Is Poison Immunity Possible? (Because Science w/ Kyle Hill) 

I'm highly resistant against most poisonous substances, it's also really hard for me to get drunk and pain killers at the dentists don't actually work on me... I would trade my natural resistance to not feel pain at the dentist in a heartbeat

Holy shit, tattoos with Snake venom? Snake handlers are hardcore.

i keep waiting for Kyle to shout "To me Mjolnir!!" or "Odin's Beard!"

I would like him to explain Rasputin, he said you can only build up a resistance to something, but Rasputin definitely pushed that to the point where it seems he was immune to cyanide.

There is a man (who is on RU-vid somewhere, I saw him on Outrageous Acts of Science once as well) who over a period of time poisoned himself with black mamba venom. He then let one bite his arm and hang on for a about a minute. He had so much resistance that he didn't even get weak, just put the snake back and went about his day.

You should do the science of Hollywood inaccuracies for jumping off bridges, out of helicopters high up and other high places no injuries or death.

Also don't attack Russia in the winter

"don't go fighting a land war in Asia" unless you are, wait for it, The Mongol's *Mongoltage*

"Don't go fighting a land war in Asia".... unless your father's name is Philip. If that's the case, ignore the saying and just go nuts. They'll name cities after you.

I once had a food allergy to peanuts and apricots. When I was 9 years old I thought about how the flu shot worked and decided to take small quantities of roasted nuts and dried apricots. I got really sick the first 20-30 times doing it but in less than a year I started getting less and less sick from them. Now I can eat all the nuts and apricots I want. Sometimes you have to adapt instead of avoid. (When I said small quantities, I meant really small at first. Just the oils for the first few weeks.)

Somewhat related: DC's Poison Ivy -- in many continuities -- has an immunity to plant-based toxins *and* has blood filled with said toxins, to the point where her kiss or touch is almost instantly lethal. Starting with _Batman: The Animated Series_, she conferred that immunity to Harley Quinn. (In B:TAS they were hiding in a toxic waste dump; in the comics it's so Harley doesn't die when they ... "play".) Is it even remotely possible to have such a broad immunity (or resistance) to poisons, to the point where one is a kind of multispectrum Typhoid Mary? Or to confer said immunity? Remember, it's ALL plant-based toxins, a fairly diverse group, including some kind of fast-acting mold spores as seen in the recent _Cycle of Life and Death_ series and earlier. (Presumably it would also include the emulsin in bitter almonds that creates cyanide.) More recent versions of Ivy make her part plant, so her biology is already comic book rubber science. Let's also not forget her psychic rapport with plants, or her ability to make them move without anything approximating muscle fibers, or her ability to make plant matter grow even without root systems or nutrients much as the Hulk spontaneously gains mass. Or, for that matter, her "pheromone control" that amounts to mind control.

There is a drink in Japan called Habusake. It's basically a whole rattlesnake sitting in alcohol. The poison is leached into the drink. It is very strong and some people have done strange things when they blacked-out after drinking too much..

Yep Mithridates was famous for poisoning his enemies and feared being poisoned so much he tried to come up with a specific concoction that would grant him immunity to all known poisons.

antibodies are really finicky when it comes to poisons they work but some of time cause side effects such as allergic reactions and very rarely ever cause yourself to get poisoned from the very antibodies it created. the body usually works for the time it is needed without planing ahead.

Um...Mithridates was King of Pontus...Which is in modern day Turkey, not Syria. The Seleucids, what little was left of them, ruled Syria at the time.

As a snake nerd I love how you handled this one!

What I would have loved to hear about in this video is to what degree (s) have the extreme ends of modern research uncovered that it will or will not have desired effects of being immune enough to be considered immune by what standards.

Hahaha, "daddy like." Well the idea of building up a poison immunity has put me right in a festive mood, so happy holidays, Mr. Hill, because Christmas!

What about President Snow, in the hunger games books. He poisoned his meals and then afterward gave himself the antidote after. What would be the effects of this on and in your body?

everything is poison if you take it to much, right? :)

your Inigo Montoya sounds more like Zoolander.

I always thought that line about him "building an immunity" was just another way of saying "I didn't die because plotline". I did not expect it to actually be somewhat possible. The more you know.

My Grandfather used to take arsenic in the spring every year. He would put a drop on his finger and every few days he would add another drop to a different finger, until he was putting a drop on each finger. He did because he mixed his own pesticide which had arsenic in it, so when the wind would blow some of it on him while spraying it wouldn't bother him.

