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Understanding Diabetes Insipidus 

Zero To Finals
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This video contains a detailed and simplified explanation about diabetes insipidus. We discuss the differences between cranial and nephrogenic diabetes insipidus, the signs and symptoms, testing for diabetes insipidus including an explanation of urine and blood osmolality and the water deprivation test (also known as the desmopressin stimulation test) and how we manage diabetes insipidus.
More written notes and diagrams about diabetes insipidus are available on the website at www.zerotofinals.com/diabetesinsipidus
Zero to Finals Medicine book:
UK: www.amazon.co.uk/dp/1091859892
US: www.amazon.com/dp/1091859892
Zero to Finals Paediatrics book:
UK: www.amazon.co.uk/dp/1080142827
US: www.amazon.com/dp/1080142827
Zero to Finals Obstetrics and Gynaecology book:
UK: www.amazon.co.uk/dp/B08K4K2WQB
US: www.amazon.com/dp/B08K4K2WQB
Website: www.zerotofinals.com
Notes: www.zerotofinals.com/learn
Multiple Choice Questions: www.zerotofinals.com/test
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DISCLAIMER: This video is for education and entertainment only, and is not medical advice. This video should NOT be used for medical advice or to guide clinical practice. The Zero to Finals content should not be used in any way to guide medical decision making. Zero to Finals takes no responsibility for any actions taken or not taken based on the information provided. Local and national guidelines and senior clinicians are there to help you make decisions, not RU-vid videos. If you need medical advice or information, seek it from an appropriately trained and licenced doctor or healthcare provider that can address your individual needs. Zero to Finals cannot guarantee the accuracy of information in this video. Please highlight any errors you notice in the comments below - thank you.

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2 июл 2024

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Комментарии : 441   
@MysticiaDevHoopsMacabre
@MysticiaDevHoopsMacabre 2 года назад
This really was helpful, man. Thank you. I have Cranial DI. Five years ago in November of 2017, I started drinking lots of water after I was diagnosed with Brain Cancer. Now I know for a fact that, yes, the tumor did effect my Hypothalamus in my brain and that’s what I causing Cranial DI. I have had a Fluid Deprivation Test recently and I’ve been given a prescription for Desmopressin. Tomorrow I start taking it. Wish me good health and good luck!
@koolforkatss9155
@koolforkatss9155 2 года назад
I was diagnosed with central DI in 2017 too, desmopressin has reverted me back to normal. Hope it works for you too!
@simplynouna896
@simplynouna896 2 года назад
ربي يشفيك ويحفظ صحتك 🙏
@jonathanmendoza748
@jonathanmendoza748 2 года назад
Yeah had since I had a brain tumor, it’s annoying
@ellenlee1
@ellenlee1 2 года назад
WHEN YOU TAKE THE DESMOPREEIN IT MAKES YOU RETAIN FLUID IF YOU DRINK TOO MUCH, AND THE DDVAP KEEPS THAT FLUID. WHEN I EASE UP AND TAKE LESS DDVAP I URINATE SO MUCH. I CAN'T KEEP A BALANCE. WITH THE DOSAGE AND FLUID INTAKE.
@Jcccc23
@Jcccc23 2 года назад
Hey bro was your urine clear during the water deprivation test ?
@harjii
@harjii 4 года назад
This was incredibly helpful! You broke the condition down into bite sized chunks and explained it in a way that was easy to understand and digest. Thank you so much!
@ZeroToFinals
@ZeroToFinals 4 года назад
glad to help
@noonessam4281
@noonessam4281 Год назад
This chanel is God sent for struggling Med students. Thank you so much.
