Glucomannan Did THIS to My Microbiome 

How could I have missed your content for so long? My spouse is a serious scientist who is scathing about most of what passes for science these days & you are the only nutritionist I listen to that he doesn't wag his head at. I can't tell you what an accolade that is, worthy of some kind of medal. 🎖

This is great study/work!! Doing the study on yourself. Putting it all out for us to see. So much time can be saved and new clinical progress adopted. Thanks so much for sharing your own experience and discovery.

Glucomannan mainly increases Bacteroides. There is a brand new study on this published in 2024. Would love to see more content on specific fibres and how they affect the microbiome.

The only conclusion by listening to you and a host of other top gut experts over the last few years and trying to figure out my own severe gut problems is that no one really knows what is going on in the human gut. Similar to u, at certain times in my life, simply just drinking water can cause severe gas and distention which just shows how crazy and chaotic your digestive system can be. Anyways, I'm still struggling with severe issues, from autoimmune problems to gas/diarrhea, to impaired vision that gets worse when my my gut worsens. All the Dr's from eye specialists to rheumatologists, to (obviously) gastroenterologists have no clue what to do and haven't even been able to give me a diagnosis beyond ibs. I appreciate your knowledge and love your content and hopefully I will be able to one day figure things out. Thx

Would love to see a video about how to restore beneficial species and gut health after antibiotics

I'm late to the party, but great video! I've been trying to cook with glucomannan (and psyllium) wherever possible and it certainly seems to help a great deal (supplementation is great but I find when these fibers are _in_ my food they seem to work even better). Anyway, your comments about stress and sleep really resonated with me, and I wanted to share that anecdotally I went from a decades-long baseline of "miserable" with the occasional reprieve due to glucomannan and psyllium to a baseline of "pretty darn good" with sublime results from these same fibers when I started taking bupropion for seasonal affective disorder. You'd know better than I would, but my working hypothesis is that dopamine regulation helps maintain my GI lining function and high quality prebiotics help maintain my microbiome, and that miracles happen when both are simultaneously at their best. I'll look through your other work, but figured you might find the connection interesting.

I recently found your channel and am in love. Another excellent video! Yes! Talk about phyla because everyone craps on firmicutes but that’s one of our biggest butyrate producers! And yes talk about crossfeeding to highlight the point how complex this topic is. So curious, with akkermansia going up, did you notice any weight changes? That finding is fascinating. So this confirms a paper that recently came out (sorry don’t have the reference at the moment) that fiber will have different effects on different people. Maybe that’s why you are seeing some of the surprising findings. But your physical experience is pretty fascinating. If you felt so great, do we really worry about some of the good stuff going down? It’s such an intricate dance. 👏🏻👏🏻👍🏻👍🏻

Love your realistic context and full of life presentation. Come to Grenada for a vacation and free island tour from me.

Fascinating video! Id love to have a basic introduction of the micro biome at different levels and what we know about their benefits and harms. Thanks!

n equals one is better than nothing. So thank you very much for conducting this experiment and your candor in revealing the results.

I'm thinking that the polyphenols in red wine's may have boosted your bifidobacterium. I read a study that stated "Polyphenol supplementation increased health promoting microbiota abundance of bifidobacterium". The study also report that it reduced clostridium. I guess I may have to take a glass of wine on occasion. Note: Pinot noir, cabernet sauvignon, and syrah are dry wines containing the highest levels of polyphenols. Thanks

One more video idea. It turns out lots of common medications such as oral birth control, steroids, NSAIDs, statins, protein pump inhibitors, metformin, and many others mess up our biome. Of course, antibiotics too. I think it would be a very interesting to find out more.

Can you take PHGG and glucomannen at the same time?

I would love to be part of your glucomannon study next year. I have methane SIBO at the moment. (I couldn’t find an email to send this, so I resorted to a comment. :)

Hmm.... Because just as pioneer functional medicine practitioner Richard lord says.. Depending on the food you eat The Variety of different foods you eat.. They are going to make the bacteria in your gut fluctuate. Beans to raw fruits and vegetables For 3-4 days It All is going to make the bacteria in your gut change. I would love to see you do some videos maybe in the future on how raw fruits and vegetables and things like beans change your microbiome. When you repeat this experiment, you should probably eat the same exact foods for breakfast lunch and dinner every single day while you're doing the experiment. You also have to take in the fact that I'm pretty sure I remember that bacteria is by volume so when 1 bacteria goes up Certain other ones have to drop. It would be great if you did videos on the hydrogen producers and on the bacteria that eat the hydrogen. Few doctors call it the hydrogen consumers. P.S. .What does washout mean, And C- B, And two stand DEV P..S. This is probably 1 of the best videos to come out on RU-vid in literally the last year.

