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Chromosome and Kinetochore (2014) Drew Berry wehi.tv 

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This visualisation is a multi-scale reconstruction of the organisation and structural features of DNA inside a chromosome of a living cell.
Multiple forms of data are seamlessly woven together to accurately reconstruct the molecular systems that build, organise and coordinate the living library inside our cells.
This visualisation is from two figures that are combined with text, interactive widgets and imagery through the narrative of 'E.O.Wilson's Life on Earth' interactive textbook of biology.

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5 окт 2024

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Комментарии : 216   
@fishflavoredicecream
@fishflavoredicecream 7 лет назад
This is simply one of the best videos on RU-vid. Educational, scary as fuck but funny as hell. The way they animated kinesin and dynein walking along the MT was cute and comical
@did_i_ask_btchDO_i_look_i_care
@did_i_ask_btchDO_i_look_i_care 2 года назад
🙂even I used to get scared in childhood bt now I sleep with skeletons😂
@namthainam
@namthainam 10 лет назад
WOW! WOW! WOW! Thank you for making this in-depth knowledge accessible to someone without a biochem degree!
@FBWUniverseMode
@FBWUniverseMode 3 года назад
This is hard to believe, it's mind blowing that all of this is happening right now and in high speed and THAT ITS ACTUALLY HAPPENING!
@RaviGarlapati
@RaviGarlapati 3 года назад
And that it's happening in each and every tiny part of ourselves..... With no intention or involvement of ours
@kijuubi
@kijuubi 3 года назад
@@RaviGarlapati wtong the frequencies determine it, which are we.
@sea5205
@sea5205 3 года назад
God is good
@يزيدخرمي-ق2ل
@يزيدخرمي-ق2ل 2 года назад
This is the creation of our great creator, he is Allah (God)
@Ranjan_Mohanty
@Ranjan_Mohanty Год назад
@@يزيدخرمي-ق2ل your allah is a bitch who you fuck 5 times a day, now go back to fucking.
@jagathperera5287
@jagathperera5287 6 лет назад
Wow...animations and sound effects are amazing....
@darkstatehk
@darkstatehk 2 года назад
Because of your videos, my son took a keen interest in biology at high school. Thank you for posting such amazing educational works.
@paulferry7791
@paulferry7791 5 месяцев назад
What's amazing isn't how quickly this seemingly takes place but rather at the perspective of molecular motion through the myriad of interactions time transport for us and how slowly. It's not moving fast so much as we are moving so much slower in comparison.
@viperhc
@viperhc 11 лет назад
I also really enjoy these animations, so incredibly fascinating & amazing as to what happens in each of our trillions of cells.
@blueblimp
@blueblimp 5 лет назад
The first part reminds me of Neo waking up from the matrix in The Matrix. Great stuff.
@brianjones483
@brianjones483 11 лет назад
Whenever I watch these videos I'm always amazed by the fact that, if you subscribe to a strictly mechanical view of the universe, this is what you get when hydrogen gas gravitationally collapses. The universe is a complexity engine. Life is a creative dissipation of the big bang's initial energy.
@AuroraEAustralis
@AuroraEAustralis 3 года назад
I love the sound. I love how everything looks robotic Micro world in us
@pilotavery
@pilotavery 3 года назад
Biology is just nano robotics...
@kijuubi
@kijuubi 3 года назад
@@pilotavery how is it only robotic, i think it has a consciousenes. If u think u are just a machine, then u failed to understand your true being outside of this world.
@pilotavery
@pilotavery 3 года назад
@@kijuubi each of these individual proteins are not conscious. They are molecular machines that have a very very precise output. Very consistent as well and the same Gene always encodes for the same protein which always has the same behavior. Someday we are going to figure out how to make a computer conscious, since we already understand how neurons interact with each other, however that doesn't mean that it's not a machine. Each individual piece is still predictable, the consciousness is emergent behavior
@kijuubi
@kijuubi 3 года назад
@@pilotavery be quiet human i cannot stand your bs stuff anymore, beleieve what u want and shatter in your ignorance. you already live ina consciouse computer, to be precise ina a fractal consciouseness but imprisoned in your own fractal hence your replicatable and reverted processes, u wont find nothing out there.
