The Bioluminescent Gaming PC

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By genetically modifying some E. Coli we make a PC glow. Really.
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MUSIC CREDIT
---------------------------------------------------
Intro: Laszlo - Supernova
Video Link: • [Electro] - Laszlo - S...
iTunes Download Link: itunes.apple.com/us/album/sup...
Artist Link: / laszlomusic
Outro: Approaching Nirvana - Sugar High
Video Link: • Sugar High - Approachi...
Listen on Spotify: spoti.fi/UxWkUw
Artist Link: / approachingnirvana
Intro animation by MBarek Abdelwassaa / mbarek_abdel
Monitor And Keyboard by vadimmihalkevich / CC BY 4.0 geni.us/PgGWp
Mechanical RGB Keyboard by BigBrotherECE / CC BY 4.0 geni.us/mj6pHk4
Mouse Gamer free Model By Oscar Creativo / CC BY 4.0 geni.us/Ps3XfE
CHAPTERS
---------------------------------------------------
0:00 - Say hello to the Angler Fish
0:37 - War Thunder
0:50 - LTT Intro
0:58 - What is Bioluminescence
2:04 - Intro to Genetic Engineering
3:15 - Biotechnology, cooking show style
4:51 - Linus playing with E. Coli
5:44 - Test tube glowing
7:15 - Purification feat. His-Tag
8:30 - Glow #2
10:56 - Filling the loop
13:42 - The Bioluminescent Gaming PC
14:23 - What this is actually used for
16:22 - War Thunder again!
17:06 - Outro

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12 май 2024

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Комментарии : 4,4 тыс.

@stephenjeremy5985 2 года назад

Ive never thought that the day would come where Linus explains DNA translation and PCR to us

@filleswe91 2 года назад

Yeah, usually it's been all about PCMR and RDNA talk instead.

@EhmJB 2 года назад

Just wait until the "Installing the Intel Cognicyte i59 BioCPU" video he releases in 2063. It's gene splicing all the way down.

@georgejosifidis 2 года назад

He just relayed the information like a parrot making noises

@maciejjabonski833 2 года назад

Technically, he explained TRANSCRIPTION, not translation (geneticist here). Transcription - DNA -> RNA Translation RNA -> Protein

@TheIceThorn 2 года назад

@@maciejjabonski833 it's a quesiton that bohers me since very long... but since dna "evolved" from RNA, now it came to be? An error of transcription? Ther might be some sort of bacteria that has reverse rhybosomes which reverses the reaction and forms new DNA instead of RNA? yeah, i've already tried to find th e answer by myself or I wouldn't be asking, i swear.

@AYgameZ 2 года назад

Fireflies: *look what he has to do to mimic a fraction of our power*

@kyzinga266 2 года назад

I grant u my chuckle

@Nxrreshh_ 2 года назад

😂😂😂

@Nxrreshh_ 2 года назад

@@kyzinga266 🤣

@kingchauvinthehate7030 2 года назад

look what they need*

@jon4715 2 года назад

Great comment, and true. I've read this before, where?

@ajmatt 2 года назад

As a molecular biologist I can die peacefully now listening to Linus's voice explaining cloning and bacterial transformation.

@TheBatracho 2 года назад

Dude, same here, molecular biologist here and PC fan who never expected hearing Linus talk about His tags lol

@farhannajme7542 2 года назад

Samee as a marine microbiologist Linus gave a pretty good lecture there.

@showjjumper 2 года назад

But cut the part where he drops the eppendorf pipette 😭😭😭

@johnkaba2593 2 года назад

@@showjjumper This is where I died inside

@Winter_huntsman 2 года назад

About to graduate with a microbiology degree in a few weeks and completely agree. It’s so neat hearing him talk about lab techniques that I learned in classes and performed in labs so much.

@mumble3535 2 года назад

"Yeah, I have this massive algae bloom in my tank at the moment" "Damn dude, are the fish okay?" "What? Nah dude, my rgb algae has really come into its own and its looking sick" I support this kind of bio engineering

@spamreciever4208 Год назад

I wanna live in the CyberPunk future where I can have a bloom of pet bio-engineered bioluminescent bacteria in my computer full time.

@Julian-og3ps 2 года назад

That moment where he turned on the pump was legitimetely the coolest thing I've seen in years. Made me feel like a kid going to one of these places that let you do supervised science experiments again.

@shadowpenguin3482 2 года назад

12:45 for anyone who wants to rewatch it

@fantasticparrot602 2 года назад

@@shadowpenguin3482 a bit later actually for the when he turns on the pump 13:51

@markj9860 2 года назад

I much preferred the part where he started pouring the bacteria into the spherical reservoir, that slow blue spill down the sphere is just gorgeous. But yes, this few minute segment is one of the greatest things I've seen in this channel.

