Mitochondrial Energetics and Insulin Resistance of Aging

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Mitochondrial Energetics and Insulin Resistance in Aging
January 29, 2019
Presented by Bret H. Goodpaster, PhD, Senior Investigator & Director, Exercise Metabolism Core Translational Research Institute for Metabolism & Diabetes Florida Hospital, Orlando
The Lefeber Winter Series on Aging, now in its 24th year, features nationally recognized gerontology research educators, basic scientists, clinicians, and social scientists. Each speaker presents a lecture on an important aspect of aging research and consults with students, faculty, and staff on research topics, grant applications and articles being written for publication.

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8 июл 2024

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Комментарии : 26

@martinirving3824 3 года назад

Interesting, Goodpaster comes to the same conclusion as Frank Shallenberger did a long time ago. The real factor is the loss of fatty acid metabolism and increasing reliance on glucose (which requires less oxygen to convert that fuel to ATP) as the hallmark of aging, and accelerated aging in younger subjects. To be a fat burning machine you need mitochondria that happily burn fat in high oxygen states. That probably means eating less glucose-promoting foods and more healthy fats along the way.

@rliao 2 года назад

The older, shriveled-up mitochondria illustration cracks me up

@thehealthychefri 3 года назад

Lift weights, the more muscle you have the more insulin sensitive and fat adapted you will be!

@jondavidg3155 3 года назад

did he just show scientific proof that thick thighs save lives?

@petercyr3508 3 года назад

I would bet 90% plus of people newly diagnosed with type 2 diabetes have tons of insulin in circulation if the doctors would just measure it. BG goes out of control when the insulin resistant liver produces and releases way too much glucose and then the patient piles on with all the crap they eat. Since 2018 the ADA guidelines have a lukewarm but actionable acknowledgement that a low carb diet is treatment for T2D as part of a patient centered approach. I have been successfully controlling my BG since 1998 this way since diagnosed at age 40.

@charlespackwood 2 года назад

Amazing information. EVERYBODY needs to know this! Thank you, for putting this on RU-vid.

@250txc Год назад

Mr Goodpaster lays his findings pretty well I'd say .. ESP the part on 'just do something' as your exercise routine ... Do whatever to accelerate your heart rate and stay with it over yrs ...It really is this simple for most of us ...

@OGMann 2 года назад

I lived on Galveston in the early 90s. My family had a restaurant in a hotel next to Sealy/UTMB. We had a lot of the burn victims and their families stop in.

@wmp3346 2 года назад

Get up and move people, how is older defined? Last slide was very blurry, but I liked the concept

@health-seeking 2 года назад

Great research . Thank you!

@elenabenjamin9980 2 года назад

Thank you for such as amazing work!

@lauracerva9716 Год назад

This was awesome. Thank yoi

@netto682 3 года назад

👏👏👏🇧🇷muito bom trabalho

@jamesgordon8867 Год назад

I hope you look into photobiomodulation and mitochondrial health.

@Ron-rk6iz Год назад

I think the entire uncertainty about health studies, lies in the fact that we do not understand our Microbiome completely due to its complexity. One person is fat and eats the same as a slim person, the answer is to be found in the Microbiome...