NAC & Glutathione: Health Benefits + Testing Explained 

Isn't it interesting that the FDA warned about NAC during C19, and then Amazon stopped selling it. BUT, when the plandemic was over, Amazon began offering it again.

When using garlic in a recipe; chop fine, add fresh lemon juice leave for 10 minutes and add in the last minute of cooking to your food. This enhances the allicin and sulphur compounds...which in turn will help your system to make NAC and Glutathione. Protein rich foods plus any sulphur rich foods plus Vit C will enhance NAC and Glutathione naturally. Thanks Mike. Happy everything folks. 🥳

Great content! Regardless of the reasons given I think NAC being temporarily pulled during the “pandemic” as more people were purchasing it was no accident. They knew it had multiple benefits.

NAC breaks down mucus. Really helpful

Thank you Mike. I’ve been taking NAC since I was given last rites in ICU from Covid 2020. Somehow I pulled through with many many terrible issues. I started taking glycine for diabetes and found out it worked well with NAC for lungs and many other health issues.

I have suffered with a condition called Trichatillomania (eyelash pulling) since the age of 10. I am now 55. I have been treated with everything under the sun for this condition. NAC has cured this issue. I take 1300 mg twice a day.

We have been using cysteine since the 1990s when my 7 yo son, who was poisoned with pesticide, had an amino acid test. Both blood and urine were low in cysteine, taurine, and phosphoethanolamine. L-cysteine supplements raised his cysteine and taurine levels to normal and decreased his ongoing symptoms by about 70%. NAC also in Merck Manual for Tylenol poisoning and in NEJM 2006 article for gadolinium induced kidney damage from the contrast for angiograms. Thanks for spreading the information about this most important supplement.

Something to consider is that the powdered form of NAC has a shelf life of around 2 months while the capsules have a shelf life of 2 years. I researched this because some NAC bottles I have are nearing the expiration date. Unless you're going to consume all your NAC powder in 2 months the capsules may be a better option.

I've been taking NAC for well over a decade. Originally for osteoarthritis requiring bilateral hip replacements at a fairly young age. It's beneficial effects have been masked by the other upgrades I've made like like low carb, autoimmune diet. But what I'm reminded of every day is what a great bronchodilator/expectorant low dose NAC taken 3-4 times a day can be. A higher dose taken once a day can cause a little bronchial congestion, but a 300-400 mg dose with meals and at bedtime is better than any inhaler I've tried! All of NAC's beneficial effects are appreciated, but nothing reminds me of it more than being able to breathe easily. I rarely come across any info on NAC that I didn't already know, but I watch every video Mike makes about NAC because I need constant reminders to keep me from taking it for granted. (I watch every video Mike makes no matter the subject, and I learn an immense amount). Thanks, Mike.

I take NAC and magnesium glycinate at bedtime. Helps my muscles unravel and great sleep

Would love to see you talk about Nitric Oxide production Mike. I watched an amazing interview between Jesse Chappus and Dr. Nathan Bryan and it blew my mind how connected Nitrates/Nitrites/Nitric Oxide are to virtually all chronic diseases.

I take 600 mg in the morning on an empty stomach. It has cured my gut issues pretty much. Unreal! So happy I ran across this.

I had been taking NAC, glutathione, and glycine every day for months and my levels were ZERO. Turns out, mold toxicity and zero enzymes are being made by my pancreas. I was prescribed antidepressants for 20 years without knowing I had mold toxicity the whole time... I have MTHFR and HLA gene mutations making it impossible for me to methylate and excrete certain biotoxins.

Thank you SO much Mike!! No doubt from everyone who loves you. We can’t say it enough for all your hard work. Merry Christmas Everybody!!

Thanx for all your hard work, Mike! Now if I could get my loved ones to take this. Happy Holidays! ☃️🌲✨

Thank you for putting out helpful information to keep your tribe healthy🙏🎄

Mike, I just want to wish you a very Merry Christmas! I am grateful for you and I am incredibly thankful for your solid work in support of my health and wellbeing. I was able to share this knowledge with my loved ones as well.❤

Started taking NAC yesterday. Had the best sleep of my life that following night.

Thanks, Mike. I'm 70 yrs old and (after 3 vaccinations) I caught the plague in the summer of '22, mild symptoms but had serious respiratory and energy issues well into 2023. Started taking nac and glycine this summer before getting hit with the same virus at Thanksgiving. Again, relatively mild symptoms, BUT I bounced back completely within two weeks with no residual after effects. Makes me wonder if those with long covid wouldn't benefit from NAC. Merry Christmas to you and your family!