@solarbirdyz 2 года назад

@@markj9860 YES YES YES that was AMAZING. It literally looked like an SFX shot but was real.

@FlyingPenguino 2 года назад

"Oh god" - Alex

@pranaygohel4630 2 года назад

"Tech Tip: Don't get E. Coli" Yeah, that would be a good idea.

@BrianTeague00 2 года назад

Bioengineer here: The strain used in the lab is quite different from the one that makes you sick! You could drink a culture of it, and it might give you a belly-ache, but not much else.

@furkell 2 года назад

Not exactly tech, but a good tip nonetheless

@rwhite9994 2 года назад

E. Coli is natural in nature and most all of us have it somewhere at any given time. The kind that makes us sick, or takes over is different. That e coli is as safe.

@Giangero21 2 года назад

what the ..... i don't think this is a coincidence

@emilie6466 2 года назад

@@DemeDemetreEscherichia Coli

@pedroguincho6580 2 года назад

Easiest like of my whole life, It’s amazing seeing Linus combining my two most loved subjects, biochemistry professionally and Tech as an hobby. What impressed me the most was how clear Linus’s explanation was of such a complex topic. Well done guys, you really outdone yourselves with this one!

@MoChuang343 2 года назад

What kind of biochemistry do you do?

@filleswe91 2 года назад

More scientifically broken down videos like this please! I didn't feel like an idiot and I enjoyed the science lesson. Not just because it was Linus. Fun project, LMG!

@filleswe91 2 года назад

@Phoenix Trinity what?

@crumpybird4281 2 года назад

@@filleswe91 what?

@TheHookUp 2 года назад

I taught AP Biology for 15 years it's sad how much better your animations are than anything teachers get access to with a textbook. This is totally not a dig because I loved the video, but If I was still in the classroom I'd 100% use this video with my students to be able to go over the hand wavy parts and have them find the couple of inaccurate/incomplete sections of the process. Science Linus gets at least a B+.

@volklii 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oescB0NyejI.html

@StripesOO7 2 года назад

Exakly my thoughts with a bachelor in Biology (bachelor-thesis in genetic) . Beautiful animations that are 100x better than every old textbook but some parts are either missing or slightly wrong. But nevertheless accurate enough to be understandable and having an educational effekt on the „average“ viewer. 👍

@majsstenen 2 года назад

Just make sure to correct it first, that DNA repair animation ain't right :3 // Biotech engineer

@reyanak9818 2 года назад

@@StripesOO7 You need a bachelors degree in spelling

@Kitulous 2 года назад

@@reyanak9818 don't need to be a douche in the comments. Maybe they're German, that's how they spell "effect" and the languages are pretty similar enough to mix up the words.

@matiastripaldi406 2 года назад

Am I actually seeing PCR, recombinant protein expression and bacterial culture in an LTT video? Is this a dream? I study biotech so this is my bread and butter, never thought you guys would venture into it. Amazing work!

@mycosys 2 года назад

likely the most culture we'll ever get on an LTT video ;)

@goldcd 2 года назад

You are - and I liked it!

@luxbio 2 года назад

so glad you liked it! what area of biotech are you studying?

@FranciscoTC 2 года назад

As a med student who loves tech, this definitely tickled my pickle

@matiastripaldi406 2 года назад

@@luxbio well i'm in 3rd year of university (out of 5). my uni is mostly geared towards research work (which is what I'm interested in) but it also prepares you for if you decide to go into industry (such as producing insuline for diabetes patient en masse with genetically modified E coli). After i graduate i'll probably go into research hopefully in something health or human biology related, there's a bunch of really interesting stuff popping up. Most of my professors are researchers too so they tell you about the work they're doing and it just sounds awesome to work in. But tbh molecular biology in general fascinates me so i'd be happy to work in any lab (with bacteria or eukaryotes) as long as it's not plants haha, plants are incredible but kinda boring

@Cobyc5150 2 года назад

I want more science lectures from linus, he's surprisingly really good at explaining everything. He uses some very easy to understand examples.

@bigboij3027 2 года назад

The magic of writers

@SnifferSock 2 года назад

2 things: This is sick. The mixing effect is good enough to replace CGI.

@PetePeteRepeat 2 года назад

Linus, get your team to do some research and create an LTT Lab Coat, with elastic sleeve cuffs, and quick-release snap buttons... as a Chemist, I would 100% buy one

@hellowill 2 года назад

Reminds me of his older videos, around 2013, when he would wear a lab coat for PC builds

@Aviyara 2 года назад

Quick-release snap buttons, three pockets (with the pen subdivision on the chest pocket) and in-garment "cable management" loops for threading wired earphones. Forget buy them, I'd preorder them and pay up front.

