@scotchbarrel4429 Год назад
I just checked my glucosamine supplement, and bloody hell, there's no chondroitin in it 😂 Great vid, had to change the filter to recent to pickup this new update, otherwise first results are vids from 2 - 6yrs ago, and all consensus on the skeptical side, which didn't feel to good, considering I'm taking this stuff, but my man has reassured me that I'm on the right track, just gotta find one that includes chondroitin.
@malihahaque3710
@malihahaque3710 Год назад
Any side effects ?
@digital.mente.
@digital.mente. Год назад
@@malihahaque3710 For me none that I have noticed.
@holycrapfreakinsweet
@holycrapfreakinsweet Год назад
is there any way for us to eventually overcome the dependency with supplements? like sure, I'd want to take them on for a certain amount of time, but not ALL OF THE TIME. that to me is just not helping.
@phillipoleary2532
@phillipoleary2532 6 месяцев назад
Glucosamine alone worked for me. At age fifty was told both knees needed replacement and I had severe pain. Glucosamine was recommended and now at age eighty nearing eighty one am still running upstairs. No pain, no grating, no locking for thirty years. Only addition was MSM at age seventy.
@rit20095
@rit20095 4 месяца назад
Great to hear that. I have been diagnosed with osteoarthritis of knee
@matterafact
@matterafact 28 дней назад
What brand my friend
@phillipoleary2532
@phillipoleary2532 28 дней назад
No particular brand just Glucosamine 1000mg twice a day, told just need once a day, but if it works why change it? If you are not vegetarian can get it with chondroitin, which is I’m told especially good.
@tarared7668
@tarared7668 14 дней назад
I started taking NOW glucosamine only 3 days ago for my shoulder bursitis. How long for the medicine to take effect on my body?
@helendy2743
@helendy2743 11 дней назад
Would you mind what brand you're taking...many thanks God bless.
@martinpolach1330
@martinpolach1330 Год назад
I will be 77 this summer .. I still xc and down hill ski….I ride a mt bike ….I have been taking glucosamine and chondroitin for more than 20 yrs … I’m VERY fortunate that I don’t have joint issues ..!! Studies or no…but it works for me …
@islandbirdw
@islandbirdw 5 месяцев назад
Your presentation was clear concise and easy to understand. As a wellness nurse I firmly believe knowledge is the key to helping people engage in pursuing healthy sustainable habits over a lifetime. People generally will be willing to make positive lifestyle changes if they can see benefits early in the course of any potential illness.
@somerset6646
@somerset6646 10 месяцев назад
I was skeptical, but I recently started taking glucosamine, chondroitin, MSM, and it has helped my knee pain and overall aches. I take the triple strength.
@Pellican516
@Pellican516 5 месяцев назад
What is the triple strength
@isaacelone3699
@isaacelone3699 3 месяца назад
​@@Pellican516 probably 3 times more than the usual dosage sold on the market?
@nexxterra
@nexxterra 9 месяцев назад
I love how the study says "in the short term" I have never been under the impression that these were beneficial unless taken for a while...
@heleneikerenkotter2950
@heleneikerenkotter2950 2 месяца назад
This is not a supplement that works short term. It takes time for it to work to feel a difference. It is a long term supplement. It took a long time to develop worn painful joints and it takes time for Glucosamine, Chondroitin and MSM to help in the healing process. We have become a society of instant gratification. The body heals but not in an instant. An ounce of preventation is worth a pound of cure . Look at medical studies with a jaundiced eye. Who is sponsoring the study?
@phillipoleary2532
@phillipoleary2532 28 дней назад
Yes! I were late in ordering my supply once, and in just over a week felt the ache coming back.
@CorvetteLife
@CorvetteLife 2 месяца назад
Everytime I stop taking glucosamine my knees hurt
@MyNigellus
@MyNigellus Год назад
Thank you very much for tackling this topic. Very useful for an average everyday user
@JeffreyPengMD
@JeffreyPengMD Год назад
Thanks for commenting!
@MrLeedebt
@MrLeedebt 10 месяцев назад
For me, glucosamine was a miracle. But probably not for everyone. I started a job delivering meat in my 50's. I would jump off the back of the truck, trying to give the impression I was young again. After a few months, my hand and knee joints were extremely stiff and painful in the morning when I woke up. I started taking glucosamine and it brought immediate relief. Because I had worked these joints for only a few months, maybe it would be different for say a carpet layer or bricklayer, who may have done it all their lives. I kept taking them, even after leaving the job after 10 months. After three years I changed brands and it seemed to produce blood thinning and low blood pressure, so I ceased taking the glucosamine. Amazingly, I felt as good as I did prior to doing the job.
