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ERGOTHIONEINE: Can This Little-Known Amino Acid Impact Longevity? [2024] 

Lance Hitchings
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Discover the secrets of ergothioneine, the latest "longevity vitamin" hailed for its antioxidant properties and potential to boost longevity.
Learn what it is and how it works in the human body. Explore its benefits and how its impact on longevity.
Don't miss out on this new vitamin discovery and its role in promoting a longer, healthier life.
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Chapters & Timestamps:
Intro: 00:00
What Is "Ergothioneine?": 00:31
How Does Ergothioneine Work: 01:06
How Does Ergothioneine Impact Aging: 03:42
Sources of Ergothioneine: 06:39
Dosages: 09:25
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Studies Referenced In This Video:
Ergothioneine promotes longevity and healthy aging in male
mice:
pubmed.ncbi.nlm.nih.gov/38446...
Ergothioneine and its congeners: anti-ageing
mechanisms and pharmacophore biosynthesis:
pubmed.ncbi.nlm.nih.gov/37561...
The unusual amino acid L-ergothioneine is a physiologic
cytoprotectant:
pubmed.ncbi.nlm.nih.gov/19911...
Ergothioneine, recent developments:
www.ncbi.nlm.nih.gov/pmc/arti...
Distribution and accumulation
of dietary ergothioneine and its
metabolites in mouse tissues:
pubmed.ncbi.nlm.nih.gov/29371...
Ergothioneine is associated with reduced mortality
and decreased risk of cardiovascular disease:
pubmed.ncbi.nlm.nih.gov/31672...
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Social Media:
Facebook: / lancehitchings
Instagram: / lancehitchings
Twitter: / lancehitchings
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AFFILIATE LINKS:
Get a free month of Whoop using this link: join.whoop.com/35071A
Discount code for Renue By Science: LANCE10
Product Links: alivebyscience.com/all-produc...
Discount code for DoNotAge: LANCE
Annual Subscription: donotage.org/subscribe/
Products: donotage.org/products/
Discount Code for Perfect Amino: HITCH10
PerfectAmino Drink Powder link: affiliates.bodyhealth.com/idev...