@volklii 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oescB0NyejI.html

@Jeffmylife 2 года назад

As not a chemist, I also would 100 percent buy one

@ron200088 2 года назад

Now that they have the technology, they could also create their own brand of bioluminescent "RGB" coolant. ;)

@damustermann 2 года назад

Linus DNA tips - really cool that you guys go into a lot of detail about the background of this.

@_yuri 2 года назад

amd RDNA

@MrSerella 2 года назад

@@_yuri RDNAvidia

@jonathanmoelester448 2 года назад

@@MrSerella GeForce RX 3090 XT

@sullychow4123 2 года назад

Never expected LTT to go all Thought Emporium but love it. More of this whenever you guys can please.

@thecomfyshirt 2 года назад

It SO beautiful!!!! I wish it was practical to actually have on of these. This is why I love LTT. Today I learned about chemistry on a PC building channel. What a great vid!

@xanthosjason9530 2 года назад

Bioluminescent bacteria: *exist* Linus: "slap that sh*t in a computer!"

@hojiry490 2 года назад

@Sahara Gurun no.

@leonardtao4457 2 года назад

Next step: RGB bacteria

@ThisIsTechToday 2 года назад

If only science class was this exciting when I was in grade school, lol

@doggoonus1414 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-H-BuXc18fQI.html

@desmanbotts4244 2 года назад

Thats crazy because I learn about rna and dna last school year.

@dadsfriendlyrobotcompany 2 года назад

@@desmanbotts4244 it gets even crazier. I got my degree in genetics and genomics

@experimental0000 2 года назад

Little show called Bill Nye the Science Guy

@markscheuerman7962 2 года назад

What grade school is going to be able to afford pcr equipment?

@CsTvInc 2 года назад

truthfully, I love it when they head out and meet up with companies with cool ideas and goals. these are some of the best type of videos

@DrivenKeys Год назад

Perfect reservoir for this, and great camerawork. Absolutely amazing developments. Keep making these videos.

@ln1721 2 года назад

this is just upgraded RGB and i love it

@gliderman9302 2 года назад

Ikr? But it adds style points tho

@basil127 2 года назад

eco friendly rgb

@brodyenli 2 года назад

More like upgraded B

@subboytris8946 2 года назад

RGB 2.0 HAS BEEN RELEASED

@paulgray1318 2 года назад

We're just getting used to 4 wire RGB controller's and now they want to add DNA controllers - in the 60's you made your own colours :).

@YeahRightMCD 2 года назад

A whole video on environmentalism-meets-technology? Keep em coming, big guy.

@pdabrowski4831 2 года назад

Linus already has more going on in the environmentalism space than most tech reviewers/creators, there's been a good amount of highlighting sustainable packaging in their unboxings and his recent serious investment in the right-to-repair campaign with Framework Laptops shows a commitment to the future.

@YeahRightMCD 2 года назад

@@pdabrowski4831 You're not kidding. Most tech content creators realistically don't do enough to push the efficiency side of progress, as much as the *RAW POWER* side of the coin. P.s. A+ power move investment on framework. Right to repair, and Wu Tang, are for the children. P.p.s. #$_& a full landfill *throws up fake gang sign thing, or whatever*

@volklii 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oescB0NyejI.html

@MiddleofKnowhere 2 года назад

Please keep spotlighting initiatives like this with sustainable and environmentally friendly products. The tech industry is probably one of the most wasteful from materials for the actual product to the packaging (all that plastic!). It's something that ought to change and some companies have been doing better I've noticed.

@bkrc123 2 года назад

Thank you for giving nyoka labs recognition. Will be following their progress.

@NathansWargames 2 года назад

Linus, we need a legit LTT Lab Coat for when we're doing computer "science" like this.

@simplybloxxed 2 года назад

the amount of ads here though

@HattertheThird 2 года назад

This PC lures in gamers with its pretty lights to prey on their free time

@mirrorsandstuff 2 года назад

This is one of the neatest projects the LTT team have come up with recently and I really hope whoever led the project's research is proud of themselves. The organic chemistry was well explained and the level of detail was at the right level whilst still being engaging.

@jessterbal 2 года назад

Great collaboration, please do more like this!!!! Thanks!!!

@fireaza 2 года назад

It was very brave of the staff to hand Linus their expensive scientific equipment to hold, knowing what might happen.

@ikonikian475 2 года назад

How is it brave? He's rich. He breaks it he buys it lol

@zatoichi188 2 года назад

PCR machine ain't that expensive, and once you have the actual engineered organism you can you usually produce buckets of it for pennies. The expensive bit is the actual engineering.

