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What is Kinesin? Ron Vale Explains 

UC San Francisco (UCSF)
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Ron Vale explains the inner workings of the motor protein called kinesin (“kin-EE-sin”) that transports vital components within cells and also separates chromosomes during cell division. He discovered kinesin when he was at Woods Hole, MA and continued his kinesin research at UCSF.

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26 июн 2024

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Комментарии : 138   
@byte2702
@byte2702 3 года назад
I learnt about motor proteins a few years ago. Until then, I thought biology is quite boring. I think it is absolutely fascinating and also cute that something so small exists in everyone’s body. It looks incredibly cute how they walk around on their legs.
@DP-ot6zf
@DP-ot6zf 3 года назад
It's like they're showing off some dance moves.
@unknown61320
@unknown61320 9 месяцев назад
theyre actually walking on their head
@WNYXeb777
@WNYXeb777 9 месяцев назад
I'm busting balls of the Scientific Naturalists who endeavor to support Darwinian non-sense. So I insinuated that the Kinesin machines were initially only bound by 1 " foot " for millennia while awaiting the 2nd extension to miraculously incarnate. Sorry for the confusion .... trolling's a bad habit of mine.
@chayito7
@chayito7 2 года назад
What a fantastic explanation. I took Bio-231 and we learned everything about proteins, kinesin, ATP, ADP, etc. It's fascinating to realize what goes on within our bodies.
@athanassiosdesigner
@athanassiosdesigner 3 года назад
Your Question and your dedication for an answer is inspiring and admirable.
@antoinekiwi2
@antoinekiwi2 4 года назад
Astonishing and actually awesome.
@davehibbs9111
@davehibbs9111 2 года назад
Keep up the great work you do! I'm very fascinated with the inner workings of the cells...
@carolgonzales1410
@carolgonzales1410 5 месяцев назад
Thank you! I never knew this was going on.
@Mindsi
@Mindsi Год назад
Still mechanistic @ the molecular level! Signature in the cell? Great book!
@westfield90
@westfield90 4 года назад
Just remarkable
@claaguilar586
@claaguilar586 5 лет назад
Having the one who discovered it tell about it :0
@youbigtubership
@youbigtubership 3 года назад
I hope this research rewards Dr Vale with a great life. Disciplined curiosity is what got science going in the first place. Now disciplined malevolence abuses scientific techniques to find ways to destroy or dominate others.
@muralidharan6755
@muralidharan6755 Год назад
Omg thanks ... Alot of years i wanted to know about motor protein and Kinesin protein walk animation. But not able to get correct explanation and details. Finally scientist who actually discovered this explains ❤️❤️❤️. I wanted to be a biotechnology engineer from my school and childhood days 🥺🥺🥺🥺🥺... But now I am a software developer. But still biology fascinates me
@dilekgokce1035
@dilekgokce1035 2 месяца назад
Sizi büyüleyen şey ne ise onu yapın🎉
@magellanaa
@magellanaa 3 года назад
incredible
@annabelleregnault9840
@annabelleregnault9840 3 года назад
Those cells be like :‘I’m walking like a model’
@Sadoda777
@Sadoda777 2 года назад
There are some really smart people in this world
@fallenneutron2740
@fallenneutron2740 22 дня назад
We need stronger and smaller cameras so we may see the action closer up
@adriansue8955
@adriansue8955 Год назад
How do they Synchronize? what keeps the two 'feet' of the kinesin from releasing at the same time and losing grip?
@erdemmemisyazici3950
@erdemmemisyazici3950 Год назад
It's so cute! 😄
@joshuabowman7210
@joshuabowman7210 2 месяца назад
Was the Dynien found the same time the Kinesin was found ?
@glenliesegang233
@glenliesegang233 9 месяцев назад
Ok. These are specified as base 4 digital information, as are the 6 different cargo linking proteins. Wish Dr Vale would tell us his thoughts on how...
@johnboyajian1689
@johnboyajian1689 Месяц назад
I have to call the ucsf billing department next week to see if I owe anything.
@franceniajohnson367
@franceniajohnson367 3 года назад
Awesome turning chemical energy into motion
@mrsamandabernier
@mrsamandabernier 3 года назад
Soooooo cool
@MarianoCiancone
@MarianoCiancone 11 месяцев назад
I wonder if they are run off opposing magnetic poles/fields
@errydm
@errydm 3 года назад
1:35 What do you mean kinesin carrying plastic bead? 😳
@Wizardmaster55
@Wizardmaster55 3 года назад
This was an experiment to see if Kinesin would carry something outside it's normal routine. Lol I had the same thought though, like "uhhhh, why is plastic in someone's body??" Lol
@errydm
@errydm 3 года назад
@@Wizardmaster55 Oic.. thanks for the clarification.