@jasmined9752
@jasmined9752 3 года назад
This has been so good to watch! I was diagnosed with diabetes insipudus after a brain tumour at aged 9 . I feel like there us so little known about it. Often when I take desmoprssin along with various other medication people will ask "what's that for?" and if I just reply with diabetes they will often jump to the conclusion that I have type 1 or 2 diabetes. It's videos like this that start to bring about a bit more awareness to help get people diagnosed quicker and bring about understanding
@christophergalvan7215
@christophergalvan7215 3 года назад
Same things happen to me insta :@sunsh1ne.2
@illegaldru6s5
@illegaldru6s5 3 года назад
@@christophergalvan7215 heyy man I've been going though hell trying to figure out why I've been drinking and peeing so much headaches my legs hurt . I think I might have this . I followed her on Instagram my name is irljit on there did u have similar symptoms
@jay-if8qs
@jay-if8qs 3 года назад
yea me too it took years and a whole new state to be able to figure out what was going on
@illegaldru6s5
@illegaldru6s5 3 года назад
@@jay-if8qs yoo jomar wassup with you bro can we talk
@illegaldru6s5
@illegaldru6s5 3 года назад
@@jay-if8qs I've been going through hell homie
@23jparra
@23jparra 4 года назад
I had cancer when i was 13. I had a tumor on my pituitary gland. So the gland doesnt work. I got diabetes insipidus among other things. I want to study it and understand it thank you for the video
@weazle5255
@weazle5255 4 года назад
Similar I'm 26 I got diagnosed with a pituitary tumor and now have a nice 64oz thermos of ice water all the time
@user-uq5tj9ty6s
@user-uq5tj9ty6s 4 года назад
Andrew Sherwood hey, do u have problem with polyuria?
@T_oasty
@T_oasty 4 года назад
I have a benign tumor called craniopharyngioma. Is that possibly what you have? Mine surrounded around my pituitary gland and completely disintegrated it. I have to take medications not only for my hormone replacements, but also because of my diabetes insipidus. I'm sending sending prayers your way! 🙏
@weazle5255
@weazle5255 4 года назад
@@user-uq5tj9ty6s yes I know it as diabetes insipidus I drink a Lot of water and have to pee frequently. I take desmopressin at night so I dont keep waking up to go.
@weazle5255
@weazle5255 4 года назад
@@T_oasty I had a benign tumor on my pituitary gland it was a germinoma I had to have blood brain barrier chemo and radiation. But I'm doing good now
@jasondoyle1037
@jasondoyle1037 2 года назад
Thank you for such a lucid explanation of the condition.
@carrieberrykix
@carrieberrykix 2 года назад
We're testing our dog for DI right now testing with desmopressin. This really helped me understand what the vet was talking about!
@acidburstman
@acidburstman 2 года назад
Very helpful. The water deprivation test was confusing in my book. Here it was easy to understand.
@amandasarahi
@amandasarahi 3 месяца назад
I came upon this series and didn't realize I had already subscribed. So far the best simple explanation and I retain the information! Thank you!!!! -nursing student approved!
@perkyiff9226
@perkyiff9226 4 года назад
came here for a quick recap back on the topic from my psychiatry revision after encountering DI as one of the side effect of lithium. thank you for the short and sweet explanation!
@ZeroToFinals
@ZeroToFinals 4 года назад
Glad to help!
@shreyasharma9978
@shreyasharma9978 3 года назад
You are a very good teacher, who makes things easier. Thank you. Keep creating videos😊
@winniefindstheway
@winniefindstheway 16 дней назад
Agreed and his voice is pleasant for taking in the information too 😅 that helps me... I can't tell you how many vids I click off because I can't stand the taking in the info because the voice is rough to my ears ( I'm AuDHD and very sensory sensitive)
@user-fi5mn8gv4z
@user-fi5mn8gv4z 4 года назад
Simple , concise and informative . Thanks
@magchisholm3931
@magchisholm3931 Год назад
Helpful, I love that ur voice is calm. Thanks for illustration and clarity of notes💓
@gaurisd10
@gaurisd10 5 лет назад
Very helpful, and the site is really resourceful. Thank for the site too.
@putaschimi2185
@putaschimi2185 3 года назад
Cheers for the Video! Forgive me for chiming in, I would appreciate your opinion. Have you heard the talk about - Patlarny Sweet Days Principle (just google it)? It is a good exclusive guide for getting rid of diabetes minus the hard work. Ive heard some extraordinary things about it and my friend Sam after a lifetime of fighting got amazing results with it.
@mdawaisilyas
@mdawaisilyas 2 года назад
thank you so much very simplified explanation! highly appreciate your work!
@emanalharthi7240
@emanalharthi7240 3 года назад
Easy,simple and very clear!!! Thank you
@tommy-tp3hj
@tommy-tp3hj 2 года назад
Very clear, explanatory, and helped me reviving some knowledge for my exam, definitely going to subscribe.