@highping5137 2 года назад

@@ikonikian475 do you know how much money it takes to make a business he probably only has 50% more money than the averege person so he would be broke if he broke one

@Jawad.1 2 года назад

Nothing 'might have happened'. Linus knows what he does. He's one of the most intelligent and responsible people I've ever seen.

@joetownsend6325 2 года назад

@@highping5137 he has a business and assets, to say he would be broke because he loses the money in his pockets is patently false. It simply means he can't buy a new car until next week.

@argon552 2 года назад

As a microbiologist that specializes in bioinformatics, this was one of the best colabs and video that LTT ever produced. Well done guys

@StripesOO7 2 года назад

Nice to see someone else doing the same thing. I am still studying but switched after my bachelor thesis in molecular biology/genetics to bioinformatics as my master 😅👋

@argon552 2 года назад

@@StripesOO7 in that case cheers 🤘

@FriendBe 2 года назад

This is pretty amazing ngl. The applications for something like this has me pretty excited for the future.

@thekraken8him 2 года назад

This has got to be the most interesting PC build I've ever seen. What a creative idea, and great execution. The Techquickie style explanation of the DNA reactions was an excellent touch. Also, 9:47 should be the thumbnail for this video.

@lecuyermarcandre 2 года назад

As an immuno and microbiologist, this is by far the best content ltt could have produced. Great vulgarisation of the scientific principle behind it as well. I would like twice if I could.

@dkofkloveeqisgreat6123 2 года назад

virologist and molecular biologist here, this might help some begin to understand how mRNA vaccines work as well. Tip of an iceberg but a start. other than that is there a version of these products that has both molecules stable before and after binding that can reveresed by say the application of heat. so in the cool part of the loop they bind and emit light but on the addition of heat dissacociate ( pass through heat block over chip), rinse repeat. i guess it depends on how stable the protein or capable of refolding after the techicaly heat denaturing. awesome work either way and shows molecular biology/ bio chemistry off well, in way lots can see and understand. ahh beer and now i cant stop thinking grr

@marcosmedia7463 2 года назад

Linus: We make PC that glow War Thunder: This is worth a sponsor

@tomasalmeida2940 2 года назад

Nah but is a minor detail

@haydenw8691 2 года назад

Good thing you can block sponsors now. Makes the videos much better.

@Auroric 2 года назад

This is so rad! Stoked to see Nyoka getting some good exposure, would love to this take off

@luxbio 2 года назад

Thanks Auroric! How had you heard of us??

@keithvassallo 2 года назад

This was one of the best and most interesting LTT videos I’ve seen in a long time! Well done and give us more!

@EclipsaMyrtenaster 2 года назад

"Haha. I made you guys watch a Science lecture disguised as a computer video." That ticks off two things on my list.

@okabehakaze6416 2 года назад

As a molecular biologist that builds computers as a hobby, I just wanna say this build looks awesome

@ninjashuriken 2 года назад

fkn mad scientists

@pauliewalnuts2527 Год назад

Why don't you do something similar?

@Swordsmanjan 2 года назад

As a biochemist working in enzymology I truly enjoyed this episode. Great job everyone, both for the entertaining content and the high degree of scientific accuracy. Seeing educational content like this is great!

@WendtKyle 2 года назад

This and the Framework laptop video from a day or two ago are a new and really awesome direction for this channel.

@thanhvinhle2893 2 года назад

Linus holding biology chemicals. Everyone: nervous sweating

@kemalardaayar 2 года назад

conspiracy theorists: oh shit L virus is coming!

@clydemasterson1129 2 года назад

Next week: Can Linus power a gaming PC with a Tesla Coil???

@cyber_hacker 2 года назад

@@kemalardaayar are you talking about that L-vid-2021 (aka. Linus video 2021)

@kemalardaayar 2 года назад

@@cyber_hacker oh

@zerumsum1640 2 года назад

even though i knew it'd be lab bacteria that are (relatively) harmless, I still cringed when he said it was e-coli. We get examples all the time of why Linus is a bad guy to pass dangerous/fragile things.

@optillian4182 2 года назад

Linus really woke up one day and said "hmm yes I'm gonna put glowing germs in a computer".

@optillian4182 2 года назад

@CHIYOKO Begone, bot.