@BillyG869
@BillyG869 5 месяцев назад
In 1993 my wife and got rear ended by a truck on the freeway. After that my neck was trashed, so painful it literally limited me to muscle relanta and pain pills. Months after doctors, orthopedic surgeons and eventually chiropractors. Then I started taking a very heavy does of glucosamine/chondroitin. It took a few months to take hold, but eventually I believe my cartilage became more functional and possibly repaired itself. That is a fact and it made me functional once again. I’m now 77 work hard and take little meds. If I were to sustain another damaged joint, I would immediately turn to this supplement once again. It takes a steady intake of a sizable dose, and it takes several months to recognize its effects. See for yourself…
@team2mom805
@team2mom805 26 дней назад
Which brand?
@67daltonknox
@67daltonknox 6 месяцев назад
In my late 40s I had knee pain hiking and skiing. I even took up scuba so I would have a sport if my knees got worse. I also started G&C daily. It took a couple of years, but I was able to stop using neoprene compression on my knees. Now 76, my knees are fine and I'm still hiking and skiing, yes and taking G&C.
@garygauthier1551
@garygauthier1551 6 месяцев назад
I also have been taking glucosamine and chondroitin with MSM since 1998 ! At that time I was suffering with pain and stiffness in my right hip, my family doctor ordered a X-ray and found that I had moderate to severe joint degenaration in my hip. He suggested that I could try glucosamine and chondroitin with MSM. I also would see Chiropractors for neck & hip adjustments. After about 3 weeks I could feel my mobility had improved as well much less pain . Not only did I get improvement in my hip but also my neck issues disappeared. Just to mention that Veterinarians also prescribe glucosamine and chondroitin to horses & dogs that have mobility problems where noticeable improvement is seen ! One more thing that I think needs to be said is that glucosamine and chondroitin won't work if your joint is bone to bone.
@annpringle8219
@annpringle8219 Год назад
All your videos are great! Also glucosamine works for me and my knee pain.
@Southprong59
@Southprong59 5 месяцев назад
I have a bad case of osteoarthritis in my knee and took Glucosamine & Chondroitin pills for approximately 30 years and it helped somewhat. Then I switched to a liquid Glucosamine & Chondroitin approximately 18 years ago and it made a big difference. I experimented a couple of times by stopping my intake of Glucosamine & Chondroitin for 3-4 days and my pain increased. Obviously, you body absorbs liquids more readily than tablet forms; if you use Glucosamine & Chondroitin, I highly recommend trying the liquid form.
@theresahenry4936
@theresahenry4936 5 месяцев назад
😢
@Pellican516
@Pellican516 5 месяцев назад
What brand?
@Southprong59
@Southprong59 4 месяца назад
@@Pellican516 Nature's Way Joint Movement Glucosamine, Extra Strength - each serving contains 2000mg Glucosamine, 1200 mg Condroitin, msm, and vitamin D3. I purchased mine online through Vitacost. I took 3-3.5 teaspoons every day. You may want to start out with a little heavier daily dose for the first week to get it into your system and back of to 3 full teaspoons a day. I also take psyllium husk every day and mixed the liquid Glucosamine and water with my powdered psyllium husk. It doesn't taste bad; you could take it by itself or mixed with water or juice.
@RobertBee-fs8hv
@RobertBee-fs8hv 2 месяца назад
Never heard of liquid form
@Magstar757
@Magstar757 Месяц назад
How's it taste? Lol
@mjanebautista9477
@mjanebautista9477 7 месяцев назад
Dr.Peng, thank you so much to your such a good information...
@joecook8352
@joecook8352 6 месяцев назад
In my early thirties my elbows and knees would get horribly stiff and painful, I saw a 60 minutes show about msm, glucosamine and chondroitin and there were several older people talking about there experience with it, this was in the late eighties. I started taking it and it helped tremendously. I’ve taken them ever since and I’m 64 now. It worked for me. I started taking a prescription nsaid for arthritis several years ago in addition to the supplements because as I got older I got stiffer and it hasn’t helped near as much as when I first took the supplements
@erdemakgus4339
@erdemakgus4339 Месяц назад
@joecook8352 I would like to get your opinion on the subject of GLUCOSamine. If you have an Instagram account, is it possible to write and share it here?
@venenareligioest410
@venenareligioest410 7 месяцев назад
I remember reading an academic paper which broadly said that daily Glucosamine with chondrites was as effective as ibuprofen at releasing pain. With the added benefit that the analgesic effects did not reduce over time, as Ibuprofen does.