@pilotavery
@pilotavery 3 года назад
@@kijuubi do you understand how protein folding works? Google was able to solve this and it only is solvable because individual proteins behave as molecular machines. We've even synthesized custom proteins that behave exactly as designed. A computer is just a machine but it can perform complex calculations because of the emergency behavior happens when you stick them together in certain patterns. proteins by themselves are not conscious, just like individual brain cells are not conscious.
@leejohnson262
@leejohnson262 6 лет назад
imagine watching this high
@usualdosage7287
@usualdosage7287 4 года назад
It changed my life
@mkultramarine1692
@mkultramarine1692 4 года назад
equally as crazy
@johngraham1407
@johngraham1407 4 года назад
Freaked me out😵😂
@JasonCunliffe
@JasonCunliffe 3 года назад
Just watch it & you will get high !!
@ZodiKeesh
@ZodiKeesh 3 года назад
Me rn and I just 😳🤯
@thomasbeatty9496
@thomasbeatty9496 Год назад
The best example of cell mitosis I have ever seen. Absolutely great for someone interested in Genetics. Thank you.
@Novak2611
@Novak2611 10 лет назад
Mind blowing !!!
@alexacarenati
@alexacarenati 8 лет назад
mindblowing....
@thatnerdguy5541
@thatnerdguy5541 4 года назад
Thanks for this explanation!
@赵雪冰-i8z
@赵雪冰-i8z 10 лет назад
Life is so amazing!
@AB-if8pd
@AB-if8pd Год назад
This is totally awesome and unbelievable. I'm in a state of awe...😮😮😮😮
@robertohvargas
@robertohvargas 2 года назад
Les quedo bien chingon.! Si Watson y Crick presenciaran este video en su epoca, seguro se vienen y se cagan al mismo tiempo 😂. La precision al conservar las proporciones y dimensiones en la animacion 3D, es lo que le da el toque de presenciar algo que ningun humano habia visto antes, y que al mismo tiempo sucede miles de millones de veces cada segundo de nuestras vidas. Este video es un trabajo Magistral sin duda! Felicidades!
@inthefade
@inthefade 11 лет назад
I love these animations
@cjhepburn7406
@cjhepburn7406 4 года назад
Simulations...from what I understand.
@gumnaampkgroup1057
@gumnaampkgroup1057 4 года назад
ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-H7lsvscX7rg.html
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
@@cjhepburn7406 It's only partially simulated, the rest is/has to be animated by the team - because they're trying to show the mechanism of something that, in reality, is naturally stochastic.
@ksurovov
@ksurovov 8 лет назад
2 cancer cells disliked this video
@KaushikBoruah
@KaushikBoruah 7 лет назад
just to let you know the cancer is increasing one cell a year
@oleksiilapenko4968
@oleksiilapenko4968 6 лет назад
we have a small tumor here, it's 12
@chinnuliya
@chinnuliya 5 лет назад
It's 16 Now....
@naimishkeswani7923
@naimishkeswani7923 5 лет назад
Now 18
@hackart8973
@hackart8973 5 лет назад
20 canser
@NeuralAcademy
@NeuralAcademy 5 лет назад
AMAZING VISUALS!!!
@DaLokNessMonster
@DaLokNessMonster 7 лет назад
Really helped my understanding thanks so much!!
@ЄлизаветаХарькова
That’s the scariest educational video I have ever seen
@suraiyaaktermeghla1325
@suraiyaaktermeghla1325 3 года назад
Really Mindblowing😳😱😱
@flygirlzaz
@flygirlzaz 4 года назад
This is an incredible video. Wow.
@sadiasarki2021
@sadiasarki2021 2 года назад
Amazing 🌼
@anamfatema7584
@anamfatema7584 4 года назад
Subhanallah what a creativity and complicated it is Allah subhana wa talla make it mashallah Best vedio and explained excellent awesome bro
@Ranjan_Mohanty
@Ranjan_Mohanty Год назад
allah didn't do shit, now go and fuck allah.