@yknx4 2 года назад

He is running out of new things to put into computers

@dkursada 2 года назад

It was such a fun episode, legit props for the explanation w/ great animations! As someone long time PC enthusiast who's just started studying biotechnology, this video is such an eye opener for me, for the bioluminescent gaming PC is such a cool demonstration of what happens when you bring knowledge of two seemingly distinct subjects together with a fun idea or two. What you do doesn't always have to be practical. A PC with glowing water cooling is just plain awesome. It's good getting to know Nyoka Design Labs folk, too. They're doing awesome work with reusable and longer-lifespan material! p.s: Linus Biotech Tips lol, I could get used to this. Would be such a fun channel

@rusinsr 2 года назад

Love these sorts of videos! Really interesting and different from the usual stuff :D

@thethoughtemporium 2 года назад

Nyoka's stuff is so cool. I've seen their stuff go by a lot in the various bio groups. It's a neat idea for sure, though hard to say if they'll be successful. Don't get me wrong, the idea is clever, but scaling biotech is really really hard. Take it from someone literally trying to scale up a lab scale biotech project to industrial scale. It's very much non-trivial, even if the idea is very simple. Also the claim you can drink it is mega sus. And they will need a huge amount of certification that there is no contamination of the live genetically modified organisms in the liquid or it would be a felony to dump it down the sink. The EPA would be furious. And if it's just a lysed ecoli suspension it'll always smell awful. So ya, they've got some stuff to address. Also, I really hope those were "stunt" pipettes, cause those are expensive and dropping them like that will wreck them. Edit: They replied and clarified that they've already addressed all this, and this was just the demo version, so nvm I guess. Glad they're further along than I realized! Never gonna complain about more cool biotech companies doing cool stuff.

@timfallonphd3085 2 года назад

Yep, I totally agree on the difficulty of implementation of bioluminescence! Biology is a whole different ballgame from tech, as you well know! And yeah, dropping the pipettes not ideal but in my experience not too bad. Every biologist should know how to calibrate / validate their pipettes & do it whenever they have a suspicious fall like this.

@ScreenNameLmao 2 года назад

My fav biotech youtuber in linus comments? Is this a crossover episode

@thethoughtemporium 2 года назад

After what I just spent on pipettes, there's no way I'd throw them around like that. But that's just me. I do have a cheap chinese set though that are specifically for shots like that where you want to joke around. But I film bio stuff all the time. I assume for them the publicity of this video outweighs concerns about pipette calibration though, so w.e. To each their own.

@timfallonphd3085 2 года назад

@@thethoughtemporium Not to worry, I'm sure Linus is working on a follow up video about calibration of that dropped pipette right now! Right Linus?? Linus? Haha but more seriously: people get all up in arms about mistreating instruments - either pipettes, or things several orders of magnitude more expensive like LC-MS instruments. IMO, minor mistreatment and yes occasionally breaking them is part of the natural learning process, so my philosophy is scientists should be comfortable with pushing the envelope, potentially breaking things, & evaluating when they need to be fixed & how to fix things, and not be afraid if they did break something to ask for help. I can understand in self supported research that changes the equation a bit as each dollar available is more precious due to the limited funding sources, but at least in science education I lean towards the response being "that's okay, let's see what happened". Or at least that is what I tell myself to feel better about when I accidentally drop my pipettes :)

@matiastripaldi406 2 года назад

@@thethoughtemporium i thought the same, was really surprised to see the team handling expensive lab equipment. But i guess they're within budget

@DerekMorrelli 2 года назад

Having a bachelors in biology and a masters in chemistry, this is possibly my favorite video I've seen from LMG. Great job at explaining the scientific process, pretty much as simplified as you can get and still describing the process accurately. You've just made RGB obsolete!

@acrythm8316 2 года назад

Wow. This looks amazing, love the video man!

@jora9655 2 года назад

I absolutely adore how you give us the background knowledge to understand how bioluminescence works and even how the gene manipulation involved functions. You're a tech channel, but you have such a broad horizon. Love it!

@mindgame112 2 года назад

As someone wo used to work in Molecular Biology: Linus dropping the pipet: SHIT now you need to recalibrate it...

@mayanksoni2399 2 года назад

forget recalibration, my lab ones would just shatter and break

@MitgliedT5 2 года назад

If we broke a pipette in the lab, we had to go to the professor and pay for a new one ourselves, depending on the situation.

@arksy8703 2 года назад

@BIG ASS you will never be a real woman, 48% yourself

@Spork0 2 года назад

@@arksy8703 its a robot btw. not a real person

@ilodabomb 2 года назад

Dropped so many pipettes in my life... recalibated a whopping number of 0 pipettes 😄

@20quid 2 года назад

I love how he's holding a model of a tardigrade when he's explaining how they get the genetics from a crustacean and put it in a bacteria, neither of which are tardigrades.

@Kuli24000 2 года назад

Nervous laugh.... yeah that.

