1st-Ever FDA-Approved Longevity Drug? [2023]

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BREAKING NEWS: For the first time in history, the US Food & Drug Administration has given conditional approval for a drug that was developed, not to treat a specific, FDA-approved disease, but to “extend lifespans.”
This is huge! Does it mark a shift in how the FDA looks at life-extending drugs? Does it mean that time when the FDA recognizes “aging” as a disease, one that can be treated and possibly cured, is drawing closer?
Does anyone else think this is as big as I do?
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Chapters & Timestamps:
Intro: 00:00
The FDA: 00:41
The Big News: 02:40
What Loyal Did: 03:55
How Loyal Got FDA Trial Approval: 06:02
The Implications: 06:50
Wrapping Up: 08:27
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Social Media:
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11 июл 2024

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Комментарии : 95

@liuwang2201 7 месяцев назад

The FDA is for sale to the highest bidder

@ogungou9 7 месяцев назад

Of course. Capitalism my friend, capitalism...

@user-ok7nw3hd4k 7 месяцев назад

@@ogungou9 You would not have an FDA or any other three letter agency, all of them are designed to destroy freemarkets and give advantages to some as they are the highest paying lobbists. We have nothing close to real Capitalism, we have a goobermint up for sell, when under Capitalism the Government protects individual rights and the freemarket system that is self regulating without these predators interferring.

@mdavid1955 7 месяцев назад

About time!

@LanceHitchings 7 месяцев назад

Abosolutely!

@bernardedwards8461 7 месяцев назад

There is a rare genetic disease called progeria which causes children to age ultra-rapidly, so by the time they are ten they have the physique of a 90-year-old. Regardless of whether this drug works for ordinary people, it must surely be worth trying in progeria cases.

@Schu2505 7 месяцев назад

Acknowledgement is the key. I thought the same thing when I saw this news! We’ve moved into a new world!

@LanceHitchings 7 месяцев назад

Agreed!

@VTVT1306 7 месяцев назад

I’m already practicing to bark. 😊 Thanks Lance, that’s good news.

@LanceHitchings 7 месяцев назад

I agree. You're most welcome.

@lpg12338 7 месяцев назад

🤣 👍

@Pluvo2for1 7 месяцев назад

Hi Lance I remember you saying in a comment a while ago that you were using trouble shaking off belly fat. If you've had some succes with that problem could I ask what you did?

@magickmagazine7675 7 месяцев назад

I cared for the dog Cilla, who is the oldest on record in The Guiness Book of records - 36 human years - she was a medium to large dog -

@LanceHitchings 7 месяцев назад

Interesting. I thought the oldest dog was Bobi, who was 31. There was another dog named Chilla, who was 32, from Australia.

@WilliamThirteen 7 месяцев назад

Woof Woof!

@SamuelMartin-gi9ed 6 месяцев назад

Love to see it thanks man! Please cover AQST stock if you get time. They have price targets of $12,16 and 24 now which is a little crazy. Maybe it can hit $6 again. It was at $6.40 then they got rejected for libervant in 2021 and now it looks like it will be approved in a few months which could be a billion dollar product!!!

@emad5009 7 месяцев назад

As long as we can live longer and stay sick, big pharma won’t mind

@LanceHitchings 7 месяцев назад

Yeah, but the drug was developed to "extend HEALTHY lifespans."

@flukymorrow6830 5 месяцев назад

I didnt "think" this when I read about it, I "knew" it. Its a no brainer. Dog lives 12 years and now you can add another year. Not a big deal but if they can go as far as adding 4 years. Well then people will buy it for their dog. If it works on the dog then what could it do for us? Add an additional 40% to our life span? Take that times 73 and you have an additional 28 years. Now the average life span is 100 years. People can and will work till they are 75 or 80 and wait to collect social security. That means a work force that works way longer, saves more in retirement, pays their debts off and doesnt need to collect social security until they are 75. What is there not to see here? This benefits the rich big time. Larger work force, less drain on the budget and more money being dumped into the stock market! Of course major companies like Walmart would love this.

@joshlocher71 7 месяцев назад

if you could will you do a presentation about david sinclair i recently found out that they found age reversal chemicals and also that can be put into a pill

@LanceHitchings 7 месяцев назад

So, here's the thing, Josh. I'm not a big fan of David Sinclair. I spent a few days with him while in Costa Rica for stem cell therapy (he was down there getting stem cell therapy at the same time.) I found him to be arrogant, self-centered, demanding, controlling, and very high-maintenance. His track record with first resveratrol and then with NMN has left a bad taste in my mouth. So, no. I won't be doing a video about David Sinclair. Sorry.

@HCW2855HCW 5 месяцев назад

Sinclair is a fraud.

@mag4926 7 месяцев назад

As if the FDA were interested in the well-being of the population...😂 I just have to 😂! In my opinion, the FDA is comparable to *gangrene...*

@roberthamilton606 7 месяцев назад

FDA is afraid to approve all but the best most funded drugs because nothing happens to them if they deny approval of a drug, but if they approve drugs they are putting their jobs on the line if they approve a drug and it later is determined to be detrimental, since we have to have fall guys and it ends up being the FDA personnel instead of the drug company ( often). So it is a broken system. No approval is safer than approving many worthwhile but questionable drugs.