@triston5540
@triston5540 7 месяцев назад
Great video! I have psoriatic arthritis. I’m on a biologic. I also have developed chondromalacia patella. These supplements I assume are tested by themselves not with any added rehab exercises. My hypothesis is that combination of these with a proper workout plan designed to promote cartilage health might increase the rapidity and total gains seen in the injury.
@voxpopuli348
@voxpopuli348 6 месяцев назад
I am 66. I started taking G & C in the 90s when I was still doing ballet. I kept taking it. I still do yoga, hiking, weight training, biking. I plant to keep taking it to stay off meds and nsaids. I also take turmuric and hyaloronic acid for my joints and ligaments.
@armerwillenbring4732
@armerwillenbring4732 11 месяцев назад
Several years ago my left knee hurt so much I couldn't go up stairs. I saw a knee surgeon who said nothing can be done and I should schedule knee replacement. I asked to have a PT appointment. He said 90% of my knee pain would go away in 3 months if I did the ankle and hip exercises he recommended. I did and my knees are still pain free. I use Glucosamine and MSM just for insurance. I regularly do the ankle and hip exercises. My hips and ankles were extremely weak before doing the exercises. Bottom line, define the problem before scheduling treatment.
@jondowling720
@jondowling720 7 месяцев назад
Be very interested to know exactly which exercises you were prescribed if you don’t mind. Thank you
@debritukidane8163
@debritukidane8163 5 месяцев назад
😅
@pohlianquek2580
@pohlianquek2580 28 дней назад
Any video link on the exercises? Can pls share? Tq
@christianclavel216
@christianclavel216 12 дней назад
Can you describe those ankle and hip exercises, please?
@00708046
@00708046 5 месяцев назад
My experience taking Condroitin and glucosamine (g & c)together took time (several months ) but performed 3 repairs for me . 1/ I had a tear in my miniscus (knee) causing clicking and locking up with pain . 2/ My big toe was locking up and bending my foot in normal or quick walking was very painful . 3/ I tore a tendon in my little finger knuckle . By taking g & c 2 times per day for 4 months my toe suddenly made a loud click . I exercised it back an forth further clicking . I was able to walk and run again without restriction and pain . My knee stopped locking up and clicking after 6 months . I stopped taking my 2 doses and my toe locked up again after 2 months so I took g & c again and it disappeared in days . I would take g & c for 2 days whenever my toe would lock up . My knee remained healthy for nearly 11 years when after kneeling on a hard floor for 5 minutes doing repairs I acquired a new clicking not miniscus but more like a tendon that was sliding out of its normal place and rubbing badly . Im working on that with g & c and limiting the incorrect sliding by using elastic bandage when exercising now . I also had the same issue in my little finger knuckle . I would bend it but could not straighten it . I wrapped it to keep the tendon from sliding to the side of the knuckle and took g&c and in 2 months regained normal function . Glucosamine with Chondroitin has helped me fix tendon /ligament damage , arthitic joint lock (big toe) and repaired a torn miniscus in my knee so far . I would say that it has really helped make repairs in my body . After its already in my system , I only take it when joint damage occurs for brief periods . It seems to work for a few months after . I feel that it is helping the damage to reattach itself and mend back to its normal .
@ishitasolanki2422
@ishitasolanki2422 4 месяца назад
Thank you for sharing
@74747Kyle
@74747Kyle 28 дней назад
what was your dosage? same or more than recommended in this video?
@readthebook55
@readthebook55 Год назад
Thanks for this helpful information.
@JeffreyPengMD
@JeffreyPengMD Год назад
You're welcome!
@marilynjackson5752
@marilynjackson5752 5 месяцев назад
Thank you so much. I'm starting this today.
@etsout
@etsout 2 месяца назад
They've helped my pain greatly.
@bestsk8eva
@bestsk8eva Год назад
Thank you Dr Peng for the info 🙏I'm your new subbed!!!!
@JeffreyPengMD
@JeffreyPengMD Год назад
Welcome! Thanks for commenting!
@fractalizedspiritz
@fractalizedspiritz 22 дня назад
Dr. Peng is absolute BEST 🎉 😊
@paulmaglio9254
@paulmaglio9254 Год назад
I take Amlodipine. That and my Don Joy unloader brace are total game changers for me.
@maluell738
@maluell738 Год назад
Thank you very much Dr. Peng for the very useful lecture. From my own experience Glucosamine /Chondroitin as long term supplement helped me in summer months. Unfortunately, I suffer from extreme pain during Autumn/Winter season. So I tried with Hyaluron injection once a week all in all 5x to which the Orthopedic told me I can have up to 10 injections yearly. To date I have none or just tolerable pain during Autumn/Winter time.And that saved me to date from having artificial knee joint.