I started using NAC when I was diagnosed with NAFLD during C19 lockdown and was offered no treatment options. I read a few papers and decided to try it. I hadn’t considered buying NAC in powdered form. NAC was never unavailable here in Canada despite the supply chain issues during C19. The capsules are still pretty cheap, especially once you weigh in the benefits. I use magnesium bisglycinate capsules too. I think I have a good combo going on now. I’m 70+ years old and living young and well with self-managed autoimmune conditions. My rheumatologist tells me I should never stop the NAC and lauds it as a great supplement for seniors. He also encourages the use of cannabis as a wellness adjunct among seniors. This young guy calls it going old school. He’s now also teaching at our closest med school.

I’ve been taking 3 nac tablets a day since 2020. 1 morning 1 afternoon , 1 night, each at 1g. and I haven’t had any major sicknesses. Even the cold and flu, even while being around people who have the flu, I feel like it’s boosted my immune system.

Thanks for posting the recommended dose and time of day ! I bought 2.5 lbs of NAC in2020 when I found out the FDA told retailers to stop selling it. I just need to get back in a regimen with it.

Hi Mike been subbed to your channel for years. Can't remember when you first mentioned glutathione, but it sparked my interest and remember someone said it improved blood flow. Well I used to get very cold fingers in winter - sometimes they would go white. I bought some glutathione tablets and was shocked. Completely cured this. So much so that my hands and fingers are always warm. So thanks.

Thanks for the info man, God bless you.

Love this! What do you think about ground/earthing bed sheets & standing mats that are being advertised everywhere? Can you do a video?

Not telling anybody else to do this, but I take about 3 grams of NAC daily and supplement with 2 grams of glycine for liver health (and milk thistle) , AST and ALT levels both extremely good at 26, even though taking acetaminophen daily for back injury (ex- competitive bodybuilder) for about 6 years now. I am an endovascular guy, NAC is amazing, actually when patients present to the ER for acetaminophen poisoning, NAC I.V. is first line defense and started to detox liver. Also, I'm a Factor-V, great video BTW

I originally started taking NAC at the advice of my therapist to control my trichotillomania. It worked after one week. The added benefit of taking NAC was that it helped with my asthma symptoms and stopped my yearly bronchitis

Thanks Mike, another excellent and informative vid - my MSc research is on chronomedicine and fasting and also yielded some insights for myself into oxidative stress and inflammatory processes in re circadian rhythms. fascinating topics! In the UK we can get a month's worth of liposomal GSH for around $50 with B6 and Se in the formulation too. Sometimes difficult to get hold of NAC powdered here tho

Thank you for this interesting information. I love your clever wording to get around the YT overlords. Good job!👍🏻 I started taking NAC and Glycine about a month or two ago. It does seem to help my sleep. I usually take it late at night.

Thank you Mike. Very informative.

Never got sick or 'the product' and was taking this for 2 years. Oh and I broke the rules. It helped with the constant inflammation of my bladder and tendency to infection, too. Apparently it attacks biofilms. After about 3 months, I also noticed things like mood swings and lifelong rumination mellowed considerably. I took 700mg powder/day.

Great presentation Mike.

Great info on sleep!! I’ll try switching from morning NAC/ glycine to before bed .

Good stuff. Thanks for the information, I appreciate it.

Thanks, Mike. I’m currently taking NAC along with magnesium glycinate hoping it helps with overall health and diminishes panic attacks and health anxiety. Wishing you and everyone here a Merry, Merry Christmas. Feliz Navidad desde México

Interesting regarding timing. If take them before bedtime my sleep is restless. Take in the Morning, I sleep great and my asthma is lessened.

THANK YOU ❤

Thank you Mike your truly bad ass !

I know we're not talking about it but NAC cleared my lungs that got crazy congested from covid. It definitely treated my lung congestion, no doubt!! I was able to get off my couch without fainting thanks to NAC.

I've had a pretty bad case over the last few days. Made a cocktail of Kalmegh (indian echinacea), L-Glutathinone, Aspirin and potassium citrate+calcium ascorbate+magnesium bisglycinate and it made a night and day difference. Can't say it helped me get better faster, but it makes me feel normal instead of miserable. Though it definitely warded of periods of deathly-feeling weakness.