@dylanboye05
@dylanboye05 4 года назад
amazing and trippy video
@gewargisgeorgios8186
@gewargisgeorgios8186 6 лет назад
Fascinating stuff
@peacepeace8164
@peacepeace8164 7 лет назад
Thanks
@Byggarebobo
@Byggarebobo 8 лет назад
Cool video, but keep in mind that this is not how it really looks or works. For instance the force driving the separation of the chromosomes is generated by microtubule and mediated by a ring like structure that wraps around the microtubules, called the dam1 complex, this complex is attached to the huge kinetochore complex. Neither is really visualized here and there is much more structures and machinery that is yet unknown participating in this process.
@quinxx12
@quinxx12 7 лет назад
The ring complex is not the only force. The chromosomes are also pushed from both sides by Kinesine-motors.
@Byggarebobo
@Byggarebobo 7 лет назад
The ring complex is not generating the force, the force is generated by hydrolysis of gtp by beta tubulin and stored as structural strain in the microtubule lattice until microtubule begins to depolymerize. During depolymerization the proto filaments curve outwards which makes the ringstructures slide up along the microtubules. But yeah there are probably motor proteins involved as well
@Thomaaasooo
@Thomaaasooo 7 лет назад
very interesting, but they did not "forget" Dam1 in this animation. Dam1 only exists in fungi and there are no Dam1 homologs in mammals...
@williamwheatley1852
@williamwheatley1852 Год назад
I'm quite glad I saw your message as I was starting to think where the kinectochores had come from, if their waiting for the signal that everything is in the right place and tension is correct then where are they stationed beforehand. You give me reason to believe there's a place for that which may not have been built in this animation.
@DaLokNessMonster
@DaLokNessMonster 7 лет назад
This is so beautiful
@unnitamahato1579
@unnitamahato1579 3 года назад
Structures are very detailed. Very good video.
@alaaalsamany7520
@alaaalsamany7520 5 лет назад
سبحان الله Amazing vidio and clear explaination
@Ranjan_Mohanty
@Ranjan_Mohanty Год назад
Fuck allah!
@larina4211
@larina4211 4 года назад
is the part of the microtubule next to the kinetochore is the + or - extremity
@moonchild4u
@moonchild4u 3 года назад
Best video
@Majintel
@Majintel 3 года назад
are the blue things in 3:37 also kinesins? and what is their role??
@huijieyuan4649
@huijieyuan4649 4 года назад
I love your BGM, it's very interesting!!!
@XxBongZilaxX
@XxBongZilaxX 5 лет назад
So there's something here?
@smitheesaha6678
@smitheesaha6678 4 года назад
are chromosome found in every cell?
@isuckharderthanlife5413
@isuckharderthanlife5413 4 года назад
Only cells that have a nucleus. Red blood cells for example have no nucleus, therefore no chromosomes.
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
It's also important to note that prokaryotes also have chromosomes, just that most of them are circular and are unlike the chromosomes of eukaryotes.
@amritam4737
@amritam4737 2 года назад
Just Thank you 🙂🙂
@bikrammajhi7278
@bikrammajhi7278 3 года назад
Wahhh!!!!OOOh Amazing video. Thank you guys.
@dannyali7305
@dannyali7305 5 лет назад
So what's the smallest thing in brain?
@yeamsalvacion4324
@yeamsalvacion4324 4 года назад
You
@Millmar
@Millmar Год назад
Gorgeous 🧬❤❤❤
@aayushphadte
@aayushphadte 4 года назад
Satisfying video 💚🤤
@orsonkaart1853
@orsonkaart1853 3 года назад
Incredible video's, easy to follow and great to watch !
@Dunya202
@Dunya202 10 лет назад
very helpful. thanks.
@genicadelara5243
@genicadelara5243 4 года назад
This is the best!
@ayeshafazal391
@ayeshafazal391 6 лет назад
Fantabuluous
@Celine76488
@Celine76488 Год назад
Omg this was so informative thank you
@jacobogle8784
@jacobogle8784 10 лет назад
Amazing
@monuvermagymlife8347
@monuvermagymlife8347 2 года назад
Very nice video sir
@clinicalpharmacy3
@clinicalpharmacy3 8 лет назад
plz tell me : is the microtubule binds to the kinetochore it self or to the motor proteins ?
