Ozempic and Mounjaro causing Muscle Loss ??? 

I took Mounjaro starting Oct 29 weekly until mid January and started alternating weeks until stopping Mounjaro completely April 14th. I did resistance training (LIIFT4 & LIIFT More), walked 1.8-3.35 miles most days, kept protein at 110-135 grams grams.m. I did much of this to prevent lean mass loss and since the start I have lost 84 pounds. The changes in habits I made continue as over the past month I have lost 13.6 without Mounjaro. These shots can be great to break habits, but don’t waste the time you have it, use it as a help for you to change your habits and wean off for a lifelong healthy you.

I’ve been doing Mounjaro 5mg for a month and a half. I started lifting weights 3 weeks before starting Mounjaro. I’m gaining muscle and have also started walking 3 miles at least 3 days a week. I’ve lost 35 lbs since I started the shot and I’m not losing muscle.

So happy. I am entering week 24 and the results have been amazing. On 5mg of Mounjaro and there are doctors out there saying the muscle loss is deadly.

Yeah. Not true. I do resistance training and make sure I get enough protein and I'm gaining muscle and losing fat.

Eat protein and lift weights. Muscle loss will be minimal.

Best looking doctor ever.

Great video, lots of inaccuracies on the internet.

Mitochondria power house 👍..always good information Dr Mike

My doctor prescribed me Mounjaro for weight loss back in July of last year before it became this popular for what it is. I’d never taken anything for weight loss before so when my weight got bad enough that my dr recommended it I made sure to fix my eating and kept working out. Granted I did notice I was able to bench less when I started losing weight but i eventually got back to benching what I used to all while still losing. In total I lost 60lbs and I’m finally able to see definition in my arms and chest. My only recommendation is to drink a lot of water and make sure you keep up with protein intake that definitely helped me. I’m currently on my last injection and I’m a bit nervous because everything I hear about Mounjaro is that as soon as you stop it you gain the weight back but I’m hoping that the habits I’ve been able to gain while on it help me maintain.

Not true! Just got my six month dexa scan and I actually gained muscle!

Most people don’t trqck macros so they are likely to be screwing it up or eating way too little

Good info. Thanks. I was worried about losing muscle mass. I am already doing the 3 recommendations you mentioned. So I hope I will be ok.

Thank you for sharing!Have an awesome day❤You will probably surrounding by patients-Stay well always!!

it's not hard to lose more fat than muscle when you're losing weight (note, I'm not saying that unassisted weight loss itself isn't hard). the problem is, if you don't keep that fat off, then you've done yourself a disservice, because now you've regained the fat and have proportionally less lean mass than you had to start with.

I have been on ozempic since 5/16/23. I saw about 5-6lbs of lean muscle mass, but ive lost 18lbs of body fat loss by october 2023.

11 pounds of lean body mass lost! You say that like that’s freaking nothing. The only people that you are convincing that this is “nothing are people that don’t monitor their body fat and lean muscle mass and realize how much muscle that would be to lose.

Doctor/Body builder. wow.

100% Spot on, 180 # loser here. Gotta preserve at least, or build muscle during meaningful weight loss . 👍

Hi! Do you have any paper that shows the eficience of the resistent trainning on increase lean mass in people who is using ozempic? Tks

Can you speak to how GLP1 medication work on the cellular level beyond slowing your gut, making you feel full…how do they work specifically on a cellular level? I hear bits and snippets on hormones, pancreas, etc., but nothing that pulls it all together.

In 2016 I lost over 100 lbs getting down to 188 doing a whole foods ketogenic diet with intermittent fasting. I kept it off for years but made the mistake of going back to eating sugar again and regained 2/3 of it. This time, I did all the same things but also took semaglutide for 4 and 1/2 months. When I got down to the same 188 lbs losing 65 lbs I was at 21% body fat instead of the 19 I had been at previously at that same weight so I definitely lost a disproportionate amount of lean mass to body fat this time. Also, I can physically see a difference in the mirror at this weight versus doing it without the semaglutide. I physically looked leaner at this way doing it without the semaglutide. That being said, it was definitely much easier to stick to the plan that I made for myself using it so I don't regret it. It is now time to hit the gym and start lifting weights.

Problem is regaining 11 pounds of muscle mass is infinitely harder than regaining 33 pounds of fat

Very helpful information. Thank you, Dr. I read Mounjaro uses artificial hormones. How safe do you surmise Mounjaro is? I worry about cancer since artificial hormones cause breast cancer.

It's crucial that patients get a body composition scan BEFORE they go on these drugs. Then they can see how much LMM they lose and where they lose it. One study found that the loss of LMM was almost as much as the loss of fat.