@AH4Z 7 месяцев назад

Put dogs on a fresh food diet with necessary supplements for vitamins and minerals add some taurine and the extension is unreal. Dried kibble, let’s not go there except for convenience when necessary.

@LanceHitchings 7 месяцев назад

Like I said in the video, dogs are impacted by the same environmental variable that we are...like a good diet.

@johnfontana7256 7 месяцев назад

Thanks , I’ve decided to die exactly when I’m supposed to , not a second later! My ego will be clawing concrete to get me another second!

@LanceHitchings 7 месяцев назад

To each his own.

@SteveRichfield 5 месяцев назад

Maybe - and maybe not. Most dog breeds are hundreds of years old, rather than hundreds of thousands of years old like humans. Many are based on random mutations that have life-shortening effects, like pugs that have breathing problems. It seems possible that drugs could be developed to address certain specific issues in large dogs that have absolutely nothing to do with human physiology. So, the BIG question is: How do these drugs work?

@franklanham6936 7 месяцев назад

I think Lance has a valid point - this could be a turning point for the FDA. A possible problem might be that Health Insurance companies will probably not want to ensure for a condition that everyone gets if they are lucky - old age.

@LanceHitchings 7 месяцев назад

But here's the thing. The amount of money that insurance companies spend on treating age-related chronic disease far outstrips what they might spend on simply maintain good health. They would save so much money!

@franklanham6936 7 месяцев назад

@@LanceHitchings that would be true if we approximated the ideal of living in good health until three weeks before our death. Let’s hope!

@synaestesia-bg3ew 7 месяцев назад

@@LanceHitchingsi remember your first video from the start and I noticed some changes, you really sounds and looks younger. You are definitely on your way.

@moniryousefian8782 7 месяцев назад

@@LanceHitchings Can you guess what is the name of the drug ?!

@LanceHitchings 7 месяцев назад

@@moniryousefian8782 Loyal's calling it LOY-001. They didn't say what it is, but they did mention what it's not. It's not rapamycin, a rapalog or metformin. I don't think it's anything we've seen before. In their trial application, they said that it was developed to "extend lifespans" in dogs. There's no current drug that I know of that was explicitly developed to extend lifespans.

@joshlocher71 7 месяцев назад

i can't believe it this was the best news yet your familiar with david sinclair right i hope he sees it i like him a lot

@safffff1000 7 месяцев назад

Have you looked into anipryl

@LanceHitchings 7 месяцев назад

Not really.

@safffff1000 7 месяцев назад

@@LanceHitchings It's for dogs and is also called Deprinyl. 40 yrs ago, studies showed up to 40% life extension in rats. I took 30yrs ago, and it cured my bad back. In the rat studies, it showed realignment of the skeletal structure. Unfortunately I got the citrate which the powers to be jailed its creator and forced it off the market. It's still available in the other form, which was used in the dog studies.

@cliffcastle9808 7 месяцев назад

Could you please provide your definition of "aging" and how it in fact differs from "growing old" biologically.

@LanceHitchings 7 месяцев назад

First, I'd need a definition of "growing old" biologically. First time I"ve heard that term.

@cliffcastle9808 7 месяцев назад

There is biological age and chronological age . There is aging for each right? Growing old (in my opinion) would be showing the signs of aging. Longevity could apply to either or both right?

@lizardfirefighter110 7 месяцев назад

Now you will see people with large dogs renting them to old people. Then these people will gobble up the dogs longevity prescription. It will be a win win arrangement. Funny thing is if the local vet recognizes a dog having several elderly owners living at different addresses…😂😂😂

@user-es1hk6ok5w 7 месяцев назад

FDA Approved Longevity Drug it will probably do minus effect😂

@wildflower-web 7 месяцев назад

FDA behind the curve again, a dog is not a human.

@stevenr5149 7 месяцев назад

big thumb down for another "THIS CHANGES EVERYTHING" title. I shouldn't have to say that either. Hmmm. Nothing seems changed now. "everything" you said. 👎

@LanceHitchings 7 месяцев назад

I absolutely stand by what I said. Longevity research hasn't, until now, been considered "de-risked." Longevity companies don't have a proven track record at developing AND commercializing drugs. So, while there are investors, the big money is staying away. But if the FDA recognized that "extending lifespans" is a legitimate goal for drug development and that success is "likely," then this might be the signal that investors need to start moving big money into longevity research. And in biotech, success is correlated with capital investment. With FDA approval, we should start seeing funding and grants being steered towards longevity. And if we do...THAT CHANGES EVERYTHING.

@galladiel 7 месяцев назад

It's naive to think that what holds FDA back is the assumption that longevity drugs are unlikely to succeed. If there were drugs that could help extend lifespans, they would do anything in their power to stop their development. This agency is deeply corrupt.