@JeffreyPengMD
@JeffreyPengMD Год назад
Awesome, thanks for sharing
@maluell738
@maluell738 Год назад
@@JeffreyPengMD I thank you Dr. Peng. I gained additional knowledge following your Vlogs. 👍👏
@michaelcale272
@michaelcale272 8 месяцев назад
It appears that this helps my wife greatly in regard to joint pain
@michaelstagar525
@michaelstagar525 Год назад
Excellent stats-peer review!
@JeffreyPengMD
@JeffreyPengMD Год назад
Glad you liked it!
@sionitacarnen9053
@sionitacarnen9053 Год назад
Thanks immensely this beneficial video. Helpful . ❤
@JeffreyPengMD
@JeffreyPengMD Год назад
Glad it was helpful!
@josephabdilla1383
@josephabdilla1383 Год назад
Thanks Very helpful
@edwinthomas618
@edwinthomas618 2 месяца назад
It works for me as i had Hip Flexor pain. Thank God I found this miracle 😊
@StephenfromChch
@StephenfromChch Год назад
Very helpful.
@theBarracuda_
@theBarracuda_ Год назад
What about MSM, hyaluronic acid does it help with shoulder pain?
@user-ff9yk7ik2n
@user-ff9yk7ik2n 7 месяцев назад
As suggested the "multi model approach" in your other video, will Glucosamine & Chondroitin work fine along with PRP injections?
@nealdickman5897
@nealdickman5897 Месяц назад
I agree. More studies need to be done about whether Glucosomine and Chondrotin is an effective sopplement to help hip, knee and other joint pain.
@jeanwang2475
@jeanwang2475 10 месяцев назад
Hi Dr. Peng, I'm 61 now, after I seen the video, I'm curious to know if it's the right thing for me to take. When I go up or down the stairs, my knees are painful, and as I walked too long it's also in pain
@michaelh2797
@michaelh2797 Год назад
I agree with digital.mente. I've been taking Osteo Bi Flex for years. I've tried other brands when the store was out, but they didn't work as well. And if I run out, I can really feel it!
@JeffreyPengMD
@JeffreyPengMD Год назад
Glad you found something that works for you!
@stevec8861
@stevec8861 7 месяцев назад
Been taking Osteo Bi-Flex or generic triple strength equivalent for decades after osteoarthritis started in my hands in early 40s. Works great. However, I take 2-3X what label says (2 pills per meal vs. label dose of 2 pills per day with food), which is also 2-3X dose that doc here suggested near end of video. At lower dose, my joint pain quickly returns.
@sable2146
@sable2146 6 месяцев назад
4:13 started taking a glucosamine and chondroitin for joint achiness a few years back and definitely noticed they have a delayed which is easy to overlook both going on and coming off (about effect 3-5 days for me). That these also act to address inflammation helps me to put in perspective why they work for me.
@lopezb
@lopezb 6 месяцев назад
Yes, agreed. G and C with HA and collagen, the last 2x-day. Right hip pain almost gone. Still cant sit lotus position, but now I walk 40 min/ day with no pain. Initially 1 year ago I couldn't walk 1 step w/o pain, and was taking acitaminophen to sleep- which is terrible for liver.
@rocketmoonshine9205
@rocketmoonshine9205 11 месяцев назад
Hi, doc. I saw a few yt videos claim glucosamine spikes our blood levels. Is it true?
@serenity8475
@serenity8475 Год назад
Thank you for your research and all you do to inform us. YOU ROCK! 🙌 BTW: I have been taking it for awhile now and it is deff God sent🙏🙏🙏
@JeffreyPengMD
@JeffreyPengMD Год назад
Thanks for commenting!
@Desperado3248
@Desperado3248 6 месяцев назад
I was skeptical at first, as a physician. I tried a short course of Glucosamine / Chondroitin in the past with little relief. I had been active, going to gym, hiking , martial arts and work. Sudden onset of arthritis in my k red was extremely painful. Tried nsaids, then knee injections with steroid once then two injections with hyaluroninase gel. First gave some improvement. Wore off in a few weeks. Second was not terribly successful, needed, nsaid. Started combination Glucosamine/Chondroitin and relief started in about 3 weeks, and is better entering my second month. I am walking, with my dog which was difficult, not getting pain at rest bit driving, can do more squats and horse stance posture workouts , and able to perform martial arts kicking again. A study looking at poor response from gel with addition of Glucosamine/Chondtoitin. I was looking at knee replacements , which now do not appear to be necessary. I will follow up with repeat k we c rays to see what status of arthritis changes are
@Sirrehpotsirch
@Sirrehpotsirch 2 месяца назад
I'm encouraged by your post! It's been four months. Care to report on your progress? Still positive about G and C? Thanks.