@yourlocalfairyhere
@yourlocalfairyhere 4 года назад
I have the cranial type of diabetes insipidus and I am on medication! What really triggered me to know more about this disease is that I actually have a pesenstion about diabetes mellitus in a few days and while preparing for it I realized, it really does not have anything to do with this type of diabetes and that I actually wanted to know more. Thank you for this video!!!!!
@user-uq5tj9ty6s
@user-uq5tj9ty6s 4 года назад
패리대Feride how long time u used desmopressin?
@yourlocalfairyhere
@yourlocalfairyhere Год назад
@@user-uq5tj9ty6s oh sorry I am seeing this comment only now 😅 but if you still want to know I have been using it since 2017! Sometimes I have to use it every 18 hours but sometimes every 12 it really depends I have good and bad days
@nijabudeenmohammedn5354
@nijabudeenmohammedn5354 10 месяцев назад
​@@yourlocalfairyherestill u are using or stop .how di caused you
@yourlocalfairyhere
@yourlocalfairyhere 9 месяцев назад
still using it@@nijabudeenmohammedn5354
@adesodivine1403
@adesodivine1403 3 года назад
So grateful for the update. I am a masters students in Public health and this was worth the study
@Tara-dd3qn
@Tara-dd3qn 3 года назад
thank you so much I am a senior nursing student and found this very helpful
@makhseed
@makhseed 3 года назад
this video is amazing! thanks for the upload!
@stacyuz1704
@stacyuz1704 3 года назад
Thank you! Thank you! Thank you!!!🥺🥺 this helped tremendously.
@JJJResearch
@JJJResearch 11 месяцев назад
simple but concise explanation.... Really helpful to understand the concept.
@firasbourghol574
@firasbourghol574 2 года назад
excellent and covers all the causes! thank you
@gabrielarodriguez6191
@gabrielarodriguez6191 2 года назад
Thank you so much! Perfect explanation! You helped a lot!
@ankitkawale9748
@ankitkawale9748 4 года назад
Very well explained. Thank you
@IslandgirlintheMedWorld
@IslandgirlintheMedWorld 4 года назад
You are heaven sent!! Thank you!!!!
@ZeroToFinals
@ZeroToFinals 4 года назад
so glad to help
@lanavoliladygagu
@lanavoliladygagu 4 года назад
thank you, great explained
@dinosaurxxxx
@dinosaurxxxx 3 года назад
I had given up hope as to why I have to urinate very excessively, but now I have hope after finding out about this, going to mention it to my doctor and ask for testing! thank you!
@pocheslol2280
@pocheslol2280 2 года назад
U might just be diabetic but what happened
@rockenrob4893
@rockenrob4893 2 года назад
The testing is rough. I was deprived of all liquids for 16 hours and in the hospital for 4 days
@freedaboyoung3722
@freedaboyoung3722 Год назад
@@rockenrob4893 well shit, that is the test 8 and 8 hrs. But it didn't seem as daunting during the video. Now that you mentioned it, you had to fast a whole 16 hrs!
@freedaboyoung3722
@freedaboyoung3722 Год назад
@@rockenrob4893 how were you given desmopressin? Tablets form with water? Or nasal spray? And how much of it? I'm interested in knowing
@rockenrob4893
@rockenrob4893 Год назад
@@freedaboyoung3722 I had to stay in the hospital for 4 days. The doctors monitored me and wouldn’t let me drink for 16 hours. It’s a really awful experience but the rewards of the meds is worth it. You should go talk to an endocrinologist.
@ananyanethi4031
@ananyanethi4031 3 года назад
love this video. thank you so much
@fhaihatulakma3998
@fhaihatulakma3998 3 года назад
This video really helps me to understand for my presentation. Thank youuuuu!!!!!
@JixieDyeAuthor
@JixieDyeAuthor 3 года назад
If you need more help, I have had DI all my life. You probably already did your presentation. Hope it went well.
@elenamartinez2387
@elenamartinez2387 4 года назад
THANK YOU!!! This video is amazing!!
@ZeroToFinals
@ZeroToFinals 4 года назад
Glad you like it!
@ingridbernardes719
@ingridbernardes719 4 года назад
Oh my god, this video is amazing! Thanks for this!
