www.explorebiology.org/summar...
This video describes the Nobel Prize winning discovery by David Baltimore and Howard Temin of reverse transcriptase, an enzyme that copies RNA into DNA. Retroviruses, which have a genome made of RNA, use reverse transcriptase to replicate. This discovery came as surprise because the widely accepted Central Dogma postulated only a one-way flow of information from DNA to RNA to protein. Reverse transcriptase later played a major role in biotechnology industry, providing a mechanism for cloning DNA from cellular RNA and making cDNA libraries. Learn more reverse transcriptase and viruses in Mike Bishop's Narrative on Cancer Genetics in The Explorer’s Guide to Biology (explorebiology.org/summary/genetics/the-genetic-basic-of-cancer).
29 сен 2019