@la24dogg21 2 года назад

Lmao I knew I would learn form someone here

@paigewhitehead2157 2 года назад

yeah we didn’t have a model of those on hand! We brought our tardigrade in the hopes it would make it on screen - it was hand made by someone on our team 😆

@benezzy 2 года назад

I was waiting to see when the tardigrade Linus was holding was gonna be talked and it just never happened lol😂

@tomrl6674 2 года назад

@@paigewhitehead2157 tardigrades are pretty cute

@andresleon-vargas3603 2 года назад

This was awesome. Great job explaining the science, not an easy task. I'm studying bioengineering in school right now and find this type of content particularly interesting and fun.

@kristycyw Год назад

That was an impressive summary of DNA transcription, translation, RNA transcriptomics, PCR and genetic engineering

@DVMJon 2 года назад

I LoL'd literally. When I realized Linus was giving an actual lecture in polymerase chain reaction (PCR) 😂

@Grocel512 2 года назад

Linus next week: "Let's overclock and water cool a PCR machine." **shows live Covid-19 samples** "This will be our benchmark!"

@occasionalglory5261 2 года назад

Linus: "Traditional glow sticks are full of toxic material." Me: *Starts having flashbacks to cutting open glow sticks and smearing it on my face as a kid*

@willy.c 2 года назад

I remember well biting into one and having the liquid shit in my mouth to scare my friends...p

@aarontimm 2 года назад

bruh WHAT

@hpsmash77 2 года назад

tf!!!

@Soosss 2 года назад

i used to bite into them like an idiot

@t_y8274 2 года назад

One part carcinogen, one part high concentration peroxide. Yum!

@vk.7165 2 года назад

This was one of the most interesting videos in a while, really fun and informative, and also gives a shoutout to hard working scientists. If you can, do more of things like this :)

@MakDemonik 2 года назад

As a student of Biotechnology I have to say you did a great job of simply yet effectively explaining the whole process of cloning genetic material via the PCR method and how the entire bioluminescence process works. (You could have just mentioned that each cycle gives you orders of magnitude more material - doubling it every time - than just having "more" in general) Loved the video.

@mullokakkarin 2 года назад

I actually really appreciate as ex Lab worker, that once in a while you make science videos. We actually need more people to get people interested in the science topic and also influencers to put more emphasis on importance of science... I believe that even those 'once in a while videos' can cause some changes for better in that field. (Believe me or not but scientists are in many cases underpaid, and they do not want to invest more than 10-15 years of gaining knowledge to not earn enough to live like a human)

@TheKeKApex 2 года назад

imagine if we put the ability to regrow limbs in humans, how many amputee's we can help alone. along with other things that can be cured with designer viruses. it's wild it's even a debate to keep pushing on this.

@volklii 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oescB0NyejI.html

@wobblysauce 2 года назад

While YT is good and all, more people in Science is not a bad thing.

@joosts4085 2 года назад

These videos are such an amazing lesson in disguise. The amount of people that now know about this that otherwise wouldn't hear about this for months or years is amazing and will hopefully boost this kind of research.

@timfallonphd3085 2 года назад

I totally agree. The type of reach this video has is incredible! Millions of people learning about bioluminescence! So great!

@Haskellerz 2 года назад

LTT in 2030, we are gaming on the latest Ryzen 90000 bacteria processor attached to 1000 TB permanent DNA storage

@TheBackyardChemist 2 года назад

@@Haskellerz DNA tape drive. Retains data integrity for 10 000 years at -80 °C.

@AD-de2sl Год назад

love the fact that you give great ideas a chance on your channel ! :)

@SparklySpencer 2 года назад

This was a fantastic video, and I hope you have more like this in the future

@benjaminkocsis2983 2 года назад

As a researcher in a microbiology lab, I am so happy LTT made this video. He did a pretty good job of explaining pcr in lamens terms. I didnt expect to see the wonders of microbiology shared by a tech channel but I am very glad they did.

@volklii 2 года назад

ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-oescB0NyejI.html

@zackriehl8079 2 года назад

"I will not be making any *AHEM* unscheduled visits to the bathroom." - Linus. This implies the existence of SCHEDULED bathroom visits. Hmmmmm

@sphrcl. 2 года назад

Bro someone copied this exact comment word for word and they got a lot more likes than you because they have a check mark next to their name

@zackriehl8079 2 года назад

@@sphrcl. oh well. As long as I'm the og, I don't care.