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4 авг 2024

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Комментарии : 59   
@tyanite1
@tyanite1 2 месяца назад
You're looking great, Lance. What you're doing is working. I'm not far behind in age but far behind in fitness, biohacking and training. You're the example to aspire toward.
@thomasyoung1588
@thomasyoung1588 2 месяца назад
Good channel. Good presentations.
@shravankumardebbad6620
@shravankumardebbad6620 2 месяца назад
Good information Lance. Thank you. Getting on it right away!
@divided_and_conquered1854
@divided_and_conquered1854 2 месяца назад
Hi Lance - new sub here - I just wanted to say that I _massively_ appreciate your approach, your thoroughness, your impeccable attention to detail, and your refusal to 'dumb it down.' Thanks so much for what you do - you inspire me to vastly increase my knowledge. (I've even gone through over 100 3x5 index cards to aid me in learning the relevant jargon/terms.) Thanks for all you do, Lance! Cheers. 👍💪
@LanceHitchings
@LanceHitchings 2 месяца назад
Thanks, I appreciate that. Sometime this year, I'm planning on releasing a new course on the "Science of Longevity." This won't have any strategies or interventions to defeat aging, it'll be more about how the human body works at the cellular level.
@divided_and_conquered1854
@divided_and_conquered1854 2 месяца назад
@@LanceHitchings It's fascinating stuff to be sure. Cheers.
@mrwonderfulone
@mrwonderfulone Месяц назад
Publish your cards, please.
@aa-xn5hc
@aa-xn5hc 2 месяца назад
Great video, thanks
@danno1800
@danno1800 2 месяца назад
Excellent to discuss a very important mushroom.thanks, Lance - much appreciated…
@parisconstantinou8299
@parisconstantinou8299 Месяц назад
thank you very much Sir!!!for the absolutely valuable information!!!keep on the great work!!
@in2caffeine
@in2caffeine 2 месяца назад
Thanks Lance!
@LanceHitchings
@LanceHitchings 2 месяца назад
You bet!
@Mllet3d
@Mllet3d 2 месяца назад
Another reason why Lion's mane mushrooms are essential and the make the most tastiest steaks
@LanceHitchings
@LanceHitchings 2 месяца назад
I take a home-made tincture of Lion's Mane mushrooms for it's cognitive effects.
@deborahfischer5708
@deborahfischer5708 2 месяца назад
Love this
@LanceHitchings
@LanceHitchings 2 месяца назад
Thanks
@drhowardr
@drhowardr 2 месяца назад
Well done. Finally a video with new anti-aging information. I must have missed the 2009 memo as well!
@rolandsimon5771
@rolandsimon5771 Месяц назад
I love all of your videos. Keep up the great work. We should study the lives of Greenland shark and the jellyfish. A Greenland shark is able to live up to 400 or 500 years. Jellyfish can rejuvenates itself.
@davidgifford8112
@davidgifford8112 2 месяца назад
Another excellent presentation. The perennial problem with mouse studies is that any intervention that protects them against oxitive stress invariably increases their lifespan by 30% (give or take). Humans oxitive stress protection is at least 6x better than a mouse, so any intervention that can support an already excellent system, is only going to add a small additional benefit. That said, as a frequent eater of mushrooms, I’m more than happy to add more porcini mushrooms to my diet.
@francoistourigny3006
@francoistourigny3006 2 месяца назад
I am a mushroom hunter, the season will begin here in Canada, in one month, exited to renew every year with my passion, and here another reason for it, can you verified the amount of ergothioneine in porcini, cantherella , trompet , and matsutake, thank you .
@chris-lk4ml
@chris-lk4ml 2 месяца назад
I like your comment because... I like mushrooms. Happy with my diet
@pluto4D
@pluto4D 2 месяца назад
Sirtuins activators can also act as a two edge sword. They can both suppress or promote specific tumours which can lead to certain cancers. There are many scientific and scholarly articles on this. It would be a lot safer and just as effective to use nicotinamide as it also upregulates NAD, but not sirtuins
@LanceHitchings
@LanceHitchings 2 месяца назад
LIke many aspects of aging, a double-edged sword.
@pluto4D
@pluto4D 2 месяца назад
@@LanceHitchings Thanks for replying Lance. As yet i've not seen any serious negative outcome for humans, only in rodent studies..perhaps sometime in the future we will have a better understanding
@chuclkles58
@chuclkles58 2 месяца назад
Doesn't David Sinclair claim that excess Nicotinamide will down regulate Sirtuin production?
@bradojacko8247
@bradojacko8247 Месяц назад
Can supplementation improve symptoms once declines are noticed, or has testing only been done via supplememtation throughout the life of the mice prior to any onset of declines?
@marcdunivan2436
@marcdunivan2436 Месяц назад
Is there a lab test to include in one's annual physical test battery?
@metapatriot
@metapatriot 2 месяца назад
7:21 King oyster mushrooms 3 oz = 400 mg?? ... or more like 4 mg ? of Ergothioneine
@JonathanOvnat
@JonathanOvnat 2 месяца назад
Google says 2.4-4.9 mg
@chuclkles58
@chuclkles58 2 месяца назад
Good to know even the humble white button mushrooms can provide a reasonable amount 😊
@edwardbearjames2916
@edwardbearjames2916 2 месяца назад
Yeah I'm thinking we've made this all way too damn complicated. I'm feeling better than anytime in my life with focusing on protein and fats. I can now slowly start to incorporate things back in. I had antibiotics, this has wrecked my gut microbiome. Meat seems to finally be healing.
@mreudeco
@mreudeco 14 дней назад
Is it a blood thinner?
@marcelbirgelen7558
@marcelbirgelen7558 2 месяца назад
Hello, have a question does kefir contain ergothioneine?
@LanceHitchings
@LanceHitchings 2 месяца назад
Not that I know of.
@LesWies-qq8lc
@LesWies-qq8lc 2 месяца назад
kefir contains L.reuteri, a gut bacteria which produces EgT.
@LesWies-qq8lc
@LesWies-qq8lc 2 месяца назад
Kefir cantains L.reuteri, a gut bacteria which produces EgT in the gut.
@LesWies-qq8lc
@LesWies-qq8lc 2 месяца назад
Kefir contains L.reuteri, a gut bacteria that produces EgT in the gut.
@LesWies-qq8lc
@LesWies-qq8lc 2 месяца назад
No, but it has L.reuteri, which produces EgT in the gut.
@birage9885
@birage9885 Месяц назад
Just eat mushrooms, they are delicious and healthy in many more ways along with ergothioneine.
@sgill4833
@sgill4833 2 месяца назад
What kind of fermented foods? Kim chee?
@LanceHitchings
@LanceHitchings 2 месяца назад
Mostly tempeh and fermented rice. Here's a link to a chart listing ergothioneine amount in various foods: www.researchgate.net/figure/Ergothioneine-content-in-fermented-foods-and-mushrooms_tbl1_366899093
@jerryh2954
@jerryh2954 2 месяца назад
@@LanceHitchings It's good to see Beer is on that list!
@carlloeber
@carlloeber 2 месяца назад
Simple..
@wread1982
@wread1982 7 дней назад
How will the scammer dr. Sinclair make money of mushrooms though? They are all natural 😂
@dzonthego
@dzonthego 2 месяца назад
Can't assume that because a food has a lot of a nutrients, that it's bioavailable. I am now carnivore 8 months and feel 1000% better than eating "all" my vegetables. Just sayin'.😊
@christopherellis2663
@christopherellis2663 2 месяца назад
104 weeks 🥩
@VTVT1306
@VTVT1306 2 месяца назад
Another carnivore bot reacting?
@FirstnameLastname-pe5ib
@FirstnameLastname-pe5ib 2 месяца назад
​@@VTVT1306Something a vegan bot would say.
@VTVT1306
@VTVT1306 2 месяца назад
@@FirstnameLastname-pe5ib 😝
@VTVT1306
@VTVT1306 2 месяца назад
@@FirstnameLastname-pe5ib just an omnivore who’s tired of the carnivore community and their hallelujah stories 😝
@vincentcwli1
@vincentcwli1 2 месяца назад
this is old news 2009.
@LanceHitchings
@LanceHitchings 2 месяца назад
Not all of us got the memo.
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