Very interesting. Thank you! I would love to see a video about variety of stool bacteria and what we know about them. And also about variety of prebiotic powders and foods rich in prebiotics and what we so far know about them. Also, about Hadza tribe stool bacterial composition. Supposedly they had the best one from all rersearched ones. I wonder, how well do we kknow what is the perfect composition and proportions anyway?

This is awesome! Thank you for this helpful content.

Thank you for this info! Do you think it can reduce hydrogen dominant SIBO? Would you recommend it for clients with SIBO and C. Diff?

Yes please on cross feeding bacteria, and I started to take bacillus subtilis de111 and my stool became normal was constipated. Took it for 3 days so far. Still learning and will watch your other videos.

You mentioned maybe doing a study in 2023 with volunteers. If you need an individual I am ready for the challenge. Thanks

Is this good for mental health

What brand of glucomannan did you use? Did it make you feel full? Did it help you lose weight? I'd love to see more of your videos/ You did an excellent job here. Loots to think about... Why doesn't gastoenterologists do this type of analysis? I was taking a probiotic (Align which has bifidobacterium longum) and it made me so darn constipated, I wonder why?

Hey, I noticed you didn’t mention the dosages in the experimental setup video. How much did you take of everything and how (empty stomach/with meal, morning/night)? Thnx Really love your channel, have been binging it since I found you :)

What are your thoughts on human milk oligosaccharides? I’ve seen the culturelle products and lots of my patients have asked. Doesn’t seem like it would hurt, but not sure it’s worth recommending to increase bifidobacterium.

Still waiting on your next Glucomannan experiment.

Please make a video about cross-feeding! In particular keystone bacterias

Are you gonna do one 2 week session at the end of the experiment where you take all the prebiotics at the same time. That would be pretty cool to see lol

I would love to learn more about cross-feeding! I really enjoy your experiments! Thank you!

Did you take it as capsules or as a powder mixed with water?

Where are the longer repeat experiements for 2023? I’m on the edge of my seat :)

But surely you didn't eat exactly the same thing every day of this experiment 🤔 so who's to say that it was the Glucomanan that made the numbers change? Maybe it was the various foods.

I'd love to learn about the crossfeeding. That sounds interesting.

Thank you for this information. How much glucomannan did you take daily?

If you didnt do this again and still need volunteers id volunteer. Super interesting

Hey, I’ve been researching this too and my only concern is bowel obstruction. Would it be wise to drink at least 32 ounces to ensure that it doesn’t bulk to the point of not being able to pass through the intestine? Thanks.

Which doodahs produce the hydrogens?

What brand did you take please!! TYIA

Excellant presentation, am a volunteer for the next time, if you need me 😊

Love this Can you tell about blautia bacteria i have 66% in my gut

will this help with leaky gut?

Did your great bowel movements on glucomanan go back to your more typical bowel movement after stopping glucomanan. Thanks for the great info! Keep on rockin!

Great video!!! :D

Will you be updating this any time soon? I just started taking it a week ago, but now I’m thinking I should get off it bc I want to increase lactobacillus and bifido not decrease them 🤔

Hi! What brand did you trust to use?

Why did you choose glucomannan particularly? As opposed to inulin (currently using).

I want to know about cross-feeding relationships if and only if there is some pattern to it all. I don't want to get a slice of an endlessly complex ecology but if there are generally patterns especially related to periodic fasting, then I'm in.

Thank you!

Make the vid about the phylum

Suggestable brand?

Is this one low fodmap?

You should have been a math professor, specializing in teaching statistics 👌

Run it I'm down for the education

Yes I want to learn about crossfeeding relationships!

Which stool test was this?

OMG this is boring!

How much did you take per day?

Now THAT is a smart woman. Take TESTS before and AFTER to SEE its working. Rather- you have a majority of ignorance all over. "It doesnt work" "Its not for me" Its real funny you know? People are soooo ignorant that they think they have to FEEL something to know its beneficial. Or they expect magical results in 2 minutes. Or, they don't follow the instructions. Or they ask "is it safe" 😂😂😂😂😂😂 As if they dont use 7263834 things where they NEVER asked that question not once. Just took it blindly. I mean logically they HAD partake in activities that led them to the point to where they want or need to use glucomannan in the first place. Smh. Its funny. It really is. Also. People have weight gain for different reasons. If your not losing weight, there's an issue somewhere else. Anyway. Smart. Very smart. Unequivocal results. A live undisputed test that tells you what is going on where. Not just blindly speaking out of your rear end. Its great