@krefcenz
@krefcenz Год назад
Great video. It’s really helpful to get the most up-to-date studies. I was wondering if you could do a review on a recent treatment for the arthritis call GAE. Genicular artery embolization. It is a technique developed in Japan, where they insert a catheter into your artery and inject a dye to pen point inflammation inside the knee joint. Then they release small particles to block the arteries, feeding the vascularization. some of the data coming out of UCLA. Impressive up to three years. I was just wondering if you had any thoughts. I’m currently doing PRP with hyaluronic acid injections staggered. I’m wondering if this new GAE could be an adjunct for me. Thanks
@JeffreyPengMD
@JeffreyPengMD Год назад
Genicular artery embolization and genicular nerve ablations are promising treatments but need to be studied more. These would be more for symptomatic relief and would not have the disease modifying effects (to my knowledge) that PRP may potentially have. I think it's an option worth exploring if other treatments have not worked and someone does not want a knee replacement surgery. My go to treatments right now include a combination of some or all of the following: diet, exercise (cardio+strength), PRP injections, supplements, and potentially trigger point injections if myofascial trigger points are present.
@megakwong6822
@megakwong6822 Год назад
@@JeffreyPengMD 7:25 😊
@gcea123
@gcea123 Год назад
My own independent study over past 10 + years. Glucosamine Chondroitin MSM helped my knees but not my hip.
@SEATTLEPOSEIDON32
@SEATTLEPOSEIDON32 23 дня назад
What are the best brands
@newyorkguy158
@newyorkguy158 Год назад
My story is interesting. I was developing OA in my right hip from the mid 1990's on, but I thought it was a muscle problem. The pain was never in the hip, but in the inner thigh. By 2001, I was in severe pain and limping badly. A rheumatologist diagnosed mild to moderate OA and said I would need a hip replacement within 5 years. He asked me if I wanted a referral to a surgeon. I told him that I had just started to take glucosamine and wanted to see if it would work. Within a week of taking it, my pain was totally gone in all normal activities, sitting, walking, standing and sleeping. For the next 14-15 years, glucosamine worked for me, but not all brands. For example, the CVS brand did not work. During this entire period, I only experienced pain infrequently and then only for one to a few minutes. I felt normal. I would often sprint to catch a bus or race down the stairs to catch a train with no pain. I didn't always take glucosamine with chondroitin. Often, I took glucosamine by itself and it worked very well. I concluded that chondroitin was of no help for pain. Some of the products had proprietary ingredients like bromelain and other anti-inflammatories, but not all. I can't judge the effectiveness of the proprietary formulas, since they all contained glucosamine, 1500 mgs. The form of glucosamine did not matter. I want to emphasize that brand mattered. Glucosamine is a large molecule and you need a formulation that can be absorbed into the joint. You have to try things. My advice is to not go cheap. Some of the better products can run $40-50/month, but some in the $18-25 range worked equally well. There are often 2 for 1 sales with some products. Some products worked for a period of time like 2-3 years, then began to lose effectiveness. When that happened, I switched to other products and was lucky that several brands worked very well. After 14 years, I started to get some pain at times and none of the glucosamine products were left to try. I knew that I was going to need a hip replacement. I started to play sports again and sure enough I found myself in severe pain again, with no safe product to take. I got lucky though. I learned about hip resurfacing, a surgery in which the arthritis is fixed without removing the hip. I still have my original hip and it's strong enough to play any sport. I haven't had any pain since the surgery was healed. That was in 2018. Glucosamine can definitely work, though not necessarily for everyone, but you need to experiment with the brand. My experience was not unique. Also, it may work for the hip but not the knee, or vv. I would definitely do the exercises that Dr. Peng is demonstrating, and others. Thanks to Dr. Peng for this excellent video.
@narenmenon6906
@narenmenon6906 10 месяцев назад
You must be using the "sulfate" form of the two. I also take MSM.
@fatoomgierdien110
@fatoomgierdien110 11 месяцев назад
Thanks for a great video. 👌🙏🤲♥️
@narenmenon6906
@narenmenon6906 10 месяцев назад
Did they use the "sulfate" form? I have not taken "pain killers" in many years.
@merissatolentino5317
@merissatolentino5317 11 месяцев назад
Hello Dr. how to take glucosamine &chodroitin? How many dosage,
@rameshnamdhe979
@rameshnamdhe979 Год назад
Thanks for important information
@JeffreyPengMD
@JeffreyPengMD Год назад
Welcome!
@darioalexander2333
@darioalexander2333 Год назад
what brand can you recommend?
