The Thaw Parasite Explored | How the Immune System Tries and Fails to Clear Parasite infections 

Thanks for watching guys! I hope everyone enjoys the video and I will see yall next year! ;) Also new video up on Roanoke Tales! Let me know what you think broham ru-vid.com/video/%D0%B2%D0%B8%D0%B4%D0%B5%D0%BE-nHNRFlwsGSY.html&ab_channel=RoanokeTales

“Yelling at people to stay with you DOES NOT help.” Are you trying to tell me shitty hospital drama shows have lied to me?!

Of course NOW my body wants to do the "let's itch everywhere at once"- sensation

A BUG CRAWLED ON ME WHILE I WAS WATCHING THIS AND I *S C R E A M E D*

The bigger the parasite, the harder it is for the immune system to fight. However, the bigger the parasite, the easier it is for us to fight it!

If you ever see anyone pass out from alcohol consumption, also important to lay them on their side 👌👌

I thought this is a dark theory on the ice age animated movies

As an epileptic that has almost choked to death by being left on my back during a seizure, thank you for educating people about what to do when someone’s choking on their vomit. I was yelling at my tv watching that scene.

"we need to put Jane's body in further quarantine to save everybody." *Proceeds to break quarantine unprotected touches and closely examines her body more than possibly getting infested in the process before dragging her body dangerously close to herself into the sealed room with patient zero then closely examining patient zero's fur with her bare hands becoming further infected* Yeah, very smart

Movie: they’re not bugs. They’re vertebrates that look like bugs Me: *bangs head on a table*

earth is getting hotter r34 artists: GOD DAMN SHE IS

Well looks like the hazmat suit is never coming off and the flame thrower stays loaded

"Stay With Me!" Person: *Proceeds to gag and choke on vomit* "Stay With Me!!!" Person: *Literally Suffocating on puke* "STAY WITH MEEEE!!!!" Person: *Ded*

"I have a new phobia part 2, electric boogaloo" That's a big oof

This one here is a certified *Hans, get ze flammenwerfer* moment

Ok but there was an X files episode with this exact plot line. It won them an Emmy. Its like the producers of this movie watched that episode and said "nah no one will notice"

I had small maggots developing in a scratch on my big toe during a trip in the Minas Gerais in Brazil. I had to cut and cauterize. However, insect parasites need air to survive, and that's also true for their larvae. By staying immediately under the skin, these larvas are not too bothered by the immune system. Plus, they get oxygen through a small opening. The idea of having insects swimming into the blood flow is not too far fetched though. In nature, water contains 4 to 12 mg/L oxygen. Human blood contains even more dissolved oxygen, 15 mg/L. So in theory, an aquatic insect would be able to survive in human blood, but the insect would need to evade the immune system, which is geared against parasites. A big issue in this movie is that the insects reproduce way too fast. It's the case in most horror movies. Viruses make people sick in seconds. Insects and small animals lay eggs which become adult in a matter of minutes. In real life, the fastest thing is bacterial infection. A bacteria can start making you sick immediately after it gets into the body, due to toxins it produces. Anything else takes more time.

Horror movie central: "Hmm, we need to create something horrible that cannot be killed and is a swarm. Thoughts?" "Bug like creatures from the ice age that can kill everything and has no weakness and ignores the natural laws of life!" "Give them a spine and you're hired!"

Small point to make: ringworm isn't a worm at all. It's a fungal infection, not a parasite. I'll just assume you meant roundworms, instead.

It really gave me some serious anxiety when people didn’t use gloves and masks when dealing with dead animals and people in this movie. And any movie

"2021 will be the year of the electric car" rare Roanoke L?

Movie: they’re not bugs: They’re vertebrates that look like bugs evryone: you know that sounds like a bug

I want humans to know the error of their ways, so I'll do something that humanity will never know was their own fault. Good job dude

Y'know, as someone with a Parasite phobia, this was a horrible idea to watch. Your videos are amazing! And i am haunted.

Movie: *starts* That one scared dude: Pew pew pew!

It could only be brought back if we wanted to bring it back. *Umbrella Corp wants to know your location*

6-legged vertebrates with typical insectoid body segmantation. Sure, movie, sure...

Water bears survive for absurd amounts of time even in a hard vacuum.

The fact that they burrow in your flesh and lay eggs is already disturbing enough. But the fact that they’re also vertebrates somehow makes it even more disturbing.

By the logic of the movie: The main guy who wanted to release this to the world to force the world into caring about the environment would only end up forcing humanity into a completely enclosed artificial ecosystem and destroy all other life on the planet to survive.

Not a very deep grave, especially for an area that has wandering polar bears.