@mrsamandabernier
@mrsamandabernier 3 года назад
Literally I paused the video to read the comments to find out if I read that right 😂 glad I'm not the only person who said "Woah, wait... What?!" about the plastic bead lmao
@TheRoliX
@TheRoliX 4 месяца назад
This raises more questions than it answers. Great job, however we still know nothing.
@weltschmerzistofthaufig2440
@weltschmerzistofthaufig2440 2 месяца назад
What do you even mean by that?
@bahaamesbah538
@bahaamesbah538 3 года назад
What make the kinesin move towards plus end ??
@user-dt6sr8pq4t
@user-dt6sr8pq4t 2 года назад
The creator our god
@user-cv1dz4pi4u
@user-cv1dz4pi4u Год назад
Energy from ATP and attraction between protein molecules
@francescaoliviero892
@francescaoliviero892 3 года назад
is Kinsesin the only motor protein in nerurons?
@hariprabhu9725
@hariprabhu9725 3 года назад
Nope. Dyenins also
@emmabee5027
@emmabee5027 3 года назад
Three major families Kinesins, myosins, and dyneins can be found in neurons and in other types of cells
@khatharrmalkavian3306
@khatharrmalkavian3306 2 года назад
I feel like there should be a Hataraku Saibou spinoff that happens with proteins inside a human cell instead of cells inside a human body.
@kasuraga
@kasuraga 2 года назад
so instead of Cells at Work! we get the spin off Proteins at Work!
@01MeuCanal
@01MeuCanal 4 месяца назад
Pure Divine Engineering.
@geoffroyboulanger110
@geoffroyboulanger110 Год назад
Could that be adapted to remove microplastic from water?
@lawrence3710
@lawrence3710 4 года назад
Here from, "Still Lost I Guess, Here's a Tunnel""
@edwinubod0405
@edwinubod0405 Год назад
From Twitter
@personfromctc1300
@personfromctc1300 4 года назад
here from flemming
@naveensharma7478
@naveensharma7478 8 месяцев назад
😀😀😀😀👍👍👍👍👍👍
@annah2933
@annah2933 2 года назад
M.I.L.M.M Man I Love Molecular Motors
@stuffedcinema7374
@stuffedcinema7374 2 года назад
do you like monkeys?
@annah2933
@annah2933 2 года назад
@@stuffedcinema7374 I am addicted to monkeys. I would sacrifice my life for monkeys. I love literally everything about monkeys.
@CoolWhipGaming568
@CoolWhipGaming568 7 месяцев назад
He hitting that Crip walk
@saralyog1580
@saralyog1580 6 месяцев назад
I am use subtitle hindi
@RobWill5864
@RobWill5864 Год назад
As above so below
@WNYXeb777
@WNYXeb777 11 месяцев назад
Remember all Kinesins constitute a superfamily of ATP-driven microtubule motor enzymes that convert the chemical energy of ATP hydrolysis into mechanical work. They all hopped about on 1 foot for a million years until a mutation gave them a second leg.
@Cameroonian
@Cameroonian 10 месяцев назад
Do you have a source for that claim?
@WNYXeb777
@WNYXeb777 10 месяцев назад
Ummm -- Anti Naturalistic Darwinian Biological Evolutionary Sarcasm ??!!!!!@@Cameroonian
@Cameroonian
@Cameroonian 10 месяцев назад
@@WNYXeb777 Anti-Evolution? Yes. It's like saying if I jumble a few tools around long enough, I can get a Boeing Jet with instruction manual.
@WNYXeb777
@WNYXeb777 10 месяцев назад
I prefer the tornado tearing through the Texas sized junkyard and depositing a functional ( Car, jet, hell how about a working toaster ). Natural Science philosophy is a crock of **** . From geologic time scale and depositional sedimentation to Biology n Chemistry with Abiogenesis and Natural Selection all the through Cosmogony and cosmology everything they state is an epic failure of interpretation or a backwards manifestation of logic.@@Cameroonian ? How many Darwinists does it take to change a light bulb???? Answer --- None just wait long enough and it will change it self.
@satiremuch2643
@satiremuch2643 9 месяцев назад
Well, that's a ridiculously frivolous claim. This guy and his team discovered the thing in 1984, but here you come along and know the history of this protein, based on what evidence? Surely not archeological evidence. Why didn't anyone describe the origin story for kinesin before they knew of its existence. We just barely understand the mechanisms of this thing, as Mr Vale said, there are lots of unanswered questions and if you don't fully know the mekanisms of a process you can't give reliable explanations for its origins. But you can always show the opposite is true and describe some other structures and mechanisms that no one knows about and along with thier origin stories.