Very helpful video, thank you :D

Yes, timing and dosing do matter. Thank you.

I take NAC for neuropathy symptoms. It certainly doesn't cure it or take away the pain. It does reduce to pain to an almost manageable level though. I stopped taking it for a while and the pain got much, much worse. I started taking it again and the pain is reduced. I started giving it to my 2 autistic kids when they were sick. Not sure if it helped them feel better sooner or not but it has improved their moods significantly so they still take daily.

I don’t take NAC regularly but do take it. I have to be careful and not take it close to times that I have bloodwork or anything where I might bleed because it is a blood thinner. It is minimal but I try not to take it a few days prior. I must admit, I have been able to avoid illness with the use of it as well as electrolytes and a low carb diet. 🎉

Top class information 👏

I was using Glutaryl, a transdermal (not liposomal) Glutathione, and my doctor suggested I stick with NAC fearing that taking straight glutathione would down regulate my body's ability to make it. The Glutaryl has some good data but is expensive

I’ve been taking 600 mg NAC PROB FOR AT least 10 years . Started taking for my Hashimoto And I Never looked back .Hands down my Favorite Supplement next to Creatine .❤❤❤ Energy Health strength skin Love it !!!

Much like calcifediol can ramp up D3 in 4-5 hours instead of days (as was used for Covid in Spain) Liposomal GSH is in the marketplace for those who are in dire straits, or who don't process NAC into GSH for whatever reason(s).

I took NAC when I had covid and it really cleared out my congestion. I was able to find it at the vitamin shoppe and I've kept taking it because of its health benefits. I also have had a pulmonary embolism many years ago. I was prescribed a daily aspirin a day but I think the NAC is a better choice! Thank you for this information!

This is reassuring. I’ve been taking glynac every night before bed. Thanks Mike

excellent content

Thanks for useful information. I gonna try taking NAC + glycise

Very good 👍 thank you ❤

Great video, here is a summary NAC and Glutathione Overview: The video discusses the health benefits of N-acetylcysteine (NAC) and its role as a precursor to glutathione. Glutathione is emphasized as crucial for overall health, particularly in the context of infections, including its antioxidant properties and potential benefits during viral infections like COVID-19. Mechanisms of Action: NAC is highlighted for its ability to increase glutathione levels by providing cysteine, the rate-limiting amino acid for glutathione synthesis. The discussion includes the role of glutathione in neutralizing oxidative stress and its potential impact on the clotting cascade during infections. Benefits During Infections: The video presents evidence suggesting that NAC treatment can reduce mortality in severe COVID-19 cases, improve blood oxygen ratios, and decrease markers of inflammation and clotting. Dosage and Timing Recommendations: Recommended NAC dosage ranges between 800 and 1600 milligrams, preferably taken at night. Timing considerations include post-infection periods, after prolonged sitting or travel, and evenings, aligning with the concept of chrononutrition. Comparison with Glutathione Supplements: The video compares the cost-effectiveness of NAC as a precursor to glutathione against direct glutathione supplements, suggesting potential savings with NAC while achieving similar results.

This helps with depression, anxiety, and also preventing COVID.

Liposomal Glutathione seems far superior in my experience. Never have been sick since starting it.

Thank you so much, my take from this video is to take glynac in the evening, thanks a bunch!

I have been taking NAC and I never want to stop. It is good. I appreciate this video because sometimes I forget and skip a day or a few days, and I don't want to let it slip. So this is a good reminder. I like the tip about buying the powder form. Good idea.

Its also the precursor for ceruloplasmin, which is the primary mobilizer of copper. Half of more of the general population is copper toxic ( JOM ) and so NAC + mild zinc supplementation will slowly drop copper toxicity in tissues. There is no blood test that can detect this. You have to get a hair mineral analysis. Most doctors don't knew anything about this, FYI.

Taking a scoop every night on month three now! Thank you.

Thank you

For me, I noticed that if I take it before bed, it keeps me up. It’s like electricity running through my system. So I take it with breakfast and at lunch.

I just came across your channel. Your videos are the most in-depth, so thank you! Quick question; you mention that antioxidants taken during the day is bad for the body (vs at night). Does this also apply to antioxidants from food? I drink a 64oz smoothie (water + frozen berries) during the day😬. Let me know! Thank you!

It's a shame he still has to tip toe around NAC. Edited because of RU-vid's censorship.