@khadejaalom1954
@khadejaalom1954 4 года назад
I think the microtubule first come to the kinetochores and then both of them work as a magnet
@immrainberry8658
@immrainberry8658 4 года назад
Very helpful, thank u
@tanishqroyal2184
@tanishqroyal2184 3 года назад
Mind blowing concept and animation👌
@simonewalter8020
@simonewalter8020 3 года назад
Great. Thanks a lot 🌷
@lorisperfetto6021
@lorisperfetto6021 2 года назад
I've seen molecules WALK
@joshuamangerel4722
@joshuamangerel4722 7 лет назад
cool video but what's with those weird sound effects lol
@michael18276
@michael18276 6 лет назад
the sound effects are the best part.
@avishaksingha671
@avishaksingha671 5 лет назад
Really helpful thanks..
@subhamkarmakar3320
@subhamkarmakar3320 3 года назад
Next level 🔥🔥
@mariamzayed91
@mariamzayed91 5 лет назад
OMG Awesome vedio!!!! Thank u very much!!!!💙💙💙
@KkT-i3i
@KkT-i3i 4 года назад
Good
@brekhnakhan5183
@brekhnakhan5183 2 года назад
Very nice
@khadejaalom1954
@khadejaalom1954 4 года назад
Well my question is does the kinetochore disattach themselves or the microtubule pull the kinetochore? And does the divided kinetochores have the same amount of molecules at each of them?
@Curtainstag_e
@Curtainstag_e 2 года назад
What is your major? And which year at college?
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
For the first question: the microtubules pull the kinetichores apart. As for the second one: that's a bit of a silly question to ask; it's a bit complicated and oddly specific metric to try to measure/answer, that's like asking how many sleeping blind people are there in a skyscraper.
@ലൊട്ട്ലൊടുക്ക്
Superb ❤️❤️
@aaaaaaaaaaaaaaaaaaa790
@aaaaaaaaaaaaaaaaaaa790 4 года назад
This is terrifying.
@goosecouple
@goosecouple 6 лет назад
Most of this is based on imagination. The electron microscope doesn't have such a strong resolving power.
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
We use x-ray diffraction and NMR to capture the structures of these molecules, not electron microscopes. Electron microscopes only give us the rough/general shape or outline of large macromolecular complexes.
@chrisvinu
@chrisvinu 11 лет назад
congratulation
@charlizecramer117
@charlizecramer117 3 года назад
definitely could've gone without the sound affects.
@zahranouri7577
@zahranouri7577 8 лет назад
very niccccceee
@doodelay
@doodelay 4 года назад
I think I've been dumbfounded
@PacificCircle1
@PacificCircle1 10 лет назад
Good evidence for evolution. Millions of molecules in billions of cells in million of organisms equals many chances for error, i.e., mutations.
@FairyRat
@FairyRat 8 лет назад
It's really amazing what the law of large numbers is capable of given our universe.
@PacificCircle1
@PacificCircle1 8 лет назад
FairyRat Trillions of rolls of the dice will eventually result in many things. Given a nation of millions of people with inventive attitudes, they are likely to invent cars, computers and Moon shoot rockets.
@crisjones7923
@crisjones7923 6 лет назад
I can't tell if you are serious or trolling...
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
@@crisjones7923 wdym?
@sadiasarki2021
@sadiasarki2021 2 года назад
Love it
@wisdom9195
@wisdom9195 3 года назад
Broooo, I'm high as fuck and this just blew my mind.
@shahnawaz007
@shahnawaz007 3 года назад
Iam watching this video I just says OH MY GOD 🙄
@bultaco2222
@bultaco2222 4 года назад
omg brilliant
@higginswallop5009
@higginswallop5009 2 года назад
Is this a prank or is it real?
@alhaeri1
@alhaeri1 3 года назад
great
@afifayousaf2466
@afifayousaf2466 5 лет назад
2:01 diphallia?
@Василий-т2ч8ь
@Василий-т2ч8ь 4 года назад
Все больше склоняюсь к тому,что Вселенная как и Человек- Бесконечны!
@sakubashiba3610
@sakubashiba3610 2 года назад
can we please somehow create an O chromosome ?????? you take the O you split it you get o o then it gets larger to O O.... this X and Y is so inneficient....in theory a O chromosome dna sequeice can be build right? wth dude why is the body so dumb... making x and y when O is 1000% better no end cell death or cell aging.... jeeeeez and i thought the body is smart.... also can someone theoryse what would and O chromosome species be ????