The thumbnail pic for this vid....😆😘

Just got my 2 week results . Down 10 pounds 8 muscle 2 fat Diet mostly protein some carbs Exercise CrossFit 4 hours per week /4 days 2 hour each Walk additional 8 miles 230 trying to get down to 210 18% body fat

I’m a guy who lifts 6 days a week for years. I had a knee surgery, then had 2 hamstring strains where my cardio and lower body work is very limited. I’m at about 13% body fat and I just need something to push me over the finish line a few body fat percentage points. Being that I have good exercise habits and a great diet for retaining a muscular build, would tirzepatide help or does it only help super obese people?

The problem is those being prescribed this have an absolutely terrible understanding of dieting and what it takes to build and preserve muscle mass. If these prescriptions were used in conjunction with a Protein Sparing Modified Fast there is no way they would have lost that muscle mass

Can you skip weeks? For instance… can you not take it during a hectic month? Or do you have to take it every week?

How do you get this medication??

feel like we should wait another 5-10 years to mass perscribe these until we are very sure they dont cause pancreatic canc. thats the worst way to die imo

According to my scale, I've lost 35# and gained 14# of muscle mass. I am working out 5 days a week and taking Semiglutide.

Yeah, you can gain muscle mass back. Get your @$$ in the gym while taking it. A lot of people want to sit around still and do nothing which is crazy to me…

Great ! the adipokinin mechanism was NewZ to me... i don't like to debate` science but the studies you bring up may or may not be statistically significant. so many factor in muscle growth that have nothing directly to do with diabetes or the deeper iisues in metabolic syndrome... for me i notice the side effects when eating incorrectly ie ,, negative reinforcement

So the answer is yes you do lose muscle mass. Like you said you can counter that by resistance training, proper sleep and eating protein rich meals. However they don’t do these things and that is the problem. They can’t eat because appetite is suppressed. They don’t sleep well because nor do they exercise because energy levels are low. Not to mention how common the GI adverse events are. I saw my wife’s muscles melt before my very eyes. Insulin generally favors muscle gain so naturally when you are eating high glycemic meals your insulin levels remain elevated so you won’t have muscle loss. Yes, when you stop eating these foods and lose weight you will lose both fat and muscle but losing weight naturally is still better because these is way less muscle loss. It is sustainable, no GI symptoms and no appetite suppression so you can still eat clean and well.

The 3 tips to maintain and improve lean mass apply regardless. It remains to be seen if these drugs will be used for a lifetime once started. Probably not, therefore without good habits including these 3 tips, the weight will likely be regained once off of the drugs, just like fad diets.

I would absolutely agree that the GIP And gLP1 could cause muscle loss but if you train eat a lot of protein and vegetables if you desire the vegetables take your creatine you will not lose muscle but you need to get the calories in just the same

If you don’t change your crappy diet, eat sufficient protein, do cardio and weight bearing exercise sure you will lose muscle along with the fat. Not rocket science if you do it right it works brilliantly. I’ve dropped 11kgs in 7 weeks on monjorno with a good diet and appropriate exercise.

I'm sorry it's me again. I just like to let you know doc I do not take sugar meds anymore or high blood pressure or cholesterol pills. So my insurance is gladly paying for 100% of this medication high blood pressure medicine was very high and taking this stuff for the rest of my life I am so glad that I might be losing some muscle cuz I can build that up. I don't have to worry about all this medicine to take because I'm fat but I'm not fat I've lost weight. Losing weight in Florida so I will be living little bit longer

Muscle loss is not a good thing, even if proportionately fat loss is greater. The heart is a muscle.

Im on mounjaro its hard for me to exercise because of cervical and lumbar fusions and damage still left what can I do to help

I’m on Mounjaro down 150 pounds and scared to get off. How should I do it

I don't know the math, but at 335lbs, I could still do 35 regular push-ups. I now weight 264 and I can't do 5....

Your are so awesome Dr. Mike. And we miss you when you take breaks. Our GOOD Dr. Mike!! ☺️🙏🏼

Just exercise and lift weights along with the weight loss?

Please talk about monjourno and fasting for 4 days!!! Please look into this for me. Because fasting is hard but on these drugs it’s super easy. I can go not eat for days but I’m afraid to do it because of getting the protein to not lose muscle mass.

I have muscle wasting now. But I'm 60 so.....

Couldn't you just take CoQ10 and Gynostemma pentaphyllum to boost the mitochondrial and AMPK function?

I feel like doctors are going to be eating their words soon in the "miracle drugs" like ozempic.

So this drug destroys more fat than it does muscle so does this drug also know the different between the heart muscle and a leg muscles I don't think SOOO

I used to like Dr Mike more. He’s really gotten behind these novel drugs as a seemingly miracle drug we’ve all been waiting for. I’m not dismissing it’s benefits but it’s too novel to know the real long term implications as with most “too good to be truths” go, there’s usually a trade off we didn’t foresee.