Remember the L-Glycene (glynac) and the Serine!!! Also, 5 htp for serotonin production (5 hydroxytriptophan).

I read that NAC is most effective on an empty stomach so right after waking up is when I take it. And glycine before bed. Any proven studies on timing?

Have you looked into GlyNAC before? Very interesting research on it.

Thank you!! I didn't know we should take NAC at night instead. I've taken it sporadically and randomly, to try and stymie colds, and had mixed results. I will become a smart hummingbird and try taking it just before going into torpor and see if it makes the difference.

Hi Mike, hope You're doing great. Do you take glutamine to go with nac and glycine? Thank you sir

Been using injectable (subq)glutathione 100mg, 50mg nac, glycine 5x week. Made a huge difference in how my skin looks. Dont need gram amounts of dosing subq.

Seems like you could augment the Zelenko Protocol with NAC and GSH

NAC is a dose dependant Mtor inhibitor. That’s why glynac dose is so high imo .

I find the time to take it interesting b/c it seems to work better for me if I take it in the evening.

Well. Common antioxidants talked about ate vitamin A and vitamin E which are recommended to take in the morning. Are they good to take in the morning? I actually think clove, lemon balm and many other herbs and spices are better antioxidants than vitamins. I might try my clove at night now.

You could have talked a little more on Glycine such as dose to be taking with the dose of NAC

I take NAC and glycine pre work out for Engery

I read L-Alanyl-glutamine injectable is a stable version, but is a dipeptide composed of alanine and glutamine, and is what is sold mostly in Asia. Will this have the same effect as taking "pure" L-Glutamine injection?

one lady said her dad was being treated in the hospital for bacterial pneumonia and he tested positive for fungal infection. she said he was never treated for fungus. I read that Nac can help keep a person with covid out of the hospital.

Hmm what does it mean if GGT is low ( 4 IU/L)? I would think treatment would be different than if levels were elevated? My naturopath put me on NAC and explained my body is using up glutathione; does that sound correct? I was also fighting a virus at the time. What are prime levels because on my lab test is says normal range is 8-61. Thanks for all the knowledge you share! 🙏🏽

My mother had blood clots and heart damage from the Covid V.

00:20 "Nutritional support" Riiight 😉

Above 2g daily dosing it is effective as an antidepressant. I didn’t know this until I tried to suddenly stop taking it.

Hey Mike is there a benefit to taking the form ethyl ester?

Mike , the dosage you recommend seems a little bit off compared to what was shown to work in recent studies which said to take glynac @ 100 mg / kg of weight. Which runs into 6.5 g of Nac + 6.5 g of glycine for a 65kg person. That's way higher than the 800 mg to 1600 mg you recommend. Care to clarify plz ? Thanks.

What is difference between NAC and TUDCA?

I thought there was an issue with NAC causing a problem if you take it after drinking? That it is protective if fully metabolized before drinking? I have no doubt that you are correct - but a clarification would be helpful, thanks!

Thx

Thanks for this. I take half my dosage in the morning and the other half before bed. Is that ok?

Is it true that liposome forces absorption and if the cell is already topped off it can actually result in reactive stress on a cellular level (in this scenario I am referring to a situation where you are taking an infusion 1-2 times a month regardless of health conditions)

What about injectable glutathione? Can it me taken subq and is there a lot of pip?

I’m very sensitive to NAC because of mold / mycotoxins toxicity. I’m able to take glutathione IV and transdermal. I am nit quite sure why NAC makes me anxious and frazzled.

I notice my stomach works better! And less acid and better digestion

Mike, could you do a video on fibrinogen? It's important to not have too high a level to avoid clots.

Is taking Vitamin C with NAC(Glutathione) helpful or hurtful? GSH being mother of antioxidants, taking Vit C can be bad? Another question is NAC is OK to take with DHEA with no adverse effects? For people over 50. TIA.

Nac doesn’t affect things like wbc. It did help me with the coughing when I had Covid 19

good video. But u didn’t mention the common between NAC, Glutathion and Histaminintolerance what would be very important.

I take magnesium glycinate....this contains glycine ...is there an optimum dose of glycine you could recommend to take with the NAC?

Where did you get the dosing? All the studies show you have take for an average weight man about 8 to 9 grams.

Can’t I take magnesium-L-glycinate with NAC? Since L-glycinate is just the anionic ion or salt of L-glycine, correct?

did I hear right, NAC (AFTER) alcohol?? I thought that was a no no