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
Circular chromosomes do exist but they're only found in most bacteria and archaea. Also, the X and Y chromosomes aren't literally referring to their shapes; all chromosomes are sausage shaped, but they come in pairs and are bonded together in the middle, hence the "X" shape.
@toheed_zafar381
@toheed_zafar381 3 года назад
Never saw this tyoe of video
@ranaaydn8989
@ranaaydn8989 3 года назад
that was amazing!!!
@antagonizingusername
@antagonizingusername Год назад
athiests be like "yup, this just built itself in a pool of warm rocks"
@GuardianSoulkeeper
@GuardianSoulkeeper 11 месяцев назад
Nope.
@Gelatinocyte2
@Gelatinocyte2 Месяц назад
No atheist ever actually says or believes that. What a very dumb strawman. Nice try.
@monuvermagymlife8347
@monuvermagymlife8347 2 года назад
Aur banaiye video
@munazzasadaf7132
@munazzasadaf7132 4 года назад
The only 46!!!in one cell
@gopikrishnamanaidu1130
@gopikrishnamanaidu1130 4 года назад
wow wow wow iiittt iiss aawweessoommee super i love but it was like boiling an omelete
@browseforsports7275
@browseforsports7275 6 лет назад
Subhan ALLAH
@Ranjan_Mohanty
@Ranjan_Mohanty Год назад
allah needs a good fuck !
@junaid8707
@junaid8707 4 года назад
Allah has made cells so complex
@Muhammad-Ateeb.S
@Muhammad-Ateeb.S 2 года назад
Insane
@Hyumanity
@Hyumanity 2 года назад
Fucking beautiful!!!
@deadchannel4275
@deadchannel4275 8 лет назад
3:40 walking chemicals
@cjhepburn7406
@cjhepburn7406 4 года назад
I don't know if they're figurative of literal representations. Imagine if that's their actual anatomy. Lol!
@gumnaampkgroup1057
@gumnaampkgroup1057 4 года назад
ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-H7lsvscX7rg.html
@inserthere6387
@inserthere6387 5 лет назад
wow
@red8527
@red8527 4 года назад
What the fuck did I just watch???
@afafmkimel4885
@afafmkimel4885 3 года назад
سبحان الله ❤❤❤❤❤❤❤❤❤❤❤❤❤❤❤
@betteru7676
@betteru7676 2 года назад
This vdo is hilarious...
@mimizdani8194
@mimizdani8194 4 года назад
سبحان الله
@elmoudenabdelmouhsine9035
@elmoudenabdelmouhsine9035 3 года назад
لا اله الا الله العظيم سبحاااانه عما يشركون.
@kaanugurlu5251
@kaanugurlu5251 9 лет назад
jesus fucking christ this is sp00ky
@Yasmeentea
@Yasmeentea 9 лет назад
+kaan uğurlu I know. It was fucking scary in a weird way.
@rajadcruz1919
@rajadcruz1919 7 лет назад
kaan uğurlu mind ur language
@wvhillbilly1909
@wvhillbilly1909 10 лет назад
There's just no way this could happen by chance--it's far too complex. Only God could design something like this.
@blurryimage4585
@blurryimage4585 10 лет назад
Of course it couldn´t happen by chance. That´s why we use evolution to explain it, or God to avoid the explanation.
@faithwhatevers4165
@faithwhatevers4165 9 лет назад
"I don't understand something outside my knowledge base, THEREFORE GOD!" -every idiot ever
@rowanvanderven6967
@rowanvanderven6967 9 лет назад
+lenka z evolution is based on random variation = dumb luck
@blurryimage4585
@blurryimage4585 9 лет назад
Dutch Guitar If it was = it would be. But it´s not. It´s only you exposing ignorance again and again. Boring.
@rowanvanderven6967
@rowanvanderven6967 9 лет назад
random variation and natural selection can not explain the extreme complexity in the cell. Or the fact that we have heart, lungs, nervous system, muscles, organs etc. We have 100.000.000.000.000 cells in our body and we can't even explain 1.
@did_i_ask_btchDO_i_look_i_care
@did_i_ask_btchDO_i_look_i_care 2 года назад
3:48 wtf