Yeah, this is definitely something I’d love to watch at 4:00 A.M. in the morning

Something to remember too, extremophiles like those discovered in melting permafrost are very specifically adapted to certain environments. So they can't just flip a switch and suddenly change. But that doesn't they can't hurt us, just not on movie levels. Though causing localized crop failures, mass die offs of livestock or death due to anaphylactic shock is possible. Meaning millions of humans and animals wouldn't die, but incidents causing hundreds of billions of dollars in damage, oh yes.

This movie just confirms my belief even more that it only takes one idiot to bring about the fall of humanity and probably everything else with us.

Kinda funny, fire seems to be their goto answer to everything EXCEPT stopping the guy bleeding... Cauterize that stump man damn

Botfly larvae burrow into human skin and so do Guinea worms so we already got skin crawling parasites. Nature can sometimes be more terrifying and cruel than our imagination.

It’s interesting to know, when you study immunology, that the human immune system is both efficient and inefficient at the same time; mindless cells that has a singular prerogative that might end up killing you rather than helping yoh

Imagine meeting a kid named crafting table or wooden slab

You should do a video on the parasites from the Back4Blood universe when the game comes out.

I'm watching this and screaming at them "Don't touch it with your bare hands!" Have these people never heard of gloves?

when that woman was dying from vomit I was literally yelling "turn her over!" what kind of self respecting college student don't know drinking 101?

Parasites benefit from their hosts surviving and even thriving in most cases, any parasite needs a viable host, its not usually in their best interest to just kill the host after one use. That's why intestinal parasites are so good at not being killed by us, because they usually don't harm us too much.

"Wow, good thing this movie doesn't happen in real life!" "Scientists in Canada have discovered a frozen caribou with a strain of Anthrax that we've never encountered before" ....

I feel like this is one of those movies that now belongs in the category of ‘yeah humans are that stupid’ after a year of covid

Thank you for doing a breakdown on this I haven’t been able to find much of anything about this on here

Some say they are cold as ice...willing to sacrifice...but that's only a legend

2:20 I can't believe you would say that I am literally crying and shaking right now. Literally

For a long time this movie freaked me out and set off my trypophobia. It was nice to see your take on it.

This page is giving me lots of knowledge and paranoia..

Them being vertebrates is just the tip of the iceberg. They have six pairs of limbs, the cephalothorax and abdomen distinctive of spiders and the mandibles of ants, and that's just the sketch of the male. The female looks like it has three series of multiple eyes as opposed to the male's two eye sockets, it's probably easier to fit in dragons to real biology than this thing.

I remember waking up to this movie after leaving the tv on. Was pretty decent. I would definitely like to see you look at the virus from “Blood Glacier.” Movie creatures felt like a a nice mix of Alien and The Thing elements.

God I ABSOLUTELY HATE body horror, especially the invasive, parasitic kind. Makes me itch.......and yet I still love watching your vids. I'm sure a psychologist would have a term for that......"hypocrite" probably. But your scientific analysis of these movies have always fascinated me.

RU-vid really doesn't like your channel right now. I have been watching you videos all day, am subscribed, have notifications turned on, and still your videos haven't once been on autoplay. Even if i went to your channel to pick the video it wasn't even a guarantee that you would be in the first scroll of recommended or that little bar of videos that shows up if you are watching in full-screen.

Hell yeah man, keep up the good work. You've been killing it lately 👊👊👊

"Some people wanna just watch the world....THAW" dad pun lvl over 9000

Love rewatching my favorite biology horror channel :)

Geez Roanoke, wish you coulda put a 'don't eat enchiladas' warning in the intro! Great video!

Back when this movie came out, I thought the behavior of the characters involved was pretty stupid, but looking at it now...

Film Makers: Yeah lets make all those science deniers really think about global warming! I fucking love science! Biologist: okay, but a bug wouldn't be able to survive 20k years frozen in ice Film Makers: So what you're saying is we should make them vertabrates?

I am very pleased you mentioned yelling look at me does not help. Why that's what happens in every single movie with such a scene in it is beyond me. Thanks for the videos duder.

Your humor is my humor!!! All the little jokes are just making it more and more enjoyable here!

Would you ever be interested in covering "the bay"? It has an interesting approach to a specific parasite seen in fish and I always wonder if the movies premise was even possible.

Roanoke: she is asphyxiating on her own vomit Me: ROLL HER ON HER SIDE OMG Roanoke: imma teach y'all--roll her on her side

Lord only knows why I’ve been ignoring you’re videos for so long They’re all so informative

"Help me I'm struggling to breathe" "StAy WiTH mE"

Friendly heads up: DON’T eat while watching this.