@ZeroToFinals
@ZeroToFinals 4 года назад
You're welcome!
@alextufan6675
@alextufan6675 Год назад
Thanks for your video, it was very helpful!
@haileeroxana
@haileeroxana 2 года назад
Beautiful explanation thank you so much
@katierush9584
@katierush9584 2 года назад
I really appreciate this, well explained
@choc23able
@choc23able Месяц назад
Thank you. Very useful 'to the point' explanation
@hildamakule713
@hildamakule713 4 года назад
Very helpful. Thanks a lot.
@pradnyawaskar7843
@pradnyawaskar7843 3 года назад
You are doing just great job ! Very Helpful. Make more n more videos.
@nageenahsan8288
@nageenahsan8288 3 года назад
Loved it! Thankyousomuch ❤️
@ibtihalozturuk6017
@ibtihalozturuk6017 3 года назад
Thank u doctor it was a very good explication . good luck for all what u r doing
@medicalscience1528
@medicalscience1528 2 года назад
Hello, thanks for amazing lecture. Can you tell why you mentioned primary polydipsia as key diagnosis ? Does this habit or ritual leads to diabetes insipidus ??
@JHilariosaH1
@JHilariosaH1 Год назад
This helped my family members understand my insatiable need for water. My pituitary gland was removed along with a brain tumor when I was 3 years old.
@filmyhari9373
@filmyhari9373 10 месяцев назад
What is your age now? How are you doing? How many hormones you replace
@user-vi1ff8fk8l
@user-vi1ff8fk8l 2 года назад
I have given up all hope of living abroad after frustrating attempts to treat an excessive thirsty and urination condition. Tanken a lot of meds to treat my prostate, said to be contracting incorrectly and I was even told to do a surgical procedure that wouldn't allow me to have children. Then I changed doctor after doctor e one have told me to take desmopressin due to high level of urine/day (5L), it's been 3 week of 0,1mg and my life changed so much, I'm a new person. Lately I have been facing these problems again, but I've been drinking lots of water due to anxiety, though I feel much better now in my life. Don't let this ruin your life, take good care of yourself.
@kurtkeisel4423
@kurtkeisel4423 3 года назад
Thank you my dog has this. Very good explanation
@jairamireddy7048
@jairamireddy7048 2 года назад
Excellent talk
@modjadjibeautymaake7728
@modjadjibeautymaake7728 2 года назад
Super Helpful. Thank you so much!!!!
@douglasw1545
@douglasw1545 4 года назад
Very helpful thanks for the video
@deiaarahma8729
@deiaarahma8729 5 лет назад
Great description thank y Doctor
@ZeroToFinals
@ZeroToFinals 5 лет назад
No problem Deia!
@yolandaorozco7892
@yolandaorozco7892 2 года назад
Thank you that’s what my son is going through it’s really confusing and frustrated because I feel like the doctor Are not doing enough
@exploreethiopia3376
@exploreethiopia3376 7 дней назад
Thanks for your video.
@pipatsukcharoen2265
@pipatsukcharoen2265 2 года назад
Good summarize thanks!
@jenrferruso
@jenrferruso 2 года назад
THANK YOU!!! I WAS BORN WITH THIS 9/5/74 AND NOT DISCOVERED TIL 3/26/1996 AND NOW DISABLED FROM SEIZURE 10YRS TO THE WAY DISCOVED AND THE DRS GAVE ME MEDS AND 3MTHS IN HOSPITAL THANKFULLY GOT TO LIFE!!!! THAT GOD!!! PEACE BE WITH YOU!!!
@jenrferruso
@jenrferruso 2 года назад
......"guess i will get to the john! ")
@pratikshanoudiyal4276
@pratikshanoudiyal4276 4 года назад
Great explanation!!
@RyanS32
@RyanS32 5 лет назад
I was recently diagnosed with cranial DI due to radiotherapy 6 years ago. Thanks for helping to understand what exactly is happening to me.
@mariettmariett292
@mariettmariett292 5 лет назад
Ryan Hi! How do you cure it?
@RyanS32
@RyanS32 5 лет назад
@@mariettmariett292 I'm not sure there is a cure. My endocrinologist has me on desmopressin to relieve the symptoms, but he hasn't mentioned anything about a cure to me.