@mwilliams-castillo9609
@mwilliams-castillo9609 Год назад
Great info thanks for sharing , my doctor told me to use that
@JeffreyPengMD
@JeffreyPengMD Год назад
Glad it was helpful!
@boonkailee8237
@boonkailee8237 8 месяцев назад
Hi doctor, please advise can i take glucosamine (include MSM & chondroitin) and boswellia together?
@SS-jb8wj
@SS-jb8wj 6 месяцев назад
I knew I had arthritis in my knees and the specialist said I would need a knee replacement down the track. In February 23 I started weight lift training. I now have no pain in my knees and I have ditched the cane. The replacement diagnosis 10 years ago. The weight lifting has built up the muscles around the knees supports the knees.
@user-sh8pp1zu4e
@user-sh8pp1zu4e 5 месяцев назад
Kindly advice me wherel🎉 to buy these products and how much is the cost all.
@dcspangler8025
@dcspangler8025 9 месяцев назад
Thank you for this post. I see that, along with the Glucosamine/Condroitin (G/C) some combinations include Methylsulfonylmethane (MSM). So how does this alter the equation? The majority of these supplements are manufactured using shellfish. There are some that are shellfish free, created by fermentation, I believe of corn. Further, what roll do GMO foods play? Both in causing inflammation in the first place and how the supplements manufactured with them differ in outcomes. Lastly, what about all the "other" ingredients? Magnesium stearate. stearic acid, etc. and how could they possibly alter the findings?
@thebrowns5337
@thebrowns5337 6 месяцев назад
Microplastics and particle pollution - something we all have and cannot limit exposure to, lead to chronic inflamation. These have been found in umbilical cords so pass from mothers lungs into babies blood. We are setting ourselves up for shorter lives with more suffering. Ditching plastic and fossil fuels is needed to help our grandchildren.
@jakobw135
@jakobw135 3 месяца назад
Which makes of glucosamine with chondroitin are considered reliable?
@shrinandan3458
@shrinandan3458 Год назад
Dr. Peng, Thanks for a very informative video. My personal experience is that the two meds when combined with MSM are very beneficial. I'm a 78 year old male with a family history of osteoarthritis. MSM definitely adds to the effectiveness. More studies should be done with the trifecta. I am living proof that it works.
@JeffreyPengMD
@JeffreyPengMD Год назад
Thanks for sharing
@kenhoward3512
@kenhoward3512 10 месяцев назад
And the next question would be whether the chondroitin could be supplanted by MSM? I've been taking glucosamine with MSM for 23 years. As always: "More studies are needed..."
@revathik9225
@revathik9225 7 месяцев назад
@shrinandan3458 Which brands of glucosamine and MSM do you use?
@teammomshie6390
@teammomshie6390 11 месяцев назад
Is it safe to take for a person who have history of an ulcer?
@lynettamurdoch5443
@lynettamurdoch5443 7 месяцев назад
I used to take the combined glucosamine/chondroitin, but then read that the one of them - I don’t remember which one - made no difference in studies so I quit and started taking MSM/chondroitin(?). Eventually, I started taking only the MSM. I really don’t notice much difference with any of the combinations - or when used alone and may quit. I do take the fish oil, or krill oil. I think it helps - but mostly, my first noticeable difference was in my thinking/brain. Lately, I’ve discovered red light therapy and I’ve been using a band that wraps around my back, hip or knees, and recently, my shoulder. It has made the most noticeable difference.
@tabathv1
@tabathv1 2 месяца назад
I have been taking them since my thirty’s to avoid having problems as my mother suffered from arthritis. I’m nearly 60 and gave to say my joints are in good condition for my age
@raymondlanier1112
@raymondlanier1112 5 месяцев назад
This supplement saved my life
@docJamesE1318
@docJamesE1318 Месяц назад
Dr Peng thank you for your concise analysis. Joint pain relief outside of Opioids is necessary what is your recommendation. Many Arthritic and chronic joint pain patients are in need of something that is greater than placebo. Let me know.
@RubinMarch-kb2ih
@RubinMarch-kb2ih 23 дня назад
We're can I found this product I'm in very bad pain with the atritus
@shunhingengco1171
@shunhingengco1171 9 месяцев назад
what's your opinion about glucosamine chondroitin msm CREAM? any good?
@tomshady3530
@tomshady3530 5 месяцев назад
no mention of MSM or zinc, necessary for joint formation?
@briansmale5457
@briansmale5457 10 месяцев назад
I've tried just about everything known to Man without much success, i then tried Green Lipped Mussel from NZ & have found a great improvement :) I gave everything i tried 12 weeks & if i didn't feel any improvement i moved on to another supplement, the green lipped musssel showed improvement with in a few weeks. I've been taking it for about 2 years now & i have to say i'm really impressed with the results.