@rodneybaker5562 7 месяцев назад

I follow anti-aging and use various drugs to counter same. Can absolutely tell you an injectable is coming that will reduce your age by 1/2. In fact I’m learning how to do the chemistry’s (which anyone who has the will to learn can do) so I don’t have to wait on the FDA to approve my personal use. Watch the news in 2024. You’ll start hearing about it.

@tridoc99 7 месяцев назад

Aging, like pregnancy, is not a disease. They are normal parts of life. But that doesn’t mean we shouldn’t try and improve on those conditions with science. The problem isn’t not considering these disease, the problem is the FDA’s stupid requirement that something be considered a disease in order to approve trying to fix it or make it better.

@viracocha2021 7 месяцев назад

Cancer/CVD/infections are not a diseases but part of life. They are the normal operation of cells...

@LanceHitchings 7 месяцев назад

Agreed. The whole "aging is a disease" is a political stance required to get the FDA to acknowledge that aging can be treated.

@tridoc99 7 месяцев назад

@@viracocha2021 No. What does the D in CVD stand for? Cancer cells are not normal cells as there has been a mutation in their DNA, and infections are also by definition a disease. That is why the CDC operates the Center for Infectious DISEASE. Are you seriously trying to equate these things with the natural process by which humans (and many other animals) propagate the species and the process which all living things undergo?

@SamShank175 7 месяцев назад

I think it's interesting and that there could be benefits to aging being considered a disease. I have a couple of issues though. 1. I heard about the drugs to extend the lives of dogs earlier this week, my first thought was that this company found a new way to prey on people's love for their dogs. I couldn't help but think that they started on this mission not because of their own love of dogs, but because they were looking for a money maker. 2. The other is your use of the word 'cure', has a drug ever cured anything? They usually just treat symptoms. The exception might be antibiotics, but they've also left a lot of destruction in their wake.

@LanceHitchings 7 месяцев назад

Wow, cynic? I've read & watched several interviews with Celine Halioua, the Founder and CEO of Loyal, and I would hazard a guess that making money is a very low priority for her. They're working to keep the cost of the drug in the low to mid double digits. And yes, drugs have cured lots of things. I used to have Hep C and now I'm cured, thanks to drugs developed by Big Pharma.

@benoitseguin625 7 месяцев назад

l hope David Sinclair has seen this so he can even go faster. l'm sure he has. This is great news for this area. And with the great help of AI l'm sure 2024 will be groundbreaking in this area. Thanks for posting this very interesting. Lynn Seguin

@soylentmajority989 7 месяцев назад

Sinclair is the biggest obstacle to life extension. His history is to deny people access to Resveritrol and NMN.

@johnf4680 7 месяцев назад

David Sinclair is not interested in Science. He cannot be trusted. Find one of his studies that has been reproduced. Good luck.

@LanceHitchings 7 месяцев назад

Yeah, I agree the AI will have a huge impact on longevity. Having met Sinclair, I'm not sure I agree that he's the hero of longevity. I thought he was arrogant, self-important and high-maintenance. He seems more interested in making money than in advancing science.

@danhayes5225 7 месяцев назад

don't think that is going to have any effect for experimental human old age drugs approval

@LanceHitchings 7 месяцев назад

You may be right, but we can hope. I think that what made this trial viable is the fact the giant & large breed dogs only live about 10 years, at the most. Humans can live to 110 or more. Even if they start a trial when they're older (like with the dogs) it'll still take 50 years or so to complete the trial.

@Pluvo2for1 7 месяцев назад

I wonder how many of us desperate humans would take a risk with this dog medicine.

@Letsplay222 7 месяцев назад

It's kinda ridiculous that the FDA needs to approve drugs for dogs.

@trojanthedog 7 месяцев назад

So we get 30 yr old dogs before we get 150 yr old people!🤨

@LanceHitchings 7 месяцев назад

I don't think that'll be the case. Loyal's drug only adds a few years to the lifespans of large and giant breed dogs. So a Great Dane might live to 10 or 12 instead of only 6-8.

@manuelojeda9144 7 месяцев назад

Well they're for money

@thierryvidal63 7 месяцев назад

The FDA doesn't regulate veterinary products, including drugs,

@LanceHitchings 7 месяцев назад

Yeah, they do. They're regulated through the FDA's Center for Veterinary Medicine (CVM) and governed by the Federal Food, Drug & Cosmetic Act (FFDCA).

@hartlandsnyder7689 7 месяцев назад

It seems likely that the primary beneficiary of this recent decision will be to further expand the scope and the power of the FDA. What appears to have happened over the last 4 billion years is the rate of evolution has overall accelerated quite a bit. For this evolutionary process to continue ramping up not only requires that you and I will die, but that virtually every extent speicies must also perish. For my part I simply intend to make an increasing contribution for as long as I am able; an important part of which is to enable our children to continue to empower themselves. Perhaps the most propitious way move ahead is to obsoletes the FDA by allowing new processes and organizations to come to the fore, flourish, and then also go extinct.

@LanceHitchings 7 месяцев назад

I couldn't agree more that the FDA needs a complete overhaul. Whether or not overall evolution is speeding up or has been happening faster that we though all along is debatable. Humans, though, are apparently evolving faster.