I think this may only work if the poison is something where the smallest dose does not kill or damage you significantly OR is something your body can identify quickly enough (or even at all). There is a podcast called Poisoncast, they go into detail about a number of poisons. My candidate is ricin, not because of Breaking Bad as I have never watched it, but it is just so interesting to me, its mechanism of action.

Is the Secret Santa guy also the Notice Me Senpai guy?

Yes, brush that Thor hair.

Great episode. The timing and sheer amount of great princess bride quotes was...Inconceivable!

Love the references! It makes the video just THAT better!

We're glad you feel better Kyle!

I learn more from this guy than from school......

The Princess Bride is such a classic, watched it on a movie channel last night even though I own it on bluray lol

There's also a group of mystic healers somewhere in Africa or India or someplace that can eat pure mercury and not be poisoned. Eating mercury is like the final test for them, and they say it's sweet.

The Princess Bride was the first thing that came into my mind when I saw the title, nerdgasm!

is this concept similar to the flu shot? in which the the flu shot has some of the the flu virus in it to build tolerance. happy holidays!

You're now my favorite channel. Used all my fave quotes

He should have mentioned Rasputin, who ate a ton of stuff that had cyanide in them and wasn’t affected. He died a bit later to gunshots and hypothermia.

You should do a video about how Poison Ivy can control plants and produce plant venom.She also has an immunity to toxins, as seen in Batman: The Animated Series. Also, can someone really have clorophyll for blood? Might be pretty interesting to talk about.

You are awesome. Merry Christmas

I love the little bounce at 0:19.

Theoretically, how would the floating/hovering/flying Droids in the Star Wars universe work? How would the fly? Droids like the IT-O Interrogator, DRK-1 Dark Eye Probe , Prowler 1000, Viper Probe, Marksman-H Combat Remote, G0-T0 and so on.

I'm immune to being a loser

1:56 Snake venom isn't a poison, it's a venom. The difference is that poison is toxic if ingested, while venom needs to be injected to be toxic.

This has become my favorite video just for the massive references to The Princess Bride, my favorite movie.

"Because their already poisoned. Ye?- Yeahhhh"

Snake venom isn’t a poison. It’s a venom. Duh.

Kyle's hair is BOSS.

I always wondered about this! Thank you!

I thought that this would be a neat skill but then I realised that it is batshit crazy

Inconceivable!

It's absolutely possible. Just be a Steel-type. Checkmate.

Mithradatius story sounds like a lot of that of king Bindusara Indian king whose teacher poisoned him bit by bit till he became resistant to Poisons.

There are people on medications whose doses rise dramatically to a point where if a person is not likewise attuned would die attempting the same level of medication. So tolerance, or lack of, would simulate immunity or susceptibility in this case.

Hello. My name is Inigo Montoya. you killed my father. prepare to die. wait was that the demoman's beer?

Do a video about One Punch Man's power! :D

There is also another explanation as to how Wesley poisoned Vizzini (Vissini?) without being poisoned himself. As we see in that whole sequence Wesley is actually an unreliable narrator (we cannot trust that he is telling the truth) so it is possible that he lied to Buttercup about how he survived and poisoned Vizzini. First off, let’s think about one important thing: how we smell. We smell things by having particles enter our nose and inside there, can attach themselves to receptors based on the shape of the molecule (So yes, when you smell crap, you are indeed inhaling crap). If Iocane Powder is scentless then it does not correspond to one of those receptors, and so, how would you know if you inhaled it? This is important because the inside of your nose is very porous and the blood stream is very close to the surface (this is why people snort things, it gets it into the blood stream faster). When Wesley asks Vizzini to smell the powder, it very well could have entered Vizzini’s nasal passage and once it was in his bloodstream, poison him. If we assume this, the rest of the sequence is Wesley stalling for time for the poison to work and the cups were never poisoned at all. This could also help explain Vizzini’s erratic and rambling behavior around the scene of drinking from the cup of wine and shortly before, his brain was already shutting down (due to the suddenness of the death and loss of motor control, I’m going to assume the poison attacks the nervous system of the victim). Conceivable?

It's interesting going through these videos and seeing his different hair length

You said, "Anybody want a peanut." You are my favorite now!

Now I want a beer... awesome stuff as always, Kyle Hill

I was hoping for a " SUPRISE COBRA" but this was a good video none the less.

"i don't think it means what you think it means" very subtle

LOVED the Princess Bride theme!