@jakobw135
@jakobw135 3 месяца назад
Is the combination of glucosamine with chondroitin considered a chemical supplemental form of SHARK CARTILAGE? Has the above been found to regrow the missing cartilage from the affected joints?
@MadDawg-bp5wt
@MadDawg-bp5wt 6 месяцев назад
The first study mentions was has no effect on 'short term' pain and function, the other studies appear to look at a longer view .... glucosamine & chondroitin is a long term play. After years of knee pain (not arthritis) it took a few months of glucosamine and chondroitin for the pain to leave, and function improve.
@ZerikonVids
@ZerikonVids Месяц назад
Can it help me with my hip impingement and SLAP recovery?
@robohippy
@robohippy 5 месяцев назад
Prior to getting bilateral hip replacement and one knee replacement, I tried several different brands of each of clucosamine and chondritin, and as far as I could tell, they didn't do anything to relieving joint pain. It was long enough ago that I don't remember if I tried them together. There could be multiple reasons for them not working, including how severe my issues were.
@wallacegrommet9343
@wallacegrommet9343 6 месяцев назад
Do we have a mechanism of action that reveals the improvement in cartilage quality and joint space ?
@ephtamagagula8402
@ephtamagagula8402 20 дней назад
Is it for knee joints only?
@user-fh4xq2ig7z
@user-fh4xq2ig7z 6 месяцев назад
30 years ago I tore my ACL and got a classic bucket handle meniscus tear which was shaved smooth. Surgeon warned me I would have osteoarthritis there within 20 years. At year 19, the grinding started (great prediction by surgeon!). After confirming the arthritis with my doctor, I started taking glucosamine and chondrointin, but at 1/2 the recommended dosage. Within 6 months, the grinding went away and stayed quiet for 8 years. I did stop running (switched to cycling) and high impact exercises (I now teach indoor cycling and pilates). I did an accidental experiment when I tried to save money by buying gluchosamine without the chondrointin. Within 2 weeks, I had sharp pains start, so I added the chondrointin back, and the pain diminished within a month. I have now doubled my dose (which is the normal recommended daily dose) to maintain relatively pain-free living (as long as I avoid fast movements and high impacts). The combo really works! Are higher dosages than the recommended daily dosage safe?
@user-sh8pp1zu4e
@user-sh8pp1zu4e 5 месяцев назад
Where to buy this glucosamine and chondroitin in pharmacies and if not how to order it. Thnks
@JSWilliamssr
@JSWilliamssr 8 месяцев назад
That study is completely wrong. My Basset Hound has arthritis and nearly could not walk. We started giving her glucosamine & condroitin and she improved on the very first day. (We didn't tell her what it was, so no placebo effect :) ). She has been taking it for about 3 months and her improvement has been consistent and dramatic. She is running again.
@phillipoleary2532
@phillipoleary2532 28 дней назад
In Britain the health authority declared its effects to be only as a placebo. My first thought was how does that explain its effects on animals?
@abradfordajb
@abradfordajb Год назад
I'm presently using a product from Solgar which combines, in 3 daily tablets, the recommended mg levels of these two nutrients, integrated with 1,500 mg MSM & 300 mg of their formulation of "Biocell Collagen II" (180 mg Hydrolyzed Collagen II, 48 mg Chondroitin Sulfate, 30 mg Hyaluronic Acid). I also drink a daily scoop of a collagen peptide powder mixed in water. My objective is focused on rebuilding cartilage rather than simply reduction in pain. Knee cartilage destruction results in damage to the meniscus. In theory the meniscus can heal, but degenerated cartilage will just continue to "grind" the meniscus like sand paper. So, the goal is to reduce degeneration of cartilage. I plan to continue on this formulation for 1 year and see where it takes me. My knee arthritis does not produce chronic pain, though most days low to moderate discomfort. I am 70 yo and exercise consistently including a return to measured weekly running. I am interested in reading your thoughts on this regimen. Thanks for your informative posts .... much appreciated.
@JeffreyPengMD
@JeffreyPengMD Год назад
Thanks for sharing!
@SKs.
@SKs. Год назад
Good video. Extremely informative. Thank you
@faridasukra8570
@faridasukra8570 10 месяцев назад
Thank you so much ❤
@thebrowns5337
@thebrowns5337 6 месяцев назад
Magnesium creams/oils/moisturisers (some with calcium but I'm not sure how well that is absorbed) exist too. BetterYou is one in the UK. May help arthritis in joints?