@kostabeqir7373
@kostabeqir7373 4 года назад
HDX SNKWOQKSKJ,K🐅❤🐯😭💪🏿💪👍😺😸😸HNSJDJCISFUWJDJFJZXKSKMNC DNJCNCNCNDNWI1OQODJFJCIF HNSNJENFJDJKEKDDHDJCLCKNDLDL JDDJKFJCKFKCC DJFJCJNDJCCNCNNCM DJJFJ JDJFKCNCMX JDJCNE DNCMMCMCEM DMCMCMJFKF KDKFJCNC DJJFKC JDJJCNCKC FJJCJCJCJCJDJFJDIU33IDJC DMKMCKFKK
@JixieDyeAuthor
@JixieDyeAuthor 3 года назад
I was born with cranial DI. if you wanna talk I am here! I am so sorry that you had to go through radiotherapy.
@gunjanprithiani4799
@gunjanprithiani4799 2 года назад
Thank you so much!!!
@sabbyeight
@sabbyeight Год назад
Praying God’s help and healing for everyone impacted by DI. May God’s compassion shine on you and your family members. Stay hopeful. I too ❤
@alexismarquess9274
@alexismarquess9274 3 года назад
Amazing thank you!
@thacompilations4010
@thacompilations4010 Год назад
I love your videos. Thanks
@daigb749
@daigb749 4 года назад
Thank you 😍
@deepwithin6517
@deepwithin6517 2 года назад
Thank you very helpful.
@verysnowy4605
@verysnowy4605 Год назад
That helped me understand DI which I think I may have. thank you.
@snehajadav7701
@snehajadav7701 2 года назад
Thank you so much 😊🙏
@fatma8711
@fatma8711 4 года назад
Thanks alot it’s very useful
@arushiaishwarya8907
@arushiaishwarya8907 5 лет назад
This was so helpful. Thank you.
@ZeroToFinals
@ZeroToFinals 5 лет назад
Glad you liked it Arushi
@faresz7575
@faresz7575 4 года назад
HAIKI DIARETES REMEYDY Joni one of the highest converthing highest EPC blood sugar & Diabetes offers it is blood suggar control diet👌👌 1.proven Product with real results 2. High customer satisfaction tinyurl.com/yb7h7rae
@aween42
@aween42 2 года назад
Thank you sir, this was great
@ariciagomesmiranda2782
@ariciagomesmiranda2782 Год назад
Fantastic video!
@Peter-re6in
@Peter-re6in 2 года назад
Great explanation
@srimapradhan9174
@srimapradhan9174 4 года назад
Thanks u made it really easy
@ZeroToFinals
@ZeroToFinals 4 года назад
I'm so glad you liked it, thanks Srima!
@jaredfernandez2982
@jaredfernandez2982 4 года назад
Great video and overview of the pathophysiology of diabetes insipidus! One critique, the arrow that is shown @ <a href="#" class="seekto" data-time="164">2:44</a> of the video is vaguely misleading. It implies that ADH is released/produced by the anterior portion of the pituitary gland which is incorrect. The posterior pituitary gland releases ADH. Thank you for making such great work and I'm glad to see these concise and helpful videos. Thanks again!
@ZeroToFinals
@ZeroToFinals 4 года назад
Good point. Hopefully this doesn't mislead anyone. Thanks!
@creatineanhydride2314
@creatineanhydride2314 2 года назад
I thought the same too
@zj9338
@zj9338 3 года назад
very helpful thank you
@annamarianalumansi3178
@annamarianalumansi3178 2 года назад
thank you
@hwandre
@hwandre 2 года назад
CDI since 3 as well, been over 40 years with it now. Got it from a very high fever at that young age for a long period of time. I think I'll do a RU-vid on how this eventually also turned to Type 2 for me because of my ignorance about diet soda.
@nijabudeenmohammedn5354
@nijabudeenmohammedn5354 10 месяцев назад
Currently I am 21 ,last year oct 10 onwards I got high fever then after two or 3 weeks cdi caused me .There is no specific reason in the case of me to cause other than high fever
@nijabudeenmohammedn5354
@nijabudeenmohammedn5354 10 месяцев назад
Is it hereditary did you have children
@lwestern285
@lwestern285 5 лет назад
Good stuff thanks for explaining so clearly! I believe Thiazide diuretics can also be used for nephrogenic DI
@ellenlee1
@ellenlee1 4 года назад
YES, hctz is a diuretic. i think it makes the body put out ADH. when I forget to take hctz ( i take it for high blood pressure for 50 years) I urinate constantly. I think you are right. do doctors know this?