The magical cure for every invasion: Ketoacidosis... because Xenomorphes don’t play

Love your Count Dankula references!

I learned something new about saving someone. Thank you, roanoke

Basically in this movie....everyone is a idiot. Literally everyone. The main point of this being letting the emotionally unstable person who has shot the rifle repeatedly, taking out the radio, shooting the ceiling and his gf in the face, keep the gun

I remember seeing this when I was in highschool. It reminiscent of Cabin Fever. Throughout the film they all slowly but surely get infected, get worse over time and yeah there's some not so great cgi but story wise along with the pacing of the film makes sense. Not a blockbuster by any means but it wasn't terrible.

That moment when you’ve been watching so many Roanoke videos you get ads for immune supplements

I know this may not be up your alley in terms of interest, but I would love it if you'd cover some of the more 'out there' plagues from Plague Inc, like the Neurax Worm, Necroa Virus, and Shadow Plague.

This was the worst time to see this, while I am in a hyper sensitive state and even the wind feels like something is crawling on me ....

After watching so much Internet Historian it’s refreshing to see a normal Nord VPN add. Also, a bear eating a frozen mammoth kind of blows my mind. I mean, it’s not surprising at all that a carnivore/scavenger would happily eat something frozen, but that it doesn’t realize just how old it’s meal actually is is kind of weird to me. If a human discovered the mammoth they’d probably be like “holy shit! I need to tell someone about this! Who knows what we could learn by studying this ancient body!” But the best and crow just think “hongry,” I think I worded this really weirdly, but I hope you guys know what I mean.

At 9:50 “As she inspects the polar bear” - with her bare hands (pun unintentional) despite seeing all these clearly infected things, zero PPE despite STANDING IN THE LAB *insert SpongeBob rage gif*

“It was a real interesting day, the sun rose and set.” -Bilbo Baggins

"I don't wanna be here" *proceeds to get in the helicopter"

This reminds me of an archaeology student doing a dig in Alaska a few years ago at a hunting ground. He actually contracted a bacteria of some sort that was killing off his flesh around his knee which was the infection point. The dig called a hospital he was coptered out and some heavy antibiotics he’s alive and well today.

One reason why the parasite didn't eat the world back in the ice age could be because it was too successful. If it kills the host and its entire pack/herd out in the middle of nowhere then it's game over.

I really want to see this guy and high boi try to explain a movie together but keep getting in the way of each other.

I always thought this movie was a love child between "the thing" and "cabin fever"

Oh, hey. The bell notifications actually work, for once. Guess it doesn't have cold feet, anymore.

Watching this in 2023 still not the year of the Electric Car...

“2021 is gonna be the year of the Electric Car” *laughs in COVID*

This dude wanted to unleash a parasite to force climate change to get fixed- by unleashing said parasite to infect people *and animals everywhere* resulting in a total collapse and shift in global biomass???? Someone introduce this chap to the villain mum from the godzilla sequel lol

Looks like renal failure to me(though I'm wrong and have been corrected). For Jayne and Ling in their last vomiting sessions. I.e. if can't come out through the out pipe, it'll come out the in pipe instead. Possibly the parasites have actually spread into the abdominal cavity and caused a bowl obstruction. Pretty gnarly stuff and is also a potential symptom of roundworm.

Haha don't even remember hearing about this movie but stumbled on your vid here when trying to find another to watch.

Ah, yes an ant just HAD TO CRAWL ON ME WHILE WATCHING THIS

Atom's parent's might have been DC fans. At least they didn't call him Raymond.

If it was limited to mammals, I can see them being able to spin the "it was so deadly it killed everything before it could spread" card and make it semibelievable, but that ignores that a parasite takes much much much much longer to evolve than a strain of bacteria or virus. All in all, an interesting video and that definitely sounds like a horrific flic. Thanks for the vid! :)

Frog- “yeah I’m pretty evolutionarily advanced, I can survive up to 7 months in a low energy state of hibernation.” Tardigrade- “those are rookie numbers”

"2021 is gonna be the year of the electric car, mark my my words" oh you sweet, sweet, innocent boy.

This man is the most likely to survive a zombie apocalypse I swear

"How unlikely it is theyll survive thay deep freeze" oh the foreshadowing 😂

Seeing this is pure suffering because I have a phobia of parasites and insects

"Could this really happen" Any other year i would say no.....any other years

On a hopeful note, if the parasite is that virulent yet still localized to one mammoth, maybe the reason it didn’t kill all life on earth was a microbial predator. Perhaps the parasite is highly succeptable to a particular virus or common bacterium that most animals had a symbiosis with.

9:16 now I have a new phobia part 2 the electric boogaloo

Where's my ELECTRIC CAR BRUCE!!!