@kyokushin-
@kyokushin- 7 месяцев назад
Subhan Allah the Creator ❤ Thank you for spreading knowledge.
@ayoubchadli1
@ayoubchadli1 3 года назад
سبحان الله
@leowilliams9122
@leowilliams9122 Год назад
There is truly an intelligent Creator at work. God is unfathomable.
@thoughtthinker9300
@thoughtthinker9300 Год назад
All of this, no matter how complex, comes down to the very same BEGINNING QUESTION. If in deed we are too complex to be created by random chance happenings, and we were purposely created by design. HOW was the first being or whatever in this chain of life and creators created? BUT BY THE SAME CHANCE OF RANDOM HAPPENINGS, THAT ARE SAID IT'S IMPOSSIBLE TO DO. Or in short. Who and How was the first "????" that was created, CREATED? Or is that us? Or where and who or what "was it" ? This is and may always be the ultimate "BEGINNING QUESTION". ENJOY
@maxd5298
@maxd5298 Год назад
God's perfect design, this is evidence of a divine workmanship that is absolutely impossible by means of evolution. Psalm 139
@umanifestlife4394
@umanifestlife4394 Год назад
Thank you 🙏🏽
@phython124
@phython124 8 месяцев назад
Who created God
@maxd5298
@maxd5298 8 месяцев назад
@@phython124 No one, if we humble ourselves and empty ourselves of human pride, we can acknowledge that there is One greater than us, whose signature is all over creation, from the intricacy of the human body to the glory of nature to the vastness of the universe.
@phython124
@phython124 8 месяцев назад
@@maxd5298 I have no pride - don't worry about that. Yes he is above us but who or what created him?
@Norbertmoe
@Norbertmoe 7 месяцев назад
I have no clue, therefore I believe.
@user-dt6sr8pq4t
@user-dt6sr8pq4t 2 года назад
How great is our God creator
@tasneemalfani2063
@tasneemalfani2063 Год назад
قال - تعالى -: بسم الله الرحمن الرحيم ﴿ وَمِنْ آيَاتِهِ أَنْ خَلَقَكُمْ مِنْ تُرَابٍ ثُمَّ إِذَا أَنْتُمْ بَشَرٌ تَنْتَشِرُونَ ﴾ [الروم: 20]. سبحان الله !
@gainlabs
@gainlabs 3 года назад
*Jehovah : The Supreme Universal Geneticist* ♾️ 🔭🔬 glad the tiny humans are finally figuring it out, took them until 1984 to discover Kinesin. It was in operation long before that, so much more to discover!!! 😁
@Communist-Doge
@Communist-Doge 3 года назад
Evolution built these. :)
@TheBlueCream
@TheBlueCream 2 года назад
@@Communist-Doge nonsense
@MarSHornetsandWasps-v26
@MarSHornetsandWasps-v26 Год назад
@@Communist-Doge yeah, doesn't prevent Him from knowing kinesin was in operation, even assuming He hadn't built it himself
@S4M4R1T4N
@S4M4R1T4N 3 месяца назад
God is good.
@davenone7312
@davenone7312 2 года назад
And people actually believe that none of this is by design! That it just happened by chance and mutation. Not possible for this complexity at such a microscopic level, one single error and the entire cell is non existent and every cell after it. How does this cell mutate into a far more complicated one? Got to be a designer, a builder an architect one must conclude.
@KinnArchimedes
@KinnArchimedes Год назад
Maybe a f*kwit would conclude it. 🤣 How complex must the designer be to create such complexity, then who created the designer. It's just ends in a loop without a real answer. Edit1: you wouldn't even know about this to comment "God did it" unless vastly more intelligent people worked on the problem and found out what's really going on.
@user-dc9rf1sy1m
@user-dc9rf1sy1m 4 месяца назад
It ends in a loop because you falsely assume infinite dimensions. Surely, there is a 4th dimension, but theres no logical reason God has to have a designer in a dimension higher than him. Or else, he isn't God. He would be just like us. It's more correct to assume God has reached the wall of all the dimensions, and there is simply nothing beyond. You might say, "well how can that be, God must have a God higher that created Him". The fact is, you assume your logic is sound, which means your mind has been formed in the ONLY correct way that accurately describes reality, which means, it must have been created from a sound mind. If not, then you can't even claim your own beliefs as accurate. You cant simultaneously be an accidental consciousness that formed from random accidents, and also, have a brain that is programmed in the only precise way that accurately perceives your reality. Your brain is either created with the ability to discern reality, or it's an accident, which hallucinates "reality" which could entirely be false, in which case you shouldnt be making any claims of intelligence whatsoever.