@wahajmayar6558
@wahajmayar6558 2 года назад
Really, I searched much more about this fact, but I couldn't find it that by which mechanism does it work?
@Hasnathalip
@Hasnathalip 2 года назад
Thank You Sir ✨️
@malakrfd8236
@malakrfd8236 2 года назад
Thank you so much, That was so helpfu!
@sakouraboukrif2380
@sakouraboukrif2380 4 года назад
Merci , très informatif
@emmanuel_nwogu_medic
@emmanuel_nwogu_medic 14 дней назад
Lovely video. What tools did you use in making this awesome video? How did you get the images you used, did you create them yourself?
@shahnasshajahan529
@shahnasshajahan529 7 месяцев назад
Thank you sir ❤
@asiimwekemigisha7240
@asiimwekemigisha7240 Год назад
This was really helpful
@majoodb9253
@majoodb9253 4 года назад
This is amazing,!!!!!
@ZeroToFinals
@ZeroToFinals 4 года назад
Glad you liked it Majood
@noornooralnager2649
@noornooralnager2649 5 лет назад
Thank you
@ZeroToFinals
@ZeroToFinals 5 лет назад
No problem. Glad it helped
@MuhammadAli-ml9bt
@MuhammadAli-ml9bt Год назад
THANKS ALOT
@srinivasaraosirasapalli5104
Excellent
@jayaraj6279
@jayaraj6279 3 года назад
excellent work 👏👏👍
@ashishpoudel840
@ashishpoudel840 3 года назад
Thanks
@merakichan8996
@merakichan8996 3 года назад
Man thanks very much it helped me very much so a lot of thankkkkksssss😊
@saidmo1797
@saidmo1797 Год назад
Thank u!
@MsPetiteasian
@MsPetiteasian 4 года назад
this is amazing!!!!
@mikeymouse4072
@mikeymouse4072 3 года назад
Elva Maria rivas is Scizophrenia and diabetic
@muthummm6675
@muthummm6675 2 года назад
Nice To See You. It is pleasure For Me To Comment Here!. Very Honest And Good!
@luissilame7909
@luissilame7909 3 года назад
Thanks for sharing! My sweet niece was diagnosticated this disorder ! She had histiocytose!
@pauldg913
@pauldg913 3 года назад
Is she diabetic?
@JixieDyeAuthor
@JixieDyeAuthor 3 года назад
I have diabetes insipidus too. I am in my thirties. She will be ok.
@pauldg913
@pauldg913 3 года назад
@@JixieDyeAuthor do u have medicine? And are u avoiding specific foods?
@AR_HUB663
@AR_HUB663 2 года назад
Hiii my daughtr 4 yr with histocytosis she also have this condition 😥😥
@cutiee225
@cutiee225 5 лет назад
Omg thank you!
@ZeroToFinals
@ZeroToFinals 5 лет назад
No problem. hope it helped
@muthummm6675
@muthummm6675 2 года назад
fantastic
@aakashnhoor185
@aakashnhoor185 4 года назад
Great video but i think the gold std is the Hypertonic Saline Copeptin Stimulation test not the water deprivation test might be wrong
@MudLover
@MudLover 2 года назад
Fantastic didactics
@mvpvals3966
@mvpvals3966 Год назад
thamks!!!
@ThatsWhy-
@ThatsWhy- Год назад
Great!
@wahajmayar6558
@wahajmayar6558 2 года назад
Is there anyone to explain the mechanism of HCTZ in the treatment of DI? I tried more but couldn't find!
@dasharenkeu2771
@dasharenkeu2771 4 года назад
Thanks for your help! I'm from Ukraine and I study English. I'm pharmacist and for I know this information in Ukrainian. But it really makes me study English well and I repeat the information for my job. You are great!
@ZeroToFinals
@ZeroToFinals 4 года назад
Glad to help!
@aaronmbwabi
@aaronmbwabi 3 года назад
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