I'm so sorry I can't remember the name in a year to two years they're going to have a brand-new shot. Not that bad side effects that we get with these other ones. They're building right now with building for they can make this medication. It's for weight loss so you don't have to have sugar problems in order to get this. I can't wait I use that for maintenance. But Google it the shock coming out in a couple years for weight loss. I had it on the tip of my tongue. Sorry people maybe y'all can Google it up and see I already been researching it😊

I had to stop that drug I lost all my strength my appetite and has caused mental health issues

Dr Hansen, have you ever done a video on SARMS or maybe willing to do one? Harm reduction and all? Idk if RU-vid allows it. We keep talking about the weight loss products that started as meds for other reasons, maybe SARMs and peptides? Most web pages just say the same stuff and I'm wondering what the docs think of it all.

Really good information

Unequically with me, I lost a good amount of muscle mass. Also, the loss of fat weight with muscle mass caused me to have angel wings....loose and wringled skin on my arms and my pectoral muscle (I am maile) as well as a great loss of leg size. In my case I lost too much weight too fast. 60lbs in a little over 5 months. I am now off the Ozempic and have been lifting weights to regain my muscle loss. Also, during my time on Ozempic I was on TRT, so the weight loss was not related to a lack of androgens. I had a lot of severe stomach cramps and constipation which aided my not wishing to eat and so I ate one small meal a day. Now I believe if I had to do this again, I would have gone with eating 3 smaller meals a day and a much slower weight loss. What I have done while off Ozempic is...GO BACK ON LOW DOSE OZEMPIC. I gained weight back at almost physiological impossible rates....a pound a day, or a two pounds every three day average. AND I was not overeating. Ozempic has to have either an undisclosed effect on mediator of overall metabolic process e.g. thyroid levels (which goes along with an increase in medullary thyroid cancer) So after about six weeks I started 'micro-dosing' at .17 mg/wk and it helped to me both lose a bit of the weight I had gained but did not cause the side effects which made it impossible to exercise. To be specific, when you have not defalcated in over a week and your intestines are in knots, lifting weights or any type of cardio is almost impossible because YOUR TOO SICK. And finally BTW, I am diabetic and the Ozempic was given me for diabetes. As you know diabetes has its own risk of serious diseases and I don't believe Ozempic should be preferentially prescribed off label for weight loss only.

These vs sarms?

It’s not rocket science. If you lose weight this quick you’re going to lose muscle as well. Focus on weightlifting while on it.

Are Statins bad for your body? What can a doctor prescribe instead?

Muscle has fat in it and water and blood?

The majority of people today are not getting enough protein in their diets, especially women and are losing muscle. Women on these drugs look the worse because they're losing so much muscle...when they didn't have much to begin with. And they're most likely not lifting weights, so this video was not tailored to address women on ozempic?! nothing about how hormones come in to play, pre/post menopausal women, etc. Sad to see medical professionals like yourself talking about debunking the myths when for women and men are being put at higher risk for osteopenia due to muscle loss. Because with scarocpenia or muscle loss there is bone density loss. Muscle loss of any size is detrimental to your overall health. Hooray for fat-loss but not at the expence of your muscles!!!

I loss 20lbs of muscle, went from 30% to 47% fat in 8 weeks on Ozempic. Now I’m so weak!! Back at the gym trying to get my muscles back. I had 122 lbs muscle now 95lbs muscle

Thank you for the thumbnail!!! 👍

the idea that a drug that causes sarcopenia will make you live longer is just absurd off the bat.

FURIOUS! I have lost at least 40% of my hair in length and thickness! I have LOST ALL of muscle mass in my buttock. I literally have NO MUSCLE in my buttock, sitting directly on my tailbone! IT HURTS! All I have on my buttock is thin, wrinkled skin (like a 90 year old). Finally a few weeks ago I suffered "sulfur burps" that lasted a few days. A.K.A. ROTTING FOOD / WASTE in my gut. Eyesight is also quickly becoming worse! I am going after the maker of "mounjaro"!

u should invite attila on your show.

❤😂

Maybe you can be more honest about the covid vaccine rather than trying to sell drugs. Kind of suspicious you spewing out videos selling this product all the time.

Michael...you should be ashamed of yourself...using a sexy photo of yourself for the thumbnail. LOL Great video as usual Dr. Mike.

It is absolutely horrible how obvious it is that you were payed by those companies. Freaking horror.

Monjourno gives me no appetite which I’d like to take the advantage to fast for all the wonder benefits that I want to turn on. Please talk about using these drugs to fast 3 to 4 days out of the week.

Please talk about doing a 4 day water fast when on monjourno? Because I’m not hungry so I want to take advantage of this time because no hunger pains.

Can I do a 4 day fast when I start monjourno? Because I’m not hungry so I want to take advantage of this to build Keyon’s

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