How Changes in Proteins Can Lead to Diseases

University of California Television (UCTV)

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Dr. Songi Han, professor in the Department of Chemistry, Biochemistry and Chemical Engineering at UC Santa Barbara, talks about her research into the function of proteins in the body and how changes like protein Tau tangles can lead to neurological diseases like Alzheimer's. Recorded on 10/14/2021. [4/2022] [Show ID: 37869]
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8 июл 2024

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Комментарии : 47

@Tagmeinllc 2 года назад

Great presentation thank you. The attraction of the different amino acid sequence to each other has various strengths determined by the sequence of such. Do you know of any litterateur on this? Fascinating!!! Thank you for such an awesome lecture.

@tracyheaslip8754 2 года назад

My lung cancer when it started the proteins in my eyes started causing floaters. My Ophthalmologist told me at the time and have very much to do with my lung cancer. I had it removed and the eye floaters stop for almost 2 years. They came back and my cancer is back. Somebody needs to be looking into this stuff. On top of it every time I cancer grew is when I had a vaccination.

@karenf9137 2 года назад

TH, first, good luck. Ill say a prayer for you. Second, bromelain, the OTC enzyme, dissolves floaters. Third, no promises, but look into lumbrokinase... another enzyme. It may have potential for you.

@karenf9137 2 года назад

TH, I forgot. Look into Thomas Seyfried and his research. Bruce Hollis is another great researcher.

@MK-ih6wp 2 года назад

Oh Tracy, I am so sorry... I have heard enough stories like yours to believe there is a connection. We must demand full investigations.

@MK-ih6wp 2 года назад

@@karenf9137 You seem to know more about C than me. What do you think about RSO, IVM?

@karenf9137 2 года назад

Bromelain helps reduce floaters

@martyngittins1274 2 года назад

The DailyMail ,1 year ago, did an article on the use of Isatuximab in combating prostate cancer and the research carried out by ICR which appeared very promising in this context. What is the current situation with regard to use of this drug&/ or similar drugs which target the CD 38 Protein which seems to inhibit Immune system effectiveness?

@patricksmith8631 2 года назад

Very Nice

@danielmccarthyy 2 года назад

Alzheimers is often called Type 3 diabetes, so we should control our carb consumption.

@tnekkc 2 года назад

If you can watch this whole video, you may have Alzheimer's.

@danielmccarthyy 2 года назад

@@tnekkc I can’t remember the remark that I was going to offer in response to your comment, but I feel certain that it was both pertinent and impactful. If you remember what I was going to post, please leave a note next to my bowl of Jello.

@tnekkc 2 года назад

Note to Daniel: Gelatin dessert/Sugar Amount 0.5 cup 18 g

@pamvic 2 года назад

very interesting video

@riogrl324 Год назад

Brilliant

@ResidualSelfImage Год назад

Tau protein entanglement with beta-amyloid proteins aggregation is a biomarker for Alzheimer's Disease but not a reliable symptoms of the onset of the symptoms of Alzheimer's Disease ...this talk is surveying the current methodology being used to study the pathogenesis of AD and the biochemical and molecular process of AD

@engineersteveo9886 2 года назад

What is the similarity to Huntingon’s ?

@francescomariaraimondo3395 2 года назад

To keep it simple: like many tauopathies, HD is a neurodegenerative disorder which affects both motor and psychiatric function. It's not, though, a tauopathy. It doesn't originate from the aggregation of tau protein fibrils. The hallmark of HD is the amplification of the end region codon CAG which codifies for glutamine (when you have more then 36 repetitions of it, it's said that the protein has a PolyQ tail, since it has more glutamines the usual) of the protein Huntingtin. It is an autosomal dominant mutations, meaning that it is sufficient for you to have one mutated allele of the gene codifying for Huntingtin to be affected. However when the repetitions are between 36 and 40 the disease has incomplete penetrance: meaning, it does not manifest in all patients or is not nearly as severe. It has been shown that Huntingtin (or portions of it) when mutated can form fibril concretions. Though, the many forms of these fibrils and their significance are yet to be fully understood. And it is speculated that some of those could even have a protective value.

@tnekkc 2 года назад

THis is hard for a layperson to understand.

@hairrum 2 года назад

Human body is so complicated!!!!

@MK-ih6wp 2 года назад

Sure makes you wonder if we were made by a higher power.

@hairrum 2 года назад

@@MK-ih6wp FOR SURE!!

@janeteddddd 2 года назад

Its delicate and finely tuned until man made chemicals ruined it. B.i.gharma is determined to disable it and destroy it. No in.jec.tions. no poison pharmaceuticals. Leave the body alone.

@cesargomez6504 2 года назад

180 ° Turn! SEEK YE the LORD while He may be found, call ye upon Him while He is near: [Isaiah 55:1-6-13] BEHOLD, A bright cloud overshadowed them: and behold a voice out of the cloud, which said, This is my beloved Son, in whom I am well pleased; hear ye Him. [Mt. 17:1-5-27] FROM THAT time Jesus began to preach, and to say, Repent: for the kingdom of heaven is at hand. [Mt. 4:1-17-23-24-25] I TELL you, Nay: but, except ye repent, ye shall all likewise perish. [Luke 13:1-3-5-35] THE LORD is not slack concerning His promise, as some men count slackness; but is longsuffering to us-ward, not willing that any should perish, but that all should come to repentance. [2 Peter 3:1-9-18 KJV] 180 ° Turn!!

@MarkThomas123 2 года назад

How could you talk about Proteins and not mention the Spike Protein in April of 2022.. Don't need to know anything else about the video..

@GloryBlazer 2 года назад

Why am I watching this ?

@anneblackmon5846 2 года назад

To exercise your brain to help in avoiding Alzheimers as is shown by … I forgot his name? Or you could study a new language such as Hebrew, or to learn more about Biochem in order to select the best new health food products for your body and brain.

@claudiaeliss 2 года назад

Why are you guys still torturing animals?? Animal experiments are sadistic. What’s the justification to do that in this day and age 🤬

@HM-wz3rl 2 года назад

everything for tech progress 🙌 💪

@patricianoll1229 2 года назад

U can offer yourself for the test

@claudiaeliss 2 года назад

@@patricianoll1229 If you knew anything about the current state of the world you would know we are being tested up and down all day long. Either you are naive or you are somehow profiting from it to think this sadistic, absurd, brutal system has any benefit to anyone