All things NAD+. We take a deep dive into Nicotinamide Adenine Dinucleotide. With a fresh perspective on raising NAD+ levels.
We start off with examining just exactly what NAD+ is and how in functions in the human body. We look at many of the enzymes that consume NAD+ and how it gets synthesized…and recycled. Then we’ll discuss the impact that low levels of NAD+ can have on aging humans. And finally, we examine several different strategies for optimizing NAD+ levels.
Everything you ever wanted to know about NAD+!
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Chapters & Timestamps:
Intro: 00:00
What Is NAD+: 00:55
How Does NAD+ Impact Aging: 07:51
What Can You Do To Raise NAD+ Levels: 09:01
FREE Training: 12:25
A 4-Pronged Approach To Rainging NAD+ Levels: 13:31
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Studies Referenced In This Video:
Aerobic and resistance exercise training reverses age-dependent decline in NAD+ salvage capacity in human skeletal muscle:
pubmed.ncbi.nlm.nih.gov/31207...
Skeletal muscle NAMPT is induced by exercise in humans:
pubmed.ncbi.nlm.nih.gov/19887...
Resistance training increases muscle NAD+ and NADH concentrations as well as NAMPT protein levels and global sirtuin activity in middle-aged, overweight, untrained individuals:
pubmed.ncbi.nlm.nih.gov/32369...
NAD+ Precursors Nicotinamide Mononucleotide (NMN)
and Nicotinamide Riboside (NR): Potential Dietary Contribution
to Health:
pubmed.ncbi.nlm.nih.gov/37273...
A small molecule inhibitor of
Nicotinamide N-methyltransferase
for the treatment of metabolic
disorders:
pubmed.ncbi.nlm.nih.gov/29483...
Exercise increases the release of NAMPT in extracellular
vesicles and alters NAD+ activity in recipient cells:
pubmed.ncbi.nlm.nih.gov/35661...
Exercise training upregulates
intracellular nicotinamide
phosphoribosyltransferase
expression in humans: a
systematic review with
meta-analysis:
www.ncbi.nlm.nih.gov/pmc/arti...
NAD+ metabolism and its roles in cellular processes during ageing:
pubmed.ncbi.nlm.nih.gov/33353...
A systems-approach to NAD+ restoration:
pubmed.ncbi.nlm.nih.gov/35134...
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11 июл 2024