@stefa4013 2 года назад

I mean on work days I have set times I go to the bathroom so yeah you can totally schedule them

@cubeventure 2 года назад

@@zackriehl8079 i respect that you don’t care

@clared5812 2 года назад

@@sphrcl. why does it matter, internet points are completely meaningless

@madhazza64 2 года назад

I really enjoyed this! I love science, Linus delivers things so well and I honestly wasn’t bothered at all that computers were hardly involved. I’d super appreciate more videos of this style thrown into the regular mix more often ☺️☺️

@nolanmanning3749 2 года назад

I love this and hope it takes off to reach multiple millions of views! Would love to see more demo type videos

@Ulandos 2 года назад

7:12, Linus deciding whether or not he's holding a condom or E.Coli

@trailfork7815 2 года назад

I'm still bothered that it looked like a used condom

@pepkin88 2 года назад

linus sex tips

@randomblock1_ 2 года назад

4:52

@adityadivine 2 года назад

Me who never got a chance to use it. Ahh life sucks

@106640guy 2 года назад

COOOOM

@devinou-programmationtechn9979 2 года назад

Linus : "Minor details like our sponsor : war thunder ..." War Thunder : "Am I a joke to you ?"

@zUnderscore 2 года назад

tbh war thunder is a joke

@nihouma11 2 года назад

This looks so cool, have to watch later, but keep up the amazing videos!

@carnotit 2 года назад

this vid is awesome! congratulations linus for bringing such great content.

@Verlisify 2 года назад

Ok this is one of the coolest things I have ever seen and exactly what I imagined the future would be like

@botted1193 2 года назад

deez

@an456pop3 2 года назад

nutz

@LightningSquad 2 года назад

I uploaded my Face Reveal...

@raulll95 2 года назад

Just think having the Bioluminescent liquid inside the PC and having the Glow paint on the PC case - ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-Y_OIK2IBqXE.html . The effects from TRON movie are not far from having day to day near us

@Denofu 2 года назад

cringe

@MrWestonO 2 года назад

"Alex, you had ONE JOB." *proceeds to list 5 jobs* Edit: yes guys i know this was a joke but its still funny

@Tosti_bakker 2 года назад

I think that was the joke

@duatchol7710 2 года назад

I’m completely lost as to whether you got the joke or not, lost in internet translation I guess

@MrWestonO 2 года назад

@@Tosti_bakker well ye

@MrWestonO 2 года назад

@@duatchol7710 i did

@kehnxii Год назад

This is the first time I have ever seen this pop up on recs and I love it

@radspiderjackson 2 года назад

cool intro breakdown, i didnt have to skip thru to the good stuff

@FranciscoTC 2 года назад

If you want to do this at home you'll only need: *200 dollar variable volume pipette*

@timfallonphd3085 2 года назад

There is always Ebay :) Rather than a variable volume pipette, a standard medicine dropper, releases about 20 to 50 microliters per drop - more than enough accuracy to do this type of experiment at home.

@zechsta28 2 года назад

you could use a thin straw as long as you make a good estimate on the volume. a bikewheel as centrifuge, and pots and pans with different temp water in them for the thermalcycler (Its gone take a while though getting your sample from pot to pot 40+ times)

@timfallonphd3085 2 года назад

@@zechsta28 Yep! I think there are lots of ways to make this work at home, without the "professional" equipment, just have to get a bit creative. After all, biologists in the 1800 - early 1900s had pretty crude tools but were able to figure out a huge amount of stuff!

@kehrnal 2 года назад

Also if you used the centrifuge he showed, you'd be spinning small amounts of that culture all day long... Not 10 min

@adamengelhart5159 2 года назад

At least the column is only five cents? Oh, wait. I think I might have that confused with something else. :-/

@DrNarf 2 года назад

LTT, you're laying the groundwork for producing better, higher quality, educational videos than McGraw-Hill when it comes to Biochemistry. If you need someone with an MS in Biochem, lmk because, yeah. Awesome work. We need more content like this. I already enjoy your "tech longer". Go full send. Keep at it, bro.

@zen1647 2 года назад

Bloody amazing video. Loved it!

@becomealex 2 года назад

I'm barely one-third of the way to the video and this is the best video I Feel you've ever produced! I'm loving the whole science aspect of this and I'm really looking forward to the science lab! Congratulations on all your success! Continue being excellent and may the Everlasting Computer Gods be with you through all your endeavors!

@jordanm2984 2 года назад

As a biology undergraduate and a PC enthusiast, this is one of the coolest videos you guys have released!