@ibraheemtech6787
@ibraheemtech6787 4 года назад
And thay say there's no god سبحان الله
@crocopix
@crocopix 3 года назад
prove there is one , your ignorance of the origin does not prove anything.
@TIR4NO
@TIR4NO 3 года назад
There could be a god operating behind every single atom of every single kinesin, in every single cell of every single organism. But it would be stupid for us to even create a name for a designer capable of that. We should work more intensely over the minor details, and who knows... Perhaps one day we'll be able to put all the pieces together and build a god from them. The only thing that I'm sure about, is that science is the best tool we have in order to discover a god ruling the universe.
@Charles2k
@Charles2k 3 года назад
@@TIR4NO It's the same mystery of dark matter or to even comprehend that there was simply nothing before the big bang. It's just funny avant-garde athiests and thiests battle eachother to death over such topics cyclically.
@TheBlueCream
@TheBlueCream 2 года назад
@@azertyuiop432 u repeat ur comment ?...u sound like a religious fanatic
@mahmouddridi386
@mahmouddridi386 2 года назад
Quran "We will show them Our signs in the horizons and within themselves until it becomes clear to them that it is the truth. But is it not sufficient concerning your Lord that He is, over all things, a Witness?" Quran "Travel through the land and observe how He began creation. Then Allah will produce the final creation. Indeed Allah, over all things, is competent." Quran "Recite in the name of your Lord who created - Created man from a clinging substance. Recite, and your Lord is the most Generous - Who taught by the pen - Taught man that which he knew not.
@patrickfitzgerald4810
@patrickfitzgerald4810 5 месяцев назад
Bullshit
@boughefila
@boughefila 3 года назад
Allah Hou Akbar
@LV4EVR
@LV4EVR Год назад
"All of these questions that one wants to know the answer to..." Seriously? The evidence of God's miraculous creation are screaming at you, but you won't listen. You have rejected the very God that created YOU, and the mind-boggling complexity found in every living being, even at the nano particle level and beyond. If you truly want to understand, repent of your rejection of Him. Admit that you were "fearfully and wonderfully made" by God; you owe your very existence to Him; you've violated His laws and commandments. Accept that He came here willingly as a human in Jesus Christ, died to pay the punishment for your sin, and rose again, overcoming death itself. He, alone, offers you eternal life. If you deny Him, He will deny you and your "after life" will be spent in perpetual torment in a very real place called Hell. Yes, you are free to choose. That means you are also free to choose life, to choose to love, follow and submit to the very one that gave you life to begin with. Ask God to forgive you, and accept Christ as your savior-this is my prayer for you today. In love and peace.
@upscale4058
@upscale4058 Год назад
ALLAH O AKBAR (Glory be to ALLAH)
@hwd71
@hwd71 4 года назад
Evidence for Intelligent Design. The Lord Jesus Christ. ❤✝️🙏✝️⚓✝️
@boxdemension
@boxdemension 4 года назад
No
@hwd71
@hwd71 4 года назад
@@boxdemension A nano biological machine must've been intelligently designed. Can you at least agree on that?
@boxdemension
@boxdemension 4 года назад
@@hwd71 No. Just because we perceive similarities between biological systems and actual human-made machines is no proof that the biological systems were deliberate. It's very unscientific to assert X because it "makes sense to me"
@hwd71
@hwd71 4 года назад
@@boxdemension Can I convince you that the Pyramids only have the appearance of design? That they are actually three hills that just happened by the product of random chance action of wind and erosion over millions of years to look intelligently designed but are not? Is that a reasonable assumption? Did anyone actually see them being built? And after all they are made up of the same material as the surrounding rock.
@boxdemension
@boxdemension 4 года назад
@@hwd71 no. These aren't appropriate comparisons. Again, this is very unscientific. You can't go around looking analogies and similarities between things and say "this looks complicated. It must be designed." There are whole fields of study dedicated to finding out the origins of these complicated biomolecular systems. There are research articles proposing tentative evolutionary pathways for things like ATP synthase undergoing scrutiny and peer review. If the creationist "proof by analogy" method is so foolproof, where are your Nobel prizes? You'd essentially be proving the existence of a God. The number of "this is OBVIOUSLY designed" comments I see under a video showcasing a biomolecular systems seems to correlate with how analogous that system is with actual human made things.
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