Nonalcoholic fatty liver disease is characterized by excessive liver fat in absence of significant alcohol consumption and any other chronic liver diseases. The word fatty and nonalcoholic in this NAFLD are considered as stigmatizing. The word "nonalcoholic" is not capturing the exact underlying cause, i.e. insulin resistance and metabolic dysfunction, of NAFLD. Hence, the experts from global societies, including AASLD, EASL, APASL and others came together, creating a steering committee and a panel of experts, inclusive of hepatology, GI, endocrinology, etc to undertake a consensus document through Delphi method. As a end result of this consensus, MASLD (metabolic dysfunction associated steatotic liver disease) is chosen to replace word NAFLD. MASLD is defined as people with hepatic steatosis and presence of at least 1 out of 5 cardiometabolic risk factors in absence of excessive alcohol intake. A new category, called MetALD, has been created which includes the patients having MASLD along with history of excessive alcohol intake.
6 сен 2024
