MTHFR gene and supplementation with 5-L-methylfolate | Tim Ferriss 

FMF Clips: Thank you for providing the full vidEO 👏🏻

That’s amazing man! I’m awaiting my Genetic results as I have also suffered from depression, anxiety and crippling fatigue and brain fog for man years. Hoping it provides some helpful information. How are you tracking these days?

@@BFS8811 I live in Canada and it's very difficult to get a family Dr, let alone one who can understand chronic conditions as well as understanding genetics or issues with minerals and vitamins. I paid out of pocket for blood work for 15 months and set up a spread sheet for all of my low levels, or high levels., started tracking my levels and then started attending to each one. High Iron: phlebotomies, Low B-12 started injections, low Testosterone ...Trt creams. I figured it was impossible to have 4-6 rare diseases...so started looking into 1-2 things that could cause all of these things. It's my bodies inability to Methylate....1 thing. It's a fast change at first, then a slow rebuild to undo the damage from years of a completely disregulated system. I am able to exercise daily, I still have zero anxiety and am hoping go off of a sari medication in the next few months as I don't think it was ever helping....slow detox.... I am Not a Dr, an ex teacher and producer who just decided that it was up to me to find answers.

I’m very happy for you! How much do you take? My son is 5 and has the homozygous gene.

may I ask what exact blood tests you ordered please? My wife suffers from 25 years of bipolar depression. All the SSRI's are making her brain fuzzy, bladder issues, anxiety through the roof. I am deep diving into methylation and ordered the mthfr gene test.

@@navyretired230 Hello Sir, I have multiple mutations, homogenized, I am 98% Eastern Europe decent, Germans from Russia. I ordered blood work monthly and charted it so I could follow changes or declines. I asked for all.thyroid tests, male and female hormone levels, b12, vitamin d, liver function, regular blood panel, and Ferritin as my liver had started to crash. I also paid for mineral testing. I now eat a high fat (mostly grass fed beef) high greens diet with very low sugar and NO fortified/ enriched flours or grains..even rice. I stay clear of Folate (it's un unmethylated) which is in sooo many processed foods that I pretty much stopped eating them. All bread and pasta in Canada/USA is a no go, even if it says organic...it then gets "enriched". It's been 4 weeks since going strict and I have not had 1 bout of anxiety, even after having severe ptsd in the past, my brain fog has cleared, adhd symptoms have cleared. I went off of an snri medication and discovered it was not helping at all, also onto consistent morning exercise, testosterone replacement and lots of time in the forest on hikes. I know it sounds crazy, I lost about 7 years of my life, my business, my marriage and nearly my own life to this. I will be grateful everyday now!

What a gem of a post, thank you so much for sharing!

Do it ! I've ordered some anxiety, mcas and adhd have plagued my life for years . Praying they work 🙏

any update? i suffer the same symptoms that you do. not sure if supplementing is worth the cost

@@UUser1337 I started taking methylated folate for a couple months now. It was cheap like $15 for 60-day supply. My energy and mood seem a tad more stable than usual. It's hard to say if the supplement is the culprit, but I will continue to take it.

​@@jzen1455 how much you taking? Might need to increase the dose. Docs prescribe 5mg - 15mg

@@digitalsamurai42 I take 1.7 mg a day.

We are so glad that you've benefitted from the info!

Have you tried 1 avoiding gluten and other plant elections? 2 adding bile salts like "tudca" to your diet? I have found these two steps particularly helpful in reversing what I thought was rapid onset of rheumatoid arthritis. I am slowly getting more flexible and relaxed in my body.

@@brookesenfrance3852what’s TUDCA got to do with mthfr?

Isn’t 7.5mg too low? I see 300mcg being recommended by brands.

@@King311___ 300mcg is 0.3mg brother . Very low

Any advice or source I can use for my son (he’s 5) has the mutuation is homozygous so he must be methfolating poorly. I was thinking around 5-6 mg. Not too much info on the web it seems.

take Sam-e@@lindseyenglehart8670

@@lindseyenglehart8670 hi I would recommend looking into your child's diet first as sometimes some foods could trigger these things.. as diet gets overlooked allot. However if you feel the diet is fine, and you've confirmed he or she has the gene, then I'd recommend speaking to a doctor to find out what dose would be optimal. As your child is very young 5-6mg does sound quite high. Always best to start off with a small dose then see how they respond to it bit by bit. If you do decide to give the Methylfolate, don't forget TMG and vitamin B12 as these keep things balanced. Remember though, the child is young so high doses are most likely not needed. Good luck 😇

How to buy their services?

@@King311___ go to their website and look up their list of practitioners.

Niacine or Niacinamide. Dr berg has a video on it.

how do I find out which one I am on my own?

@@dedmu5793how?

Im going to do it anyway

@@0n344 I already did it. Nothing bad happened. No synergy either.

Folic acid is the synthetic version of Folate. It's in EVERYTHING and as someone with MTHFR I avoid it at all costs. It's taken me a while to realize how sick it makes me. Our bodies can not break it down, it's too unnatural, and if you have MTHFR it just builds up in your system, it's dangerous for people with MTHFR, especially if you're pregnant or trying to get pregnant. Take the natural form (folate), avoid Folic acid.

Yup the person who commented is correct. Take the supplement not folic acid and make sure to eat real foods do not replace it with vitamins

The CDC ain't gospel

They're wrong. Folate is always the superior form.

The cdc don’t care and are outdated

I think it’s just his awkward non-commital drinking behavior, for me at least

He’s so rude when she’s talking he’s pouring his drink and not looking at her meanwhile she gives him her undivided attention when HE is talking

As if he has to be perfect?

Anyone who wants to make a piont of sitting crossed legged like that has to be a complete douche

@@giuseppinasanger6410 He's most likely on the spectrum. The tea is probably a stimulation/focus aid - dopamine related. Also, the gene mutation discussed happens to be comorbid with autism.