What are SGLT2 inhibitors and how do they affect kidney disease? 

Thanks for the advice regarding SGL2 Inhibitors. For a future broadcast can you discuss the drug called Spironolactone and when it should be prescribed and if it has any benefits for kidney patients? Much appreciated.

I have been prescribed Farxiga by my nephrologist and even got a free botle with a cupon but Im not using it. Im not a diabetic or have proteinuria. Creatinin is about 1.5 the highest. Gfr not super high ( just don’t remember) is in the lower end. And Im heart transplant patient and I exercice 45 years old. I urinate a lot and always show signs of dehydration in my lab work. My concern is if I already show signs of dehydration doesn’t taking the med would make it worst. Ps. No prostate problem. Sometimes I can’t even have a good night sleep because of urinating so much. Thanks for the explanation. You have answered more questions in your channel without me having to look’em up that is amazing. ❤

Excellent presentation. I am on Sglt2 inhibitor and recently was increased to 25mg as my HgbA1C went into diabetic range, I have been on the medication 3 months. Should I be concerned that my GFR went lower from 51 to 49 on medication and when would the medication increase or stabilize the GFR?

Great information as always . Please keep doing it

I don’t have a nephrologist. My endocrinologist prescribed Jardiance for my DM 2 and Stage 3 CKD, 55 GFR and microalbumin/creatinine,urine 858 up from 279. Hoping going on plant based kidney health diet & Jardiance since September 2022 will help lower albumin in urine.

Any research with zero carb combined with SGLT2 INHIBITOR or fasting and SGLT2 INHIBITOR?

Hi Dr Thank you again for another highly informative video. Is SGL2 inhibitors effective on none diabetics GN patient? Thank you again

I would be grateful if you could also create a video on the topic of Finerenone and its impact on kidney health for DKD (non-steroidal Mineralocorticoid Receptor Antagonist (MRA)).

Hi, this was helpful. Can you guys also discuss GLP1 meds as well and compare to SGLT2 for CKD? thank you!

I heard apple peel powder is a natural sglt2 inhinitor...I wonder 🤔

Do you all know any studies linking kidney disease and properties of adaptogen mushrooms?

Hoping this will help my dad who has CHF and constant fluid buildup in the legs and lungs. Hopefully if sodium is excreted then logically less interstitial fluid build up.

I’m curious to know would you prescribe this for Someone with microscopic hematuria and proteinuria? Over an ACE/ARB? and If they are already being controlled with an ARB?

Thanks Dr. I have been on jiyadiance for around 4 years.

Hi, did you say all cause mortality dropped by 40% or 14%? Thanks

dr Hashmi is it ok to take with a arb that has a diuretic? My bp meds has a diuretic so will that cause a problem?

Maybe using activated charcoal capsules before eating anything will be able to help by absorbing the toxins from the bad foods and helping reduce kidney use thus helping kidney recovery?

Stage 3 ckd and high-ish bp. Do you prefer losartan or verapamil ?? Please advise. Thanks.

I take sglt 2 and linsinopril . Is this ok?

Thank You!

After 6 weeks treatment with Farxiga my blood test showed a rise in creatinine level and urine test revealed that sodium, potassium and cholride had all gone below the normal level. Farxiga did not have any positive effect on my proteinuria either.

Can SGLT2 INH Help reach autophagy faster?

The assertion made in the preceding statement regarding a 14% reduction in all-cause mortality requires clarification, as it inaccurately conflates the concept with relative risk reduction (RRR). It is important to note that the reported figure of 14% pertains specifically to the RRR, rather than the reduction in all-cause mortality. In truth, the reduction in all-cause mortality associated with the intervention in question amounts to a modest 1.6%. Drawing upon evidence from the JARDIANCE trials, it is indeed accurate to state that JARDIANCE demonstrated a relative risk reduction of 14% (hazard ratio [HR] = 0.86, 95% confidence interval [CI]: 0.74-0.99, P = 0.04). However, it is essential to distinguish between RRR and absolute risk reduction (ARR) when considering the implications of these findings. In the context of the composite endpoint, the ARR observed was merely 1.6%. By emphasizing the distinction between RRR and ARR, it becomes evident that the reduction in all-cause mortality attributable to the intervention is considerably more modest than the initially stated 14%. The nuanced interpretation of the JARDIANCE trials underscores the need for accuracy and precision when discussing the effects of medical interventions, particularly with regard to outcomes as critical as all-cause mortality.

Is Metformin safe for patient ckd

What about GLP-1-R

Zero carb improve my HBA1C from 10.2 to 5.2 in 3 months with fasting

Finerenone ?