@helenmontgomery5357
@helenmontgomery5357 Год назад
What about osteoarthritis of shoulders?
@Mickchillagegainford01
@Mickchillagegainford01 5 месяцев назад
I'm 55 and ride BMX bikes on and off for the last forty years. I started with knee pain about three years ago, much physio, insoles for my flat feet and the pain came and went. in October of 2023 the pain retuned and I got an MRI scan in early 2022 , result onset of osteoarthritis, I've been recommended Glucosamine and have been told it could take up 6 to 8 weeks for the pain to go away. I'll try it and see if there is any improvement. If not I'll look to alternatives. Missing my bike riding a lot now.
@porfyformilleza7989
@porfyformilleza7989 6 месяцев назад
Dr. Peng, how do I take this, one capsule daily, with a meal?
@brianbanks3044
@brianbanks3044 6 месяцев назад
i take both Gluc and Chon and Syn Flex for 20 yrs...I stopped the synflex for a month and my knees started hurting...guess what, I went back on synflex and all the pain went away....I will take both for the rest of my life
@mikelanglow-bi2sv
@mikelanglow-bi2sv 9 месяцев назад
THANKYOU. Respect -
@charleshamilton585
@charleshamilton585 11 дней назад
Can people with hypertension and kidney issues take this for joint pain?
@olivemasina3878
@olivemasina3878 2 месяца назад
Does it work for meniscus tear pain and stiffness ?
@thegormlesstwit849
@thegormlesstwit849 Год назад
Thanks so much for all your videos, I am learning a lot. Can you tell us what that sound is that my knees make when I bend them? It is like a crunching/muching? / grinding sound. Do I likely have fragments of bone and cartilage floating around in there? In that case, will PRP help much, or is it too far gone?
@JeffreyPengMD
@JeffreyPengMD Год назад
Best to get evaluated by an orthopedist!
@thegormlesstwit849
@thegormlesstwit849 Год назад
Thanks, Doc. I want to get a scope in there to see what's really going on
@rohanangne6212
@rohanangne6212 Месяц назад
I have fluid collection in LHBT and beneath rotator cuff..also I have bursa..should I take this supplement? Will it help me reduce inflammation and heal tendons? please answer Sir
@swapnilkabra2906
@swapnilkabra2906 5 месяцев назад
Hello sir, My doctor has given me glucosamine only but not chondroitin. Can you suggest medicines containing both the combinations. I am from India and I am taking Lubrijoint od. Thanks & Regards Swapnil kabra
@ditadayos2853
@ditadayos2853 Год назад
Where to buy
@jakobw135
@jakobw135 3 месяца назад
Is OZONE INJECTION a valid treatment for osteoarthritis?
@BradiKal61
@BradiKal61 5 месяцев назад
Started getting knee and joint pain in late 40s (after being put on statins for high cholesterol, and was told by friends that they felt statins were the problem). After stopping the statins mist of the effects seemes to decrease but not disappear. Doctor later recommended glucosamine & C) which Ive been on for almost 5 years and joint pain and weakness feels much better but I can't say my regimen is a guaranteed success. Thanks to Costco prices my G&C costs are low so I keep taking it. The recent discussion about unknown higher levels of microplastics in bottled water may explain a LOT of health issues and I hope THAT research ramps up immediately.
@paulwittmer6838
@paulwittmer6838 5 месяцев назад
Are there any studies that consider topical application of glucosamine with condroitin versus oral?
@azhurelpigeon
@azhurelpigeon Месяц назад
I’m not taking it for arthritis, my knees just hurt because I walk a lot as I have two jobs. What do I take for joint pain from over use, not age or damage?
@bcrigg9388
@bcrigg9388 Год назад
Greetings Dr. Peng. I watched the above video, as well as dozens of your other videos, including the video on Tumeric & Curcumin. Since both videos indicate potential benefits to inflammation & pain reduction, do you recommend taking; Tumeric & Curcumin As well as Glucosamine with Chondroitin?
@JeffreyPengMD
@JeffreyPengMD Год назад
Both seem like low risk high upside and worth a try, especially turmeric/curcumin.
@BombedBadlandBrawl
@BombedBadlandBrawl 7 месяцев назад
I take glucosamine, chondroitin, MSM, hyaluronic acid, boswelia serrata, rosehip extract, curcumin, piperine and Type 1-2-3-5-10 collagen. I have no osteoarthritis or anything but just to keep my fitness intact. The recovery of joints is insane. After every hardcore workout, next day the joints feel like I haven't worked out in ages, I am ready to go another huge session.
@busybeeteach
@busybeeteach 8 месяцев назад
What about effectiveness in spine and hip osteoarthritis
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