I totally want to try the snake venom thing

INCONCEIVABLE............... diggin your shows kyle. keep up the good work

okay, so I know I'm super late with my comments, but I was just thinking about how zero point energy works. Could you explain this concept, and possibly work in how it could effect the abilities of thor's hammer and/or the abilities of the juggernaut?

Is that the guy from those crazy tv news interviews? Looool

this guy had someone write in princess bride material. No way he knew it by heart.

I'm an example, I was born and created aside of a petrochemical pole, and one day we had to paint the house with diluted ink for wood, in a few hours with mask my mom started to feel bad for ink intoxication but she is ok, but it took me 3 das without mask to start feeling something, and not as bad as my mom

Can you please make a video about the scene in "THank you for Smoking" where the doctor tells the main character he can never smoke again because of a nicotine overdosage? I would love to know the science behind that. Although it's mostly biology, and I've seen you do more physics stuff, this episode seems to show that you are doing biology aswell...!

Just watched this movie the other day. Such a classic!

Riddick used this trick in the latest of his adventures to escape from a mud-crawling beast thing. I think.

Heard about a guy who had more than one liver(can't remember how many) which made it hard if not possible to get drunk.

Just saw this scene again last night! Come tihs morning, this video! Ha! great timing! :) This was the best movie ever btw

"Because, science", what a great verb.

I just rewatched Ninja Scroll like 2 days ago too, how timely.

Loving Kyles chrome comb.

I was combing my hair when that secret santa scene happened.

Why is it when Transformers convert from robot mode to alternate mode, their alternate modes are clean or in other words in complete sheets of metal unlike the toys which show the parts that need to Transform. Basically, how do the Transforming parts recombine with each other every time and there are no spaces present between them when in vehicle mode (like the toys)

I have a mild immunity to certain snake venoms for instance brown snake venom is non lethal to me and all it dose is make me shake and give me a high and a sharp pain in my head. I found out a few years ago.

As soon as i saw the title about poison immunity i knew immediately there would be Princess Bride references

The count of Monte Cristo does the same thing. He took increasing dose of poison to build a tolerance Dumas forever:D

The fact that the poison was used in Italy even fits in the movie's canon because Sicily in in Italy

All the Princess Bride puns!

I've heard that the Honey Badger can sleep off vemon that it has recieve from bites from Black Mambas among other vipers.

so theoretically; you walk into a old west bar the man behind the counter pulls out a shot glass, fills it with whiskey, grabs a snake from under the counter, and expertly squirts its venom from its fang directly into the shot glass. would *you* take the shot?

so if it impairs the bowels ability to absorb more poison is that good or bad? how does that affect it ability to absorb other things like nutriants

reminds me of those mouses in Australia (because of course) who are in a constant battle against a group of snakes. the mouses are becoming more and more resistant to the poison of the snakes, so the snakes poison becomes stronger and stronger. these two are now one of the most poisonous snakes and most poison resistant mouse in the world. these snakes could kill almost every living with easy, except those mouse. sorry if i used the word mouse wrong. not native English, dutch and dyslectic.

Okay, what is the upper limit of arsenic resistance one can reach given infinitely long time? 2g? 5kg? Specifics pls

Prince humperdink was smelling the iocaine and then he was like "iocaine, I'd bet my life on it" but it's funny because Wesley said it's odorless... XD

in show he said poison from Australian tribe...so probly a ground up mixture roots n such powdered

Say "As you wish" with that eyebrow wiggle again...

I'm probably gonna try to build up an immunity to poison too eventually

Hello I`ve got 2 questions. Is it possible to travel trhough time like it was done by Flash? Second question. Does Superman have to eat if he can absorb energy from the sun light?

the ending killed me xD

When I saw the title I instantly thought of the zoologists who make themselves immune to snake venom.

I love the princess bride. Thanks.

a friend of mine has actually gotten bit by a swedish hughorm(dont know the english word for it) three times and he didnt even feel anything so i think he probably somehow is really immune to some poisons

+Nerdist To Kyle Hill; Can you do a video this upcoming Thursday telling how The Flash and his family, (for example Impulse) can vibrate through things, like walls, THANKS!

Thank you for doing s video on my favorite movie of all time ^^

I just want to share the information that my father almost died from poison ivy down his throat as a kid (note it wasn’t the initial plant oil that made it spread into his mouth and throat, it was the oils created from the poison ivy infection itself. Which is not contagious to others because it’s made from your system and blood)

What about Kyle Hill's hotness? Can I build up an immunity to that? So far repeated exposure isn't working.