@Aepus 2 года назад

That pipette technique tho

@TechDove 2 года назад

My PC glowed once too, when my power supply shorted and caught on fire. Much cooler looking than this, but far more dangerous and expensive 1/10 do not recommend

@johanesrafael9679 2 года назад

Wow, power supply AND arc welding machine in 1 package! Now that's the deal of the year 😂

@TechDove 2 года назад

@@johanesrafael9679 hell yeah! I got so much done that the fire department came to congratulate me

@karine3126 2 года назад

AISURU.TOKYO/mizumi/?[🤤] (◍•ᴗ•◍)✧*。18 year and over RU-vid: This is fime Someone: Says "heck" RU-vid: Be gone #однако #я #люблю #таких #рыбаков #Интересно #забавно #девушка #смешная #垃圾

@karine3126 2 года назад

@Telhias 2 года назад

My PC glowed too! There was a fault in the power supply and it sent so much current to my graphics card, that it melted glowing red hot. Don't cheap out on power supply guys. The money saved on it was not worth that GPU.

@SkySweetie 2 года назад

Thank you for including how we can have fun and maintain the ground we stand on! Appreciate the full perspectives on reusable tech and safe tech.

@burkfivesix 2 года назад

Loved this science focused video and how you applied the science to your own application.

@balintmajor5416 2 года назад

Linus speaks like he knows what is he speaking about, he is a very good actor.

@Emma_madison 2 года назад

Well it all about putting up a show

@floofthefops 2 года назад

Am I the only one that absolutely loves when Linus goes to explore what other companies are doing? These videos are always very cool and usually talk about stuff I would never hear about otherwise. The episode about quantum computing was absolutely fascinating to me.

@MarcusBS 2 года назад

thank you for this! its fun to learn, and i want a ocean computer with some thing like this!

@shriramvenu 10 месяцев назад

this was a really entertaining and educational video. keep it up guys!

@Slinder14 2 года назад

We did a bioluminescence experiment in my bio lab a few years ago. To me it’s one of the coolest things in nature, and bringing it to a pc is amazing. Awesome video

@doggoonus1414 2 года назад

cool r6 clip ---> ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-H-BuXc18fQI.html

@luxbio 2 года назад

we so agree. what kind of experiment did you use bioluminescence for?

@DamnCyrus 2 года назад

That shot of the reservoir lighting up was so fucking good, hope those people get the work done to make the bio-luminescence usable in the future

@kwerboom 2 года назад

Cool and informative video. This is interesting technology. The in depth explanation of the science behind the technology was informative and appreciated.

@chrisashih5142 2 года назад

Great explanation of bioreactors! I think the balance of detail and hand-waving is perfect for a wide range of audiences for the given time constraint. This type of stuff is what got me into molecular biology in the first place, and I hope that anyone who finds inconsistencies is tempted to go find out the fuller explanation for themselves!

@mohidwaseem7997 2 года назад

Its amazing when professionals from two different walks come together to do something fun.... Like linus us so excited during the chemistry part and the people there are all serious and want to get it to work, then as soon as the PC comes in Linus goes serious 'lets let it run for the air bubbles' mode and the team there is all excited. Just a wholesome and lovely collab

@muhammadanwaril6872 2 года назад

keep it coming, Linus. environment-friend techs, repairable techs, things will eventually get better. hopefully.

@eisenklad 2 года назад

Linus should get Solar and possibly Wind power on his home

@TilmanBaumann 2 года назад

That's the quality computer content I can't here for nice work

@dontaskiwasbored2008 2 года назад

This is wildly out of scope for this channel and I love it.

@jackgotgamez 2 года назад

I bet with a lot of those “glow sticks” and the luminescence you could actually make yourself a diy glow in the dark lightsaber from Star Wars.

@oMega-sm1eg 2 года назад

Then it will be pretty heavy since it's filled with water, and not retractable of course. Now some excellent-looking lightsabers already exist using diffusion of a beam of LED light to light up the entire retractable blade.

@nickthemage2052 2 года назад

I feel like LEDs, a toggle switch, and a sanded plastic tube (to make it opaque) would be lighter and far cheaper lol

@oMega-sm1eg 2 года назад

@@nickthemage2052 Yes, that's what cheap sabers are, a LED strip in the middle and plastic outside. It's not retractable though, thus not a true lightsaber but a fluorescent lamp with color, attached to a handle

@nickthemage2052 2 года назад

@@oMega-sm1eg yes I’m aware.

@kelvinnkat 2 года назад

"I will not be making any unscheduled visits to the bathroom" Does that mean that he schedules his bathroom visits in advance?

@CallanElliott 2 года назад

You'd generally want to take your toilet breaks before a shoot, I'd reckon.

@kelvinnkat 2 года назад

@@CallanElliott Timing something is different from scheduling it.

@ahmozevi 2 года назад

What a wonderful idea also one part of pc water cooling system looked like the T Virus vial from resident evil and that sir was a very nice touch.

@TobiasLeonHaecker 2 года назад

I really like this (new?) Approach to give sustainable ideas ab big shout out in this big platform. Same